Diabetes Research Centers Virtual Seminar Series - Wednesday, February 9

Event Date:	February 9, 2022

Frances Ashcroft, DBE, FRS, FMedSci, Professor, Department of Physiology, Anatomy and Genetics, Oxford University

Frances Ashcroft, DBE, FRS, FMedSci, Professor, Department of Physiology, Anatomy and Genetics at Oxford University will present a virtual seminar on Wednesday, February 9 at 2:00 p.m. entitled "Metabolic regulation of insulin secretion in health and disease."

Please register at:   https://redcap.link/DRCVirtualSeminarSeries-FrancesAshcroft 

The  ATP-sensitive potassium (KATP) channel plays a critical role in insulin secretion by coupling metabolism to electrical activity. This lecture discusses how mutations in KATP channel genes that impair its metabolic regulation lead to disorders of insulin secretion like neonatal diabetes and congenital hyperinsulinism. It also shows how chronic hyperglycaemia impairs beta-cell metabolism and thereby KATP channel closure and insulin secretion, leading to a vicious spiral that drives the progression from impaired glucose tolerance to diabetes. 

The Virtual Seminar Series is sponsored by the Diabetes Research Centers and Centers for Diabetes Translational Research.  Questions, feedback, or suggestions for future speakers?   Contact us at: virtual.seminar.series@vumc.org   

More information can be found here: https://www.vumc.org/diabetescenter/virtual-seminar-series  

2022-02-09 08:00:00 2022-02-09 17:00:00 America/Indiana/Indianapolis Diabetes Research Centers Virtual Seminar Series - Wednesday, February 9 Frances Ashcroft, DBE, FRS, FMedSci, Professor, Department of Physiology, Anatomy and Genetics at Oxford University will present a virtual seminar on Wednesday, February 9 at 2:00 p.m. entitled "Metabolic regulation of insulin secretion in health and disease." Purdue University