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Joaquín Goñi

School of Industrial Engineering
Purdue University
Grissom Hall Room 368
315 North Grant Street
West Lafayette, IN 47907
office: (+1) 765-494-7198
cell: (+1) 812-650-2688
jgonicor@purdue.edu

• Research Gate: www.researchgate.net/profile/Joaquin_Goni/

• Google Citations: http://scholar.google.com/citations?user=K3bp04sAAAAJ&hl=en

• LinkedIn: https://www.linkedin.com/pub/joaqu%C3%ADn-go%C3%B1i/10/ba6/aa3

Affiliations:

Papers: Published/in press/accepted papers (citations according to Scopus database)

49. Path ensembles and a tradeoff between communication efficiency and resilience in the human connectome (2016). Avena-Koenigsberger, A, Mišić, B, Hawkins, RX, Griffa A, Hagmann P, Goñi J*, Sporns O*. Brain Structure and Function, 1-16. Citations: 0.

48. Generative models of the human connectome (2016). Betzel, R. F., Avena-Koenigsberger, A., Goñi, J., He, Y., de Reus, M. A., Griffa, A., ... & Sporns, O. (2016). NeuroImage, 124, 1054-1064. Citations: 4.

47. The Structural and Functional Connectome and Prediction of Risk for Cognitive Impairment in Older Adults (2015). JA Contreras, J Goñi, SL Risacher, O Sporns, AJ Saykin. Current Behavioral Neuroscience Reports 2 (4), 234-245. Citations: 0.

46. Age gene expression and coexpression progressive signatures in peripheral blood leukocytes (2015). Irizar, H., Goñi, J., Alzualde, A., Castillo-Triviño, T., Olascoaga, J., de Munain, A. L., & Otaegui, D. Experimental gerontology, 72, 50-56. Citations: 0.

45. Nodal centrality of functional network in the differentiation of schizophrenia (2015). Cheng, H., Newman, S., Goñi, J., Kent, J. S., Howell, J., Bolbecker, A., ... & Hetrick, W. P. Schizophrenia research, 168(1), 345-352. Citations: 0.

44. Integrated Visualization of Human Brain Connectome Data (2015). Li, H., Fang, S., Goñi, J., Contreras, J. A., Liang, Y., Cai, C., ... & Shen, L. (2015). Brain Informatics and Health (pp. 295-305). Springer International Publishing.

43. Cooperative and competitive spreading dynamics on the human connectome (2015). B Misic, RF Betzel, A Nematzadeh, J Goñi, A Griffa, P Hagmann, A Flammini, YY Ahn, O Sporns. Neuron 86.6 (2015): 1518-1529. Citations: 0.

42. Dopaminergic modulation of the trade-off between probability and time in economic decision-making (2015). G Arrondo, M Aznárez-Sanado, MA Fernández-Seara, J Goñi, FR Loayza, E Salamon-Klobut, FH Heukamp, MA Pastor. European Neuropsychopharmacology 25(6) 817-827. Citations: 0.

41. A network convergence zone in the hippocampus (2015). B Misic, J Goñi, O Sporns, AR McIntosh. PLOS Comp Biol. 10(12) e1003982. Citations: 6.

40. Network morphospace (2015). A Avena-Koenigsberger, J Goñi, RV Solé, O Sporns. Journal of the Royal Société – Interface 12(103) 20140881. Citations: 4.

39. Hubs and Pathways (2014). J Sepulcre, MR Sabuncu, J Goñi. Brain Mapping: An Encyclopedic Reference. 23. Elsevier. Eds M Mesulam and S Kastner. Accepted. Citations: 0.

38. Changes in structural and functional connectivity among resting-state networks across the human lifespan (2014). RF Betzel, L Byrge, Y He, J Goñi, XN Zuo, O Sporns. NeuroImage 102P2:345-357. Citations: 5.

37. Multiscale Integration and Predictability in Resting State Brain Activity (2014). A Kolchinsky, MP van den Heuvel, A Griffa, P Hagmann, LM Rocha, O Sporns, J Goñi. Frontiers in Neuroinformatics – Special Issue “Information-based methods for neuroimaging: analyzing structure, function and dynamics”. 8(66). Citations: 0.

