Li Zhan

Li Zhan

Assistant Professor of Mechanical Engineering and Biomedical Engineering

Location: West Lafayette

School of Mechanical Engineering
Purdue University
585 Purdue Mall
West Lafayette, IN 47907-2088
lizhan@purdue.edu

Degrees

  • Postdoctoral Fellow, Massachusetts General Hospital and Harvard Medical School, 2024
  • Ph.D., University of Minnesota, 2020
  • B.Eng., Xi’an Jiaotong University, 2014

Research Interests

  • Biomanufacturing and biopreservation
  • Microfluidics
  • Biotransport
  • Micro/nano biomedical devices
  • Diagnostics

Fundamental Research Area(s)

Application Area(s)

Selected Publications

Guo, Z., Zhan, L., Finger, E., Hays, T., and Toner, M., Bischof, J. Enhanced heat transfer for improved ice-free cryopreservation - Interplay between cooling and rewarming. Annual Review of Heat Transfer, 2024; DOI


Zhan, L., Edd, J., Mishra, A., and Toner, M. Label-Free Microfluidic Apheresis of Circulating Tumor Cell Clusters. Advanced Science, 2024; 11, 2405853. DOI


Zhan L, Han Z, Shao Q, Etheridge ML, Hays T, Bischof JC. Rapid joule heating improves vitrification based cryopreservation. Nature Communications. 2022; 13(1):6017. DOI


Zhan L, Rao JS, Sethia N, Slama MQ, Han Z, Tobolt D, et al. Pancreatic islet cryopreservation by vitrification achieves high viability, function, recovery and clinical scalability for transplantation. Nature Medicine. 2022; 28(4):798-808. DOI


Zhan L, Li M-G, Hays T, Bischof J. Cryopreservation method for Drosophila melanogaster embryos. Nature Communications. 2021; 12(1):1-20. DOI


Zhan L, Guo S-Z, Kangas J, Shao Q, Shiao M, Khosla K, et al. Conduction cooling and plasmonic heating dramatically increase droplet vitrification volumes for cell cryopreservation. Advanced Science. 2021; 8(11):2004605. DOI


Liu Y, Zhan L, Qin Z, Sackrison J, Bischof JC. Ultrasensitive and highly specific lateral flow assays for point-of-care diagnosis. ACS Nano. 2021; 15(3):3593-611. DOI


Zhan L, Guo S-Z, Song F, Gong Y, Xu F, Boulware DR, et al. The role of nanoparticle design in determining analytical performance of lateral flow immunoassays. Nano Letters. 2017; 17(12):7207-12. DOI