Linnes Lab – Jacqueline Linnes

Leading a diverse and inclusive research lab developing translational point-of-care diagnostics for global health and underserved US populations. Fundamental microfluidic principles applied to biological assays are utilized to generate advances in paper microfluidics and molecular biosensors.

Technologies in the lab are created with human-centered design principles that include design, development and testing in collaboration with stakeholders and end-users of the technologies in actual use settings.

Key Areas of Research:

• Paper-based diagnostics: Generating fundamental insights into fluid of transport in porous membranes to engineer novel paper fluidic platforms for pathogen detection at the point of care.

• Nucleic-acid Biosensors: Designing more accessible highly-sensitive assays that use nucleic acid aptamers and amplification to detect viral and bacterial pathogens.

• Wearable Biomolecular Detection: Developing integrated technologies for collecting and detecting analytes in interstitial fluid to monitor stress and mental health over time.

• Human-Centered Design: Proactively evaluating and overcoming barriers to equitable design and implementation of point-of-care diagnostics by working hand-in-hand with community partners and clinician and patient stakeholders.

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