Biography

Andrew O. Brightman

Andrew O. Brightman is the Assistant Head for Academic Affairs and Associate Professor of Engineering Practice in the Weldon School of Biomedical Engineering at Purdue University, West Lafayette, Indiana, U.S.A. Professor Brightman attended North Carolina State University, Raleigh, North Carolina, where he received the B.S. degree in Botany and Plant Physiology. He then attended Purdue University, West Lafayette, Indiana, and received the Ph.D. degree in Cell Biology and Biochemistry.  Upon completion of his doctoral studies, Professor Brightman completed two post-doctoral fellowships in Medicinal Chemistry, at Purdue University, and in Cancer Biotechnology, at Eli Lilly & Co, Indianapolis, Indiana. Professor Brightman then joined the Hillenbrand Biomedical Engineering Center as a Senior Research Scientist in Tissue Engineering where he contributed to the research and development of the tissue engineered small intestinal submucosa (SIS) technology.  Professor Brightman also has worked as an independent consultant for several medical technology companies. Through these professional experiences, education and research background in analysis of signaling biomolecules and tissue engineering, Professor Brightman has gained knowledge about biomedical technology innovation and translation and built a foundation from which he is able to contribute to engineering design, regulatory affairs, and ethical practice.

Professor Brightman’s current research in engineering education investigates a new pedagogy for training engineering students in ethical reasoning. He leads a multidisciplinary team from Engineering Education, Materials Science and Electrical and Computer Engineering, Philosophy, and Communication that has developed a hybrid course delivery model that involves a scaffolded, integrated, reflective analysis (SIRA) of historical cases and cases dealing with emerging technology from a Reflexive Principlism (RP) approach and is studying the ethical experiences of practicing engineers in the health products industry.

As the Assistant Head for Academic Affairs for the Weldon School of Biomedical Engineering Professor Brightman has overseen the development of both the undergraduate and the graduate curricula and participated in the design and teaching of many of the core courses. Within his 15 years of administrative and teaching experiences at Purdue he has served as chair of both of the undergraduate and graduate curriculum committees and he developed numerous undergraduate and graduate courses in biomedical engineering, including the sophomore, junior, and senior-level professional development and design courses.  Professor Brightman also developed and has co-taught for 10 years with an engineering alumnus from the medical device industry, a graduate–level course in Biomedical Engineering Ethics, which uses a novel pedagogical approach to analyzing ethical issues in the design, development, and deployment of medical technologies. In addition, Professor Brightman has developed the curriculum for the Professional MS BME degree with a concentration in regulatory affairs for medical devices. The concentration includes three courses covering the key aspects involved with pre-clinical and clinical studies, regulatory approvals, and regulatory compliance. Each of these courses he developed in partnership with industry colleagues for real-world relevance and impact. Currently, Professor Brightman also serves on multiple NIH training grants in the School with oversight of the educational components as co-director of the Scholarly Concentration in Biomedical Engineering and Applied Medical Technologies administered jointly with the Indiana University School of Medicine and as the Director of the NIH TL1 pre-doctoral program for the Indiana Clinical Translational Science Institute.   Professor Brightman has been awarded the Outstanding Leadership Award from the Purdue College of Engineering.  

Patents

Urinary bladder submucosa derived tissue graft
SF Badylak, SL Voytik, A Brightman, M Waninger - US Patent 5,554,389, 1996

Stomach submucosa derived tissue graft
SF Badylak, SL Voytik-Harbin, AO Brightman… - US Patent 6,099,567, 2000

Submucosa as a growth substrate for cells
SL Voytik-Harbin, AO Brightman, RM Meixner… - US Patent 6,264,992, 2001

Submucosa gel compositions
SL Voytik-Harbin, AO Brightman, RM Meixner… - US Patent 6,444,229, 2002

Submucosa extracts
SF Badylak, AO Brightman, JP Hodde, TB McPherson… - US Patent 6,375,989, 2002

Submucosa gel compositions
SL Voytik-Harbin, AO Brightman, RM Meixner… - US Patent 7,147,871, 2006

Growth factor modified extracellular matrix material and methods for preparation and use thereof
MC Hiles, A Brightman, AD Janis - EP Patent 2,150,283, 2010