36. Using Pareto Optimality to Explore the Topology and Dynamics of the Human Connectome (2014). A Avena-Koenigsberger, J Goñi, RF Betzel, MP van den Heuvel, A Griffa, P Hagmann, JP Thiran, O Sporns. Phil. Trans. R. Soc. B. 369(1653). Citations: 2.

35. Resting Brain Functional Connectivity Predicted by Analytic Measures of Network Communication (2014). J Goñi  MP van den Heuvel, A Avena-Koenigsberger, N Velez de Mendizabal, RF Betzel, A Griffa, P Hagmann, B Corominas-Murtra, JP Thiran, O Sporns. Proc Natl Acad Sci USA 111(2):833-8. Citations: 56.

34. Multi-scale community organization of the human structural connectome and its relationship with resting-state functional connectivity (2013). RF Betzel, A Griffa, A Avena-Koenigsberger, J Goñi, JP Thiran, P Hagmann, O Sporns. Network Science 1(3):353-373. arXiv: http://arxiv.org/abs/1304.0485. Citations: 0.

33. Predicting Relapsing-Remitting Dynamics in Multiple Sclerosis Using Discrete Distribution Models: a Population Approach (2013) N Velez de Mendizabal, MM Hutmacher, IF Troconiz  J Goñi, P Villoslada, F Bagnato, RR Bies. PLoS ONE 8(9): e73361. Citations: 1.

32. Robust estimation of fractal measures for characterizing the structural complexity of the human brain: optimization and reproducibility (2013). J. Goñi, O. Sporns, H Cheng, M Aznárez-Sanado, Y Wang, S Josa, G Arrondo, VP Mathews, TA Hummer, WG Kronenberger, A Avena-Koenigsberger, AJ Saykin, MA Pastor. NeuroImage 83, 646-657. Citations: 1.

31. On the origins of hierarchy in complex networks (2013) B Corominas-Murtra, J Goñi, RV Solé, C Rodríguez-Caso. Proc Natl Acad Sci USA 110(33):13316-21. Citations: 20.

30. Exploring the Morphospace of Communication Efficiency in Complex Networks (2013) J Goñi, A Avena-Koenigsberger, N Velez de Mendizabal, MP van den Heuvel , R Betzel, O Sporns. PLoS ONE 8(3):e58070. Citations: 10.

29. Abnormal rich club organization and functional brain dynamics in schizophrenia (2013). MP van den Heuvel, O Sporns, G Collin, T Scheewe, RCW Mandl, W Cahn, J Goñi, HE Hulshoff Pol and RS Kahn. JAMA Psychiatry 70(8):783-92. Citations: 58. Paper featured at: From Lichtheim to Rich Club. Brain Networks and Psychiatry (2013). E Bullmore, P. Vertes. JAMA Psychiatry.

28. Selective brain gray matter atrophy associated with APOE ε4 and MAPT H1 in subjects with mild cognitive impairment. (2013). J Goñi, S Cervantes, G Arrondo , P Pastor , MA Pastor. J Alzheimer Dis 33(4):1009-19. Citations: 4.

27. High-Cost, High-Capacity Backbone for Global Brain Communication (2012). MP van den Heuvel, RS Kahn, J Goñi, O Sporns. Proc Natl Acad Sci USA 109(28):11372-7. Citations: 72.

26. A new kinetic framework for synaptic vesicle trafficking tested in synapsin knock-outs (2011). T Gabriel, E García-Pérez, K Mahfooz, J Goñi, R Martínez-Turrillas, I Pérez-Otaño, DC Lo, JF Wesseling. J Neurosci 31(32):11563-77. Citations: 8.

25. Modeling the effector - regulatory T cell cross-regulation reveals the intrinsic character of relapses in Multiple Sclerosis (2011) N Vélez de Mendizábal, J Carneiro, RV Solé, J Goñi, J Bragard, I Martinez-Forero, S Martinez-Pasamar, J Sepulcre, J Torrealdea, F Bagnato, J Garcia-Ojalvo, P Villoslada. BMC Syst Biol 5:114. Citations: 8.

24. Computational classifiers for predicting the short-term course of Multiple sclerosis (2011). B Bejarano, M Bianco, D Gonzalez-Moron, J Sepulcre, J Goñi, J Arcocha, O Soto, U Del Carro, G Comi, L Leocani, P Villoslada. BMC Neurol 11:67. Citations: 12.

