Orthopedics. Tissue modeling. Even the future of robotic microsurgery. Purdue’s focus on Bioengineering brings many disciplines together at world-class facilities. Biomechanics can be tested on a human scale, while cutting-edge disease detection and treatment can be explored on the nanoscopic level. Whether it’s the impact of a car seat on someone’s posture, or the impact of pharmacology on microorganisms, Purdue researchers are at the forefront of biomedical engineering.
Faculty in Biomedical
- Modeling and simulation techniques for multiphase and multiphysics problems using the phase-field method.
- Isogeometric methods with applications in fluid and solid mechanics.
- Modeling and simulation tools for several biomechanics problems, including tumor growth, cellular migration and blood flow at small scales.
- Computational methods for fluid-structure interaction, especially when the problem involves complex fluids.
- Predictive, multi-scale modeling and simulation of microstructure evolution in confined granular systems, with an emphasis in manufacturing processes and the relationship between product fabrication and performance.
- Application areas of interest include:
- (i) particulate products and processes (e.g., flow, mixing, segregation, consolidation, and compaction of powders),
- (ii) continuous manufacturing (e.g., Quality by Design, model predictive control, and reduced order models), and
- (iii) performance of pharmaceutical solid products (e.g., tensile strength, stiffness, swelling and disintegration), biomaterials (e.g., transport and feeding of corn stover) and energetic materials (e.g., deformation and heat generation under quasi-static, near-resonant and impact conditions, and formation and growth of hot spots) materials.
- Thermal stresses, thermal fracture and fatigue of advanced materials, in particular high temperature materials, ceramic coatings.
- Mechanical behavior, design and remodeling of biological tissues, effect of stresses on remodeling, microbiomechanics of cell-extracellular matrix (ECM) interactions, tissue engineering
- Discrete element method (DEM) modeling for particulate systems
- -- model development, e.g., fibrous particles, particle breakage, particle shapes
- -- application to manufacturing, e.g., storage and flow, blending, segregation, drying, coating, wet granulation
- Finite element method (FEM) modeling of powder compaction
- -- e.g., roll compaction, tableting, picking and sticking
- Multi-scale modeling (FEM combined with DEM) of powder dynamics
- -- model development and application to hopper flow, blending, and segregation