Nancy W. Ho
Emeritus Research Professor of Chemical Engineering
School of Chemical Engineering
Forney Hall of Chemical Engineering
480 Stadium Mall Drive
West Lafayette, IN 47907-2100
Awards and Honors
Xie, Y., Phelps, D., Lee, C. H., Sedlak, M., Ho, N.W. Y., and L. N. H. Wang, "Comparison of Two Adsorbents for Sugar Recovery from Biomass Hydrolyzate," Ind. Eng. Chem. Res. 44: 6816-6823, 2005.
Mosier, N. S., Hendrickson, R., Brewer, M., Ho, N. W. Y., Sedlak, M., Dreschel, R., Welch, G., Dien, B. S., Aden, A., and M. R. Ladisch, "Industrial Scale-up of pH-controlled liquid hot water pretreatment of corn fiber for fuel ethanol production," Applied Biochemistry and Biotechnology, 125, 77-85, 2005.
Sedlak, M. and N. W. Y. Ho, "Characterization of the effectiveness of hexose transporters for transporting xylose during glucose and xylose co-fermentation by a recombinant Saccharomyces yeast," Yeast 21:671-684, 2004.
Sedlak, M. and N. W. Y. Ho, "Production of ethanol from cellulosic biomass hydrolysate using genetically engineered Saccharomyces yeast capable of co-fermenting glucose and xylose," Appl. Biochem. Biotech. 113-116: 403-416, 2004.
Ho, N. W. Y., "The logical design and development of genetically engineered yeast for effective conversion of plant cellulosic biomass to ethanol," Chinese Americans in Science and Technology 85-132, Outer Sky Press, New York, 2003.
Sedlak M, Edenberg H.J. and N. W. Y. Ho, "DNA microarray analysis of the expression of the genes encoding major enzymes in ethanol production during glucose and xylose co-fermentation by metabolically engineered Saccharomyces yeast," Enzyme. Microbial. Technol. 33:19-28, 2003.
D. Sliva, C. Labarrere, V. Slivova, M. Sedlak, F. P. Lloyd Jr., and N. W. Y. Ho, "Ganoderma lucidum suppresses motility of highly invasive breast and prostate cancer cells," BBRC. 298, 603-612, 2002.
Sedlak, M., and N. W. Y. Ho, "Expression of E. coli araBAD operon encoding enzymes for metabolizing L-arabinose in Saccharomyces cerevisiae," Enzyme and Microbial Technology, 28 , 16-24, 2001.
Ho, N. W. Y., Chen, Z., Brainard, A. P., and M. Sedlak, Chapter 12 in ACS Symposium Series 767, "Genetically engineered Saccharomyces yeasts for conversion of cellulosic biomass to environmentally friendly transportation fuel ethanol," Amer Chem Society, 142-159, 2000.
Ho, N. W. Y., Chen, Z., Brainard, A. P., and M. Sedlak, "Successful design and development of genetically engineered Saccharomyces yeasts for effective cofermentation of glucose and xylose from cellulosic biomass to fuel ethanol," Advances in Biochemical Engineering/Biotechnology, 65 , 163-192, 1999.
Ho, N. W. Y., Chen, Z., and A. Brainard, "Genetically Engineered Saccharomyces yeast capable of effective cofermentation of glucose and xylose," Appl Environ. Microbiol, 64 , 1852-1859, 1998.
Toon, S. T., Philippidis, G. P., Ho, N. W. Y., Chen, Z., Brainard, A., Lumpkin, R. E., and C. J. Riley, "Enhanced cofermentation of glucose and xylose by recombinant Saccharomyces yeast strains in batch and continuous operating modes," Appl. Biochem. and Biotech., 63-65 , 243-255, 1997.
Moniruzzaman, M., Dien, B. S., Skory, C. D., Chen, Z. D., Hespell, R. B., Ho, N. W. Y., Dale, B. E., and R. J. Bothast, "Fermentation of corn fibre sugars by an engineered xylose utilizing Saccharomyces yeast strain," World Journal of Microbio & Biotechno, 13 , 341, 1997.
Cao, N. J., Krishnan, M. S., Du, J. X., Chen, Z. D., Gong, C. S., Ho, N. W. Y. and G. T. Tsao, "Ethanol production from corn cob pretreated by the ammonia steeping process using genetically engineered yeast," Biotechnology Letters, 18, 1013-1018, 1996.
Ho, N. W. Y., and S. F. Chang, "Cloning of yeast xylulokinase gene by complementation of E. Coli and yeast mutations," Enzyme Microb. Technol., 11 , 417-421, 1989.
Stevis, P. E. and N. W. Y. Ho, "Construction of yeast xylulokinase mutant by recombinant DNA techniques," Appl. Biochem. Biotechnol., 20 (21), 327-334, 1989.
Chang, S. F. and N. W. Y. Ho, "Cloning the yeast xylulokinase gene for the improvement of xylose fermentation," Appl. Biochem. and Biotechnol., 17, 313-318, 1988.
Rosenfeld, S., Stevis, P., Tsao, G. T., and N. W. Y. Ho, "Genetic characterization of the xylose utilization genes of E. coli ," Mol. Gen. Genetics, 410-415, 1984.
Stevis, P. E., Huang, J. J., and N. W. Y. Ho, "Cloning of the Pachysolen tannophilus xylulokinase gene by complementation in Escherichia coli," Appl. Environ. Microbiol., 53(12), 2975-2977, 1987.
Stevis, P. E. and N. W. Y. Ho, "Overproduction of D-Xylose isomerase in E. coli by cloning the D-Xylose isomerase gene," Enzyme Microbial Technology, 7, 592-596, 1985.
Rosenfeld, S., Stevis, P., Tsao, G. T., and N. W. Y. Ho, "Genetic characterization of the xylose utilization genes of E. coli," Mol. Gen. Genetics, 410-415, 1984.
Patents Related to Genetic Engineering of Yeasts for New Industrial ApplicationsHo, N. W. Y. and M. Sedlak, "Development of Stable Genetically Engineered Yeast for Industrial Conversion of Sugars from Glucose-Based and Glucose-Xylose- Based Feedstocks to Lactic Acid", patent pending.
Ho, N. W. Y, and Z. D. Chen, "Stable Recombinant Yeasts Capable of Effective Fermentation of Both Glucose and Xylose." Patent Application, #60/016, 865, May 6, 1996. PCT Patent No. WO97/42307, November 13, 1997. This application has been allowed in Australia before March, 2001 but pending everywhere else including US.
Ho, N. W. Y and G. T. Tsao, "Recombinant Yeasts for Effective Fermentation of Glucose and Xylose," PCT Patent No. W095/13362, (1995); the patent was allowed in the US on Aug. 4, 1998, patent No. 5,789,210.