Elias I. Franses
Professor of Chemical Engineering
School of Chemical Engineering
Forney Hall of Chemical Engineering
480 Stadium Mall Drive
West Lafayette, IN 47907-2100
In one project, with Professor Nien Hwa Linda Wang, on "Experimental Probing and Molecular Simulations of Key Sorbent-Solute-Solvent Interactions in Chiral Separations," we study how ultrathin films of some polysaccharide-based polymers at solid interfaces can "recognize" and separate in chromatographic columns racemic mixtures of enantiomers, which otherwise they have identical physical and chemical properties. We use IR spectroscopy, x-ray diffraction, solid-state NMR, and advanced molecular modeling. Understanding and quantitative modeling of sorbent/solute/solvent interactions should allow for non-empirical selection of solvents and sorbents for specific industrial separations of many chiral pharmaceuticals, and may lead to devising sorbents of optimal molecular structures.
In a second project, in collaboration with Professor David S. Corti, we study the "Aqueous Dispersion Stability of Inks and Ink-Like Model Colloidal Dispersions." The main goal of the detailed experimental and theoretical studies is to improve understanding of the inter-particle forces which cause the dispersions of colloidal particles or nanoparticles to agglomerate, or to remain stable. The project may lead to innovative theories, models, and simulations, and industrial guidelines on how to control dispersion stability, and ultimately to new ways of making improved inks. In addition, we study the colloidal stability of dispersions of hydrates particles formed by complexes of hydrocarbons and water. Such hydrates may lead to plugging of pipelines containing hydrocarbons during the production stages, and should be avoided.
- Mr. Aniruddha Kelkar (with Prof. David S. Corti)
- Mr. Hung-Wei Tsui (with Prof. Nien-Hwa Linda Wang)
- Ms. Betty Yung-Jih Yang (with Prof. David S. Corti)
Awards and Honors
“Mechanistic Studies of Chiral Discrimination in Polysaccharide Phases;” H-W. Tsui, R. B. Kasat, E. I. Franses, and N.-H. L. Wang, Advances in Chromatography Series, 50, 47-91, (2012) Eli Grushka and Nelu Grinberg, Editors; CRC Press, Taylor and Francis, Boca Raton, FL (2012)
”Effect of Triton X-100 on the Dispersion Stability of Aqueous Dispersions of Copper Phthalocyanine Pigment Nanoparticles,” J. Dong, S. Chen, D. S. Corti, E. I. Franses, H. T. Ng, Y. Zhao, and H. Hanson, J. Colloid Interf. Sci, 362(1), 33-41 (2011)
”Adsorption of Myrj 45 on Copper Phthalocyanine Pigment Nanoparticles and Effect on the Dispersion Stability in Aqueous Solution,” J. Dong, D. S. Corti, E. I. Franses, Y. Zhao, H. T. Ng, and E. Hanson, Colloids Surf. A, 390, 74-85 (2011)
“InfraredSpectroscopy (IR) and Molecular Simulations of a Polymeric Sorbent and Its Enantioselective Interactions with Benzoin Enantiomers,” H-W. Tsui, R. Kasat, J. Willing, N.-H. L. Wang, and E. I. Franses, J. Phys. Chem. B, 115 (44), 12785-12800 (2011)