Assistant Professor of Biomedical Engineering
Sarah Calve received her B.S. in materials science and engineering at Cornell University, and earned both an M.S. degree in molecular, cellular and developmental biology and a Ph.D. in macromolecular science and engineering from the University of Michigan. Her doctoral thesis was titled “Morphological and Mechanical Characterization of Self-Assembled Tendons and Myotendinous Junctions.”
During her graduate research, she developed a 3D, in vitro model of tendon comprised solely of primary tendon cells and the extracellular matrix they secreted. In order to accurately determine the stress-strain response it was necessary for her to build instrumentation that measured strain optically while simultaneously recording force data. Her postdoctoral research has focused on characterizing the influence of extracellular matrix remodeling during musculoskeletal regeneration and repair. She holds two patents for her muscle and tendon remodeling methods.