June 28, 2025
Purdue Sleep and Developmental Studies Lab uncovers potentially eye-opening link between sleep and Alzheimer's
Purdue's Sleep and Developmental Studies Lab, led by A.J. Schwichtenberg, has uncovered a potentially pivotal connection between N2 deep sleep and the brain's ability to clear metabolic waste - a process that may be key in preventing Alzheimer's disease. Using MRI and 36-channel EEG data from adults aged 30-55, the team found that cerebrospinal fluid "sloshing" during N2 sleep begins clearing debris earlier in the night than previously believed. The interdisciplinary study includes Yungie Tong from Purdue's Weldon School of Biomedical Engineering, highlighting the role of BME in advancing sleep and brain health research.