The Architecture of Thought

Submitted by: Cheng Bi

Category: Microscopy

Creation: Super-resolution reconstruction of a mouse brain sample injected with Brainbow virus, immunolabeled with anti-GFP antibody conjugated to AF647, and imaged using a biplane system.

Caption: This artwork highlights the dendritic spine structures of a mouse neuron, which often appear blurred under conventional imaging. Through Brainbow labeling, anti-GFP-AF647 staining, and biplane super-resolution microscopy, these fine synaptic details are resolved with exceptional clarity.