23. Measuring the hierarchy of feedforward networks (2011) B Corominas-Murtra, C Rodríguez-Caso, J Goñi, RV Solé. Chaos 21(1) 016108. arXiv: http://arxiv.org/abs/1011.4394. Citations: 5.

22. The neural substrate and functional integration of uncertainty in decision making: an information theory approach (2011). J Goñi, M Aznárez-Sanado, G Arrondo, M Fernández-Seara, FR Loayza, FH Heukamp, MA Pastor. PLoS ONE 6(3): e17408. Citations: 10.

21. The semantic organization of the animal category: evidence from semantic verbal fluency and network theory (2011). J Goñi, G Arrondo, J Sepulcre, I Martincorena, N Vélez de Mendizabal, B Corominas-Murtra, B Bejarano, S Ardanza-Trevijano, H Peraita, DP Wall, P Villoslada. Cognitive Processing 12(2),183-196. Citations: 12.

20. Exploring the randomness of directed acyclic networks (2010). J Goñi, B Corominas-Murtra, RV Solé, C Rodríguez-Caso. Physical Review E. 82, 066115. arXiv: http://arxiv.org/abs/1006.2307. Citations: 4.

19. Topological reversibility and causality in feed-forward networks (2010). B Corominas-Murtra, C Rodríguez-Caso, J Goñi, RV Solé. New Journal of Physics 12, 113051. arXiv: http://arxiv.org/abs/1007.1829. Citations: 5.

18. Lexical access changes in patients with Multiple Sclerosis. A 2-year follow-up study (2010) J Sepulcre, H Peraita, J Goñi, B Duque, G Arrondo, I Martincorena, B Duque, N Vélez de Mendizábal, JC Masdeu, P Villoslada. J Clin Exp Neuropsyc 33(2),169. Citations: 2.

17. Switcher-random-walks: a cognitive-inspired mechanism for network exploration. (2010) J Goñi, I Martincorena, B Corominas-Murtra, G Arrondo, S Ardanza-Trevijano, P Villoslada. Int J Bifurcat Chaos 20(3):913-922. Citations: 8.

16. Brain pathways of verbal working memory: A lesion-function correlation study. (2009) J Sepulcre, JC Masdeu, MA Pastor, J Goñi, C Barbosa, B Bejarano, P Villoslada. Neuroimage 47(2):773-8. Citations: 23.

15. Morphology from Texture in Cytometry (2009) L. Peshkin, J Goñi, A Loewer, RS Kolluri, G Lahav, DP Wall, Int J of Tomography & Statistics 16, Issue No. S10 56-67. Citations: 0.

14. Allele-specific gene expression is widespread across the genome and biological processes (2009) R Palacios*, E Gazave*, J Goñi, G Piedrafita, O Fernando, A Navarro, P Villoslada. PLoS ONE 4(1): e4150. * equal contribution. Citations: 28.

13. Fractal dimension analysis of grey matter in multiple sclerosis (2009) FJ Esteban, J Sepulcre, J Ruiz de Miras, J Navas, N Vélez de Mendizábal, J Goñi, JM Quesada, B Bejarano, P Villoslada. Journal of the Neurological Sciences 282(1-2):67-71. Citations: 23.

12. Contribution of white matter lesions to gray matter atrophy in Multiple Sclerosis. Evidence from voxel-based analysis of T1 lesions in the visual pathway (2009) J Sepulcre, J Goñi, B Bejarano, N Vélez de Mendizábal, JB Toledo, JC Masdeu, P Villoslada. Archives of Neurology 66(2):173-179. Citations: 42.

11. Comparative analysis of neurological disorders focuses genome-wide search for autism genes (2008) FJ Esteban, TF DeLuca, M Huyck, T Monaghan, N Vélez de Mendizábal, J Goñi, IS Kohane, DP Wall. Genomics 93(2):120-9. Citations: 21.

10. Fatigue in multiple sclerosis is associated with the disruption of frontal and parietal pathways (2008) J Sepulcre, JC Masdeu, J Goñi, G Arrondo, N Vélez de Mendizábal, B Bejarano, P Villoslada. Multiple Sclerosis 15(3):337-44. Citations: 48.

