Experiments conducted by NASA measured the pressure drop due to gas-liquid flow through a packed-bed reactor under microgravity conditions. From these experiments, we develop correlations for the gas-liquid f_gl interphase drag in a two-fluid model (TFM). We use an Ergun-type closure for liquid-solid drag. Then, under a 1D flow assumption, f_gl is the only unknown in the TFM. Using a data-driven approach, we determine f_gl and correlate it (via composite fits) with the liquid and gas Reynolds numbers, Re_l and Re_g, respectively, and the Suratman number Su_l. To validate the proposed f_gl(Re_l, Re_g,Su_l) closure, we perform two-dimensional transient simulations at microgravity conditions using ANSYS Fluent and employing an Euler-Euler formulation. We find good agreement between the simulations based on the proposed f_gl closure and the experimental data.