Abstract:

The evolution of Michigan neural probe technologies will be reviewed toward scaling up the number of recording sites and adding selective neural modulation capability to enable optogenetic control of neurons at cellular resolution. Multiple neuro-size micro-LEDs (~10 μm) were monolithically integrated on a probe shank to achieve high spatial temporal modulation of neural circuits. Initial prototype optoelectrodes (MiniSTAR) demonstrated independent control of distinct neuron cells ~50 μm apart in the CA1 pyramidal layer of freely-moving mice at 60 nW light power. The number of optical stimulation sites has scaled up to integrate 128 micro-LEDs along with 256 recording sites (HectoSTAR). Recently, 3D origami architecture has been introduced to deploy the optoelectrodes on non-planar surfaces and enable multi-modalities by incorporating the additional sensors to monitor neurotransmitters and temperature of the local brain region and their effects on electrophysiology.

Biography:

Euisik Yoon is a professor in the Department of Electrical Engineering and Computer Science at the University of Michigan, Ann Arbor. After receiving PhD degree in Electrical Engineering from the University of Michigan, Ann Arbor, he worked for industry including the National Semiconductor Corp. in Santa Clara, CA and Silicon Graphics Inc. in Mountain View, CA before returning to academia (1990-1996). He took faculty positions at Korea Advanced Institute of Science and Technology (KAIST) in Daejon, Korea and the University of Minnesota, Minneapolis, MN, respectively. In 2008, he joined the University of Michigan, Ann Arbor, MI, where he is a Professor. He served as the Director of Solid-State Electronics Laboratory (2011-2015) and the Director of Lurie Nanofabrication Facility (2011-2016) at the University of Michigan. He led the NSF NeuroNex Hub: Multimodal Integrated Neural Technologies (MINT), disseminating neurotechnologies to the research community (2017-2024). He also served as the Director of NSF International Program for the Advancement of Neurotechnology (IPAN) (2015-2024).

Yoon has served on various Technical Program Committees including the IEEE International Electron Device Meeting (IEDM) (2006-2008) and the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) (2006, 2008-2010, 2021). He also served on the IEEE International Solid-State Circuit Conference (ISSCC) program committee (2003-2007) and organized and co-chaired the International Conference for Advanced Neurotechnology (ICAN) (2016-2020). He served as an associate editor for IEEE Solid-State Circuit Letters (2018-2021).

~ BME Host: Krishna Jayant ~

Zoom Link: https://us02web.zoom.us/j/88907615893?pwd=Ema0Jd4Hkp2lbJ30xkuCL5dwuGysob.1

Students registered for the seminar are expected to attend in-person.

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