Andrew O. Brightman

As the Assistant Head for Academic Affairs for the Weldon School of Biomedical Engineering Andrew has overseen the development of both the undergraduate and the graduate curriculum and participated in the design and teaching of many of the courses. Within his ten years of administrative and teaching experience at Purdue Andrew has developed numerous undergraduate and graduate courses including the sophomore, junior, and senior-level professional development and design courses.  Andrew has participated regularly in team-teaching in two courses that use interactive learning structure and has co-taught for 5 years a graduate–level course in Biomedical Engineering Ethics, which uses a similar case-study based approach. In addition, Andrew has developed a curriculum for our new Professional MS degree with a concentration in regulatory affairs for medical devices. The concentration includes three courses covering the key areas and documentation involved with pre-clinical and clinical studies, regulatory approval, and regulatory compliance. Currently, Andrew is co-creating a new course in clinical and translational research ethics to support our joint MSTP training program with the Indiana University School of Medicine, for which he serves on the Steering Committee. 

Andrew’s research background and interests include a background in analysis of signaling biomolecules and tissue engineering in which he contributed to the research and development of the Small Intestinal Submucosa (SIS) technology at Purdue University and with a partner company in the Purdue Research Park. Through this experience Andrew gained knowledge about biomedical technology innovation and translation, which has helped to build the foundation from which he is able to contribute to engineering design, regulatory affairs, and ethical practice. Andrew’s current research in ethics investigates a new pedagogy for training engineering students in ethical reasoning. Andrew leads a multidisciplinary team from Engineering Education, Materials Science Engineering, Philosophy, and Communication that is studying a hybrid course delivery model that involves a scaffolded, integrated, reflective analysis of historical cases and cases dealing with emerging technology from a reflexive principlism approach. Andrew is also working on developing a mouse model of chronic stress for the development of novel biomarkers for the healthcare of children.



Urinary bladder submucosa derived tissue graft
SF Badylak, SL Voytik, A Brightman, M Waninger - US Patent 5,554,389, 1996

Stomach submucosa derived tissue graft
SF Badylak, SL Voytik-Harbin, AO Brightman… - US Patent 6,099,567, 2000

Submucosa as a growth substrate for cells
SL Voytik-Harbin, AO Brightman, RM Meixner… - US Patent 6,264,992, 2001

Submucosa gel compositions
SL Voytik-Harbin, AO Brightman, RM Meixner… - US Patent 6,444,229, 2002

Submucosa extracts
SF Badylak, AO Brightman, JP Hodde, TB McPherson… - US Patent 6,375,989, 2002

Submucosa gel compositions
SL Voytik-Harbin, AO Brightman, RM Meixner… - US Patent 7,147,871, 2006

Growth factor modified extracellular matrix material and methods for preparation and use thereof
MC Hiles, A Brightman, AD Janis - EP Patent 2,150,283, 2010