Seminars in Hearing Research at Purdue (SHRP)

Date: Thursday, September 1, 2022

Time: 10:30 – 11:20 am

Location: LYLE 1150

Speaker: Andrew Sivaprakasam, MD/PhD (MSTP) program, Weldon School of Biomedical Engineering

Title:  Differential Profiles of SNHL Variably Impact Neural Coding of Modulations and Pitch: Recent Findings and Planned Future Study

Abstract:

Sensorineural Hearing Loss (SNHL) can be the result of several etiologies and a major goal of modern hearing research is to reliably identify specific profiles of hearing loss to better individualize therapies and hearing-assistive technology. Specifically, those who report hearing loss likely have variable patterns in cochlear anatomic damage– be it damage to the inner hair cells, outer hair cells, or cochlear synapse. Therefore, it is critical we identify the physiological consequences of these patterns of damage and how they lead to perceptual deficits. It is known SNHL degrades the ability to discriminate pitch, the cue we depend on to properly identify voices or listen to music. However, it is not known how IHC, OHC, and cochlear synapse damage specifically contribute to this deficit. I will first present our recent findings which indicate that IHC damage and cochlear synaptopathy differentially impact neural coding of modulations and pitch in chinchillas. I will then share some preliminary data and analyses demonstrating my planned approach to link pitch discrimination deficits to abnormalities in audiological and electrophysiological measures across species.

Zoom Info: https://purdue-edu.zoom.us/j/4326340458

Meeting ID: 432 634 0458

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The working schedule for this academic will be here:

https://purdue.edu/TPAN/hearing/shrp_schedule

The titles and abstracts of the talks will be added here:

https://purdue.edu/TPAN/hearing/shrp_abstracts