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Dr. Dianne Little

Areas of Research: Tendon Tissue Engineering, Osteoarthritis, Tendinopathy, Systemic modulators of Musculoskeletal Disease

Projects:

  • Engineered Tendon Development, interactions of social stress and diet on development of post-traumatic osteoarthritis

Our overall goal is to ensure the long-term success of regenerative medicine approaches to treat musculoskeletal disease once clinical translation to the general population becomes a reality. Thus, our research interests lie at the intersection of tissue engineering, integrated 'multiomics' and musculoskeletal biology.

We develop and test novel biomaterials and engineering parameters for their potential application in tendon tissue engineering, and evaluate both intrinsic and extrinsic environmental factors to determine how they modify underlying musculoskeletal disease processes (osteoarthritis, tendinopathy) and ultimately how these factors influence translation of regenerative medicine approaches. Success is defined when we can bring a musculoskeletal implant to a long-term physiological function across a diverse patient population. 

Recruitment Needs: 

  • Looking for one or two highly motivated PhD student in the area of tissue engineering and musculoskeletal biology

 

Please feel free to contact Dr. Little directly
Email: little33@purdue.edu