Medical Imaging Diagnostic Technologies
Learning Objective:The goal is to have the students master the universal principles and ideas rather than a smattering of individual techniques.
This gateway course will provide an introduction to the physics, technologies, and biological considerations associated with modern imaging and diagnostic tools. Specific modalities to be examined will include x-ray, nuclear imaging, ultrasound, MRI, and microscopy techniques such as phase contrast, DIC, confocal microscopy, two-photon microscopy as well as concept of adaptive optics, light-sheet microscopy, 4Pi microscopy, and modern super-resolution microscopy techniques (PALM/STORM, STED and IM). The course also covers principles of optics, contrast generation (including genetically encoded probes and physiological indicators), image formation, detection, and analysis.
Overview/Math Foundations/Energy-Matter Interactions.
Physiological Limitations of Energy Exposure.
Projection Tomographic Concepts (X-ray/CT).
Emission Tomographic Concepts (PET/SPECT).
Reflection Tomography (US/Optical).
Diffusion Tomographic Concepts (Optical).
Resonance Tomographic Concepts (MRS/MRI).
In addition, through guest lectures (GL), we will hear the recent research progresses and corresponding biomedical applications in areas such as OCT, ultrasound, MRI, fluorescence microscopy, electron microscopy, concurrent MRI and optical functional imaging, and Coherent anti-Stokes Raman spectroscopy.
This course also includes a crash sub-course on MATLAB programming including both introductory content and contents of MATLAB-C API and MATLAB-C-CUDA (GPU computing).