09. Goals and pitfalls of gene network inference methods: a comparative study from virtual microarrays and network dynamics. (2008) J Goñi*, C Rodríguez-Caso*, RV Solé, P Villoslada, A Munteanu. Net-works Int Conf 2008. ISBN: 978-84-691-3819-9, pages 91-97.

08. Switcher random walkers: cognitive inspired strategies for an optimized random exploration of networks. (2008) J Goñi*, I Martincorena*, G Arrondo, J Sepulcre, N Vélez de Mendizabal, B Bejarano, DP Wall, S Ardanza-Trevijano, P Villoslada. Networks Int Conf 2008. ISBN: 978-84-691-3819-9, pags 83-89.

07. Mapping the brain pathways of declarative verbal memory. Evidence from white matter lesions in the living human brain (2008) J Sepulcre, JC Masdeu, J Sastre-Garriga, J Goñi, N Vélez de Mendizábal, B Duque, MA Pastor, B Bejarano and P Villoslada. Neuroimage 42(3):1237-43. Citations: 34.

06. A computational analysis of the protein-protein interaction networks in neurodegenerative diseases (2008) J Goñi, FJ Esteban, N Velez de Mendizabal, J Sepulcre, I Agirrezabal, S Ardanza-Trevijano, P Villoslada. BMC Systems Biology 2:52. Citations: 43.

05. HLA-DR2 and white matter lesion distribution in MS. (2008) J Sepulcre, JC Masdeu, R Palacios, J Goñi, B Moreno, M Tainta, B Bejarano, P Villoslada. (2008) Journal of Neuroimaging 18(3):328-31. Citations: 4.

04. A Network Analysis of the Human T-Cell Activation Gene Network Identifies Jagged1 as a Therapeutic Target for Autoimmune Diseases (2007) R Palacios, J Goñi, I Martínez-Forero, J Iranzo, J Sepulcre, I Melero, P Villoslada. (2007). PLoS ONE 2(11): e1222. Citations: 25.

03. Fractal dimension and white matter changes in multiple sclerosis. (2007) FJ Esteban, J Sepulcre, N Vélez de Mendizábal, J Goñi, J Navas, J Ruiz de Miras, B Bejarano, P Villoslada, NeuroImage 36(3):543-9. Citations: 33.

02. Protein interaction network analysis reveals the importance of proteins with low degree of connectivity in neurodegenerative diseases. (2006). J Goñi, FJ Esteban, N Vélez de Mendizábal, J Sepulcre, S Ardanza-Trevijano and P Villoslada. Adaptation in Artificial and Biological Systems - Network Analysis in Natural Sciences and Engineering. Proceedings of AISB06. Volume 3. ISBN 1 902956 96 7. Printed by the University of Bristol, Bristol, UK

01. Glioma-Immune Evasion: a System Dynamics Approach. (2005) J Navas, JM Quesada, J Goñi, N Vélez de Mendizábal, P Villoslada and FJ Esteban. Proceedings of II Int Conf on Computational Bioengineering. H. Rodrigues et al. Eds.

Selected Scientific Communications:

Event: 1st Neuroimaging Hackathon, IU Imaging Research Facility
Place and Date: Bloomington, IN. November 6-7, 2015
Role: J Goñi, leader of the Network Group

Event: 5th Indiana CTSI Symposium on Disease and Therapeutic Response Modeling
Place and Date: Indianapolis, IN. Nov 4-5, 2015
Title: Brain Connectomics : Challenges and Applications.
Authors: J Goñi 
Communication Type: Oral. Invited speaker

Event: Netsci'15. Brain Networks Satellite
Place and Date: Zaragoza (Spain), June 1-2 2015.
Title: Modeling resting-state functional brain networks: from population data to individual subjects
Author: J Goñi
Communication Type: Oral. Invited speaker.

