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Seminars in Hearing Research at Purdue (SHRP)

Title:  Effects of Training and Corticofugal Modulation on Startle Behavior and Auditory Physiology

Speaker(s): Edward Bartlett/Marisa Dowling

Date: Apr 25, 2019
Time: 10:30 – 11:20 am
Location: LYLE 1150

Abstract:

As languages utilize noisy time varying frequency trajectories, also known as pitch sweeps, to convey speech information, it is important to understand the impacts of training as a potential means to preserve noisy pitch sweep processing with aging, for example. In addition, it is unclear which circuit elements may mediate training-related changes. We hypothesize that top-down feedback via corticocollicular modulation may be involved.  Neuromodulation, specifically pharmacogenetics, can be used to inhibit the neural pathway of interest to determine the significance of its role in complex speech processing. The consequences of training and A1-IC pathway inhibition were investigated using behavioral and electrophysiological measurements. Behavioral noisy time varying pitch sweep discrimination abilities were measured using prepulse inhibition of acoustic startle response. Electrophysiological measurements of brain activities were assessed by envelope following responses (EFR).

The working schedule for this semester is here:

https://purdue.edu/TPAN/hearing/shrp_schedule

The titles and abstracts of the talks will be updated here:

https://purdue.edu/TPAN/hearing/shrp_abstracts