Department of Agricultural & Biological Engineering
225 South University Street
West Lafayette, IN 47907-2093
- Biological Engineering
My lab focuses on microscopy, image analysis, and finite-element computer modeling to elucidate mechanisms of BMP regulation by developing organism- and tissue-scale, data-driven models of Drosophila embryos, Xenopus embryos, and the epithelial layers of the Drosophila wing imaginal disc. While there is no substitute for hypothesis testing by experimentation, the organism-scale models provide a new methodology to conduct large-scale screens to test plausible regulatory mechanisms and identify conditions that lead to easily discernable phenotypes. We are uniquely capable of developing the models, conducting the model-driven screens, and testing the model predictions by experimentation and biological imaging.
Publication reprints available upon request.