Neural Mechanisms of Health and Disease
Learning Objective:1. Describe the organization of the mammalian nervous system and to some degree how it compares to non-mammalian nervous systems. 2. Apply neural information processing principles to determine how external and internal variables drive neural activity and behavior. 3. Design experiments by selecting appropriate techniques and measurements in order to address an experimental question or hypothesis. 4. Analyze and interpret neural data, mainly neurophysiological data, to answer questions about neural coding and with respect to an experimental hypothesis. 5. Develop preliminary therapeutic solutions to neural disorders based on understanding neural mechanisms and devices used to measure or treat these disorders
This is a new distance course offering.
Spring 2015 Syllabus
Topics Covered:Introduction: Levels of organization; Review of basic neuronal elements and signaling; Single neuron plasticity and computation; Organization of nervous system; Analysis of neuroanatomy data; Sensory transduction: Physical and chemical senses; Feature extraction of sensory information; Higher order sensory processing; From sensory coding to perception; Motor coding; Sensorimotor integration; Sensorimotor integration; Higher cognition; When brains attack: Neural disorders and neurodegeneration.
Prerequisites:Graduate standing or permission of instructor.
Applied / Theory:
Web Content:Lecture slides, syllabus, problem set answers, lecture recording and useful resources.
Homework:20% of the grade is based on assignments/participation. firstname.lastname@example.org
Projects:There is a research grant proposal, report and final presentation as well as a project on neural coding. Further details will be provided during the semester.
Exams:1 midterm exam, 1 take-home midterm and 1 take-home final
Textbooks:Official textbook information is now listed in the Schedule of Classes. Required:
-From Neuron to Brain, 5th Edition by John G. Nicholls, Sinauer Associates, Inc. ISBN:9780878936090
-Fundamental Neuroscience, 4th Edition by Larry Squire, Academic Press, ISBN:B00AC1EGXE
-MATLAB for Neuroscientists: An Introduction to Scientific Computing in MATLAB, 1st Edition by Pascal Wallisch, Academic Press, ISBN:9780123745514
-Principles of Neural Science, 5th Edition by Eric Kandel, McGraw-Hill Education/Medical ISBN:B009LHFYNG
-Spikes: Exploring the Neural Code (Computational Neuroscience) by Fred Rieke ISBN:9780262681087