Event: 4th Indiana CTSI Symposium on Disease and Therapeutic Response Modeling
Place and Date: Indianapolis, IN. Nov 12-13, 2014
Title: Network Neurodegeneration of the Human Connectome: a multiplex networks approach
Author: J Goñi
Communication Type: Oral. Invited speaker

Event: 3rd Indiana CTSI Symposium on Disease and Therapeutic Response Modeling
Place and Date: Indianapolis, IN. Nov 5-6, 2013
Title: Network Measures relating the Human Connectome to Resting-State Functional Connectivity
Author: J Goñi
Communication Type: Oral. Invited speaker

Event: AAIC 2013: Alzheimer's Association International Conference
Place and Date: Boston, MA. August. July 13-18, 2013
Title: Altered connectome mapping in Mild Cognitive Impairment and older adults with cognitive complaints.
Authors: Y Wang, J Goñi, O Sporns, SL Risacher, JD West, BC McDonald, L Shen, EF Tallman, B Ghetti, S Gao, MR. Farlow, DP. O'Neill, H Xiao, AJ. Saykin.
Communication type: Poster

Event: 2nd Indiana CTSI Symposium on Disease and Therapeutic Response Modeling
Place and Date: Indianapolis, IN. Nov 13-14, 2012
Title: Complex Systems in Neuroimaging
Author: J Goñi
Communication Type: Oral. Invited speaker

Event: Society for Neuroscience 2012
Place and Date: New Orleans, LA . Oct 13-17, 2012
Title: Predicting resting-state functional connectivity by modeling random-walk processes on structural connectivity.
Authors: J Goñi, M van den Heuvel, A Avena-Koenigsberger, R Betzel, O Sporns. Communication type: Poster

Event: 12th Granada Seminar, Physics, Computation and the Mind
Place and Date: Granada, Spain. Sept 2012
Title: Information, space and structure in the human brain resting state.
Authors: J. Goñi, A. Kolchinsky, M. van den Heuvel, A. Griffa, L. Rocha and O. Sporns.
Communication type: Oral

Event: Society for Neuroscience
Place and Date: Washington, USA, Nov 11-15th, 2011
Title: Grey matter signatures of APOE-e4 and MAPT-H1 in baseline mild cognitive impairment.
Authors: J. Goñi, S. Cervantes, G. Arrondo, P. Pastor, M.A. Pastor.
Communication type: Poster

Event: Human Brain Mapping
Place and Date: Barcelona, Spain, June 6-10th, 2010
Title: The neural substrate and functional integration of uncertainty in decision making: an information theory approach.
Authors: J. Goñi, G. Arrondo, M. Aznárez-Sanado, M. Fernández-Seara, F. Heukamp and M.A. Pastor.
Communication type: Poster

Event: Trends in Complex Systems: Synchronization and Multiscale Complex Dynamics in the Brain
Place and Date: Dresden, Germany, Nov 2-6th, 2009
Title: The role of working memory during exploratory/retrieval tasks: A graph theory perspective.
Authors: J. Goñi, B. Corominas-Murtra, G. Arrondo, M.A. Pastor and J. Bragard.
Communication type: Poster

Event: ESF workshop on Systems Biology in Medicine
Place and Date: Barcelona Spain, May 8-10th, 2008
Title: Topology, semantic modularity and search in lexical networks: evidences from verbal fluency tasks.
Authors: J. Goñi, G. Arrondo, J. Sepulcre, I. Martincorena, N. Velez de Mendizabal, B. Bejarano, S. Ardanza-Trevijano, H. Peraita, D. P. Wall, P. Villoslada.
Communication type: Poster

Event: Brain Mechanisms of Attention: Biological and Computational Approaches
Place and Date: Soria, Spain, 18-22 July 2005
Title: Sustained attention in patients with altered white matter (Multiple Sclerosis): lesion probability maps and VBM approaches.
Authors: J. Sepulcre, J. Goñi, N. Vélez de Mendizábal, P. Villoslada
Communication type: Oral

Event: Mathematics in Biology and Medicine
Place and Date: Oeiras, Portugal, September 2004
Title: A dynamic model of the innate immune response.
Authors: J.Goñi, R. García-Muñoz, N. Vélez de Mendizábal and P. Villoslada
Communication type: Oral

Referee Activity:

Conferences: MICCAI 2014, AICOM 2007, BIRD 2007-08, BIDM 2007
Journals: BMC Systems Biology, Entropy, NeuroImage, PLoS ONE, J Experimental Psychology, Brain imaging and Behavior, PLoS Computational Biology, Frontiers in Computational Neuroscience, Physical Review E.

