Recent publication: Han Shih, Hung-Yi Liu, Chien-Chi Lin, "Improving gelatation efficiency and cytocompatability of visible light polymerized thiol-norbornene hydrogen via addition of soluble tyrosine" Biomater. Sci. (2017).
Recent publication: M. Jane Brennan, Bridget F. Kilbride, Jonathan J. Wilker, Julie C. Liu, "A bioinspired elastin-based protein for a cytocompatible underwater adhesive," Biomaterials (2017).
Recent publication: Alexa A. Yrineo, Amelia R. Adelsperger, Abigail C. Durkes, Matthew R. Distasi, Sherry L. Voytik-Harbin, Michael P. Murphy, and Craig Goergen , "Murine ultrasound-guided transabdominal para-aortic injections of self-assembling type I collagen oligomers," Journal of Controlled Release (2017).
Recent publication: Morphological Transformation and Force Generation of Active Cytoskeletal Networks. TC Bidone, W Jung, D Maruri, C Borau, RD Kamm, T Kim - PloS, 2017.
Recent publication: Effects of Loading Duration and Short Rest Insertion on Cancellous and Cortical Bone Adaptation in the Mouse Tibia. H Yang, RE Embry, RP Main - PloS one, 2017.
A Weldon School of Biomedical Engineering-affiliated startup, GeniPhys, has attained Second-Tier Gold Award status from the Elevate Purdue Foundry Fund and will receive $80,000 in funding to advance its efforts.
T.J. Puls (Sherry Harbin, advisor) received a 2017 International Foundation for Ethical Research Graduate Fellowship for Alternatives to the Use of Animals in Science.
Rucha Joshi (Sherry Harbin, advisor) graduated in December 2016 and accepted a position as post-doctoral research assistant at Purdue's Weldon School of Biomedical Engineering.
Heui Chang Lee (Kevin Otto/Kinam Park, co-advisors) graduated in December 2016.
Eric Nauman, professor of biomedical engineering, mechanical engineering, and basic medical sciences, has been inducted into the Purdue University Teaching Academy.
A new tumor model has been shown to predict how certain types of cancer cells react differently to a commonly used chemotherapy drug, a potential tool for "precision medicine," in which drug treatment is tailored to individual patients and certain cancer types.
Engineered Biomaterials & Biomechanics
Biomaterials research focuses on how natural and synthetic materials interact with biological systems. These range from the inert materials used to replace entire joints to biomimetic scaffolds that restore functionality by promoting the body to regenerate the lost tissue. Research at the Weldon School of Biomedical Engineering covers all facets of this exciting area. From advanced studies characterizing the instructive role of extracellular matrix components, to developing novel polymeric biomaterials, researchers and students are finding new ways to replace, repair, or regenerate tissues lost or damaged from injury and disease.
Critical parameters that inspire biomaterial and implant design are the mechanical environment into which it will be placed and how cells sense and respond to mechanophysical cues, otherwise known as mechanobiology. By studying the strengths and weaknesses of individual tissue components, researchers are improving not only our understanding of the body, but also the devices needed to repair the body. Biomechanics research at the Weldon School spans experimental and computational design at multiple length scales, including studies into how external forces impact the body as a whole all the way down to quantifying how subcellular deformations influence gene expression.
The interdisciplinary team at the Weldon School of Biomedical Engineering is building on a solid foundation of accomplishment. From studies that can detect microfractures in bones before they can evolve into a problem, to advanced implants that monitor themselves and the environment around them, researchers are developing the knowledge and clinical treatments that will change the way we view and repair the body.