Internships:

Group: Computational Biology Initiative, Harvard Medical School – Center for Biomedical Informatics
Director: Dennis P. Wall
Place: Boston (MA), USA
Date: April-August 2006

Group: Computational Biology Initiative, Harvard Medical School – Center for Biomedical Informatics
Director: Dennis P. Wall
Place: Boston (MA), USA
Date: January-June 2007

Group: Complex Systems Lab, Universitat Pompeu Fabra
Director: Ricard V. Solé
Place: Barcelona (Spain)
Date: May 2008 and several additional weeks during 2009 and 2010

Teaching:

2015- present      Assistant Professor at Industrial Engineering and Biomedical Engineering. Purdue University
2009-2011           Part-time Lecturer at University of Navarra in Computational and Statistical subjects
2007-2007           Teaching assistant at Systems Biology Dept. – Harvard Medical School in Bioinformatics
2006-2008           Teaching assistant at University of Navarra in Computational and Statistical subjects

Selected Courses/Meetings Attended:

2015           Structural and Functional Brain Connectivity via MRI and fMRI. Martinos Center. Boston, MA (USA). October 24-28
2014           Fourth Biennial Conference on Resting State / Brain Connectivity. Boston, MA (USA). Sept 11-13
2014           Organization for Human Brain Mapping. Hamburg (Germany). June 8-12
2014           Brain Connectivity Workshop. Hamburg (Germany). June 4-6
2013           Organization for Human Brain Mapping. Seattle (USA). June 16-20
2013           Brain Connectivity Workshop. University of British Columbia. Vancouver (Canada). June 12-14
2009           Exploring White Matter with Diffusion-Tensor Imaging. University of Bergen. Bergen (Norway)
2009           Stochastic Models in Physics, Biology, and Social Sciences. Carmona (Spain)
2005           Complex Systems: New Trends and Applications. Universidad de Cantabria. Laredo (Spain)

Grants, Awards and Other Honors:

2016-2020. NIH R01 (PI: L Shen)
Integrative Bioinformatics Approaches to Human Brain Genomics and Connectomics.
Role: Co-investigator

2016-2017 (PI: Yu-Chien Wu)
Microstructure modulated white matter connectivity for mild traumatic brain injury.
Role: Co-PI

2015-2020 NIH R01 (PI: J Harezlak)
Statistical models for multi-modal brain imaging studies of HIV-associated cognitive decline.
Role: Co-investigator

2015-2017 CTSI GLUE grant (PI: F Pestilli)
Improved accuracy for anatomical mapping and network structure of the Alzheimer’s brain.
Role: Co-investigator

2011-2016 NIH/NIA P30 AG10133 (PI: Saykin AJ)
Indiana Alzheimer Disease Center (IADC)
The major goal of this project is to support, carry out and facilitate research on Alzheimer disease and other neurodegenerative dementias as well as serving as a shared research resource.
Role: Co-investigator

2013-2015 Indiana University Imaging Research Facility seed grant.
Todd PM (PI), Goñi J, Brown J, Jones M, Hills TT.
Comparing mechanisms of memory search and spatial search in young and old adults.
Role: Co-investigator.

2014-2014 Promoted from Research Associate to Assistant Research Scientist at the Psychological and Brain Sciences Department in Indiana University.

2012-2013 Awarded with a post-doctoral research grant under the program "Estancias de movilidad postdoctoral" of the Spanish Ministry of Education. Duration: 15 months, from May 2012-July 2013.

2012 Declared accredited by the National Agency for Quality Assessment and Accreditation (ANECA) of the Spanish Ministry of Education for the contractual figures of “Profesor Contratado Doctor” (tenured, full-time), in May 2012.

2011-2014 Participation in the Brain Network Recovery Group (Brain NRG) Phase II - The Virtual Brain Project, funded by the James S. McDonnell Foundation (ref. JSMF22002082). Understanding the human brain functions and dysfunctions and create a way to simulate and predict its behaviour. http://thevirtualbrain.org/team/index.html.

2007-2010 Participation in the European Project “EU 6thFP - Complex Dis” COMPLEXDIS (ref. NEST-043241) – Unravelling Complex Diseases with Complexity Theory: from Networks to the Bedside.

2006-2008 Awarded with a predoctoral research grant under the program "Ayudas predoctorales de formacion" of the Government of Navarra. Duration: 33 months, from Jan. 2006-Sept. 2008.