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New Dual Level Course, BME 553Engineering Faculty Document No. 31-04 March 21, 2005 Page 1 of 4 TO: The Engineering Faculty FROM: The Faculty of the Department of Biomedical Engineering RE: New Dual Level Course The faculty of the Department of Biomedical Engineering has approved the following new course. This action is now submitted to the Engineering Faculty with a recommendation for approval. BME 553 Biomedical Optics Sem. 1, Class 3,
cr. 3. Prerequisite: PHYS 241 or equivalent, BIOL 295E or
equivalent Course description: Optical methods applied to address biological and biomedical problems. Course includes two parts: fundamentals of optical microscopy and advanced techniques that are currently used to probe and/or manipulate cell and tissue samples. Reasons: This course introduces biophotonics, a frontier area of biomedical engineering. A variety of advanced optical methods and their applications to biomedical research are presented. By taking this course, students will learn physical principles and practical methods of optical imaging. Students will also be able to incorporate what they learn in class to their research. This course has been taught twice on an experimental basis with an enrollment of 15 and 16 students. George Wodicka Professor and Head Engineering Faculty Document No. 31-04 March 21, 2005 Page 2 of 4 Supporting Documentation:
1. Level: Graduate and Undergraduate 2. Course
Instructor: Ji-Xin Cheng 3. Course Outline: Syllabus Class 1 Basics of light Class 2 Light matter interactions Class 3 Principle of lasers and current laser technology Class 4 Interactions of cells and tissues with light Class 5 Principles of optical microscopy Class 6 Diagnostic detection with optical spectroscopy and imaging Class 7 Labor Day Class 8 Confocal microscopy Class 9 Exam 1 Class 10 Total internal reflection fluorescence microscopy Class 11 Fluorescence energy transfer and lifetime imaging Class 12 Literature review Class 13 Two-photon fluorescence microscopy Class 14 Nonlinear optics and second harmonic generation imaging Class 15 Literature review Class 16 Single molecule fluorescence detection and spectroscopy Class 17 High-resolution imaging by near field optical microscopy Class 18 Literature review Class 19 Exam 2 Class 20 FTIR spectroscopy and imaging Class 21 Spontaneous Raman microscopy and applications to diagnostic detection Class 22 Literature review Class 23 Coherent anti-Stokes Raman scattering microscopy Class 24 Third harmonic generation microscopy Engineering Faculty Document No. 31-04 March 21, 2005 Page 3 of 4 Class 25 Literature review Class 26 Light fluctuation correlation spectroscopy Class 27 Fluorescence recovery after photo bleaching and single particle tracking Class 27 Literature review Class 28 Methods for deep tissue imaging Class 29 Literature review Class 30 Optical and magnetic tweezers Class 31 Literature review Class 32 Light fluctuation correlation spectroscopy Class 33 Literature review Class 34 Biomedical imaging with nano materials Class 35 Teraherz spectroscopy and imaging Class 36 Optical biosensors Class 37 Photodynamic therapy Class 38 Exam 3 Class 39 Course review Class 40 Student presentation of original proposals (final project) Class 41 Student presentation of original proposals (final project) Class 42 Student presentation of original proposals (final project) Class 43 Student presentation of original proposals (final project) Class 44 Student presentation of original proposals (final project) Class 45 Final exam Note for literature review: For each specific topic, two or three students will present in class a few recently published papers. Each student will submit a short paper that summarizes their comments on the significance, methods and results, strength and weakness of the papers. Textbook: Introduction to Biophotonics (John Wiley & Sons, Inc. 2003) Grading: Three exams 45% Literature review 15% Homework 20% Final project 20% Engineering Faculty Document No.31-04 March 21, 2005 Page 4 of 4 Documentation on
previous teaching Fall semester of 2003 The total number of the registered students is 15, 4 of which from BME, 8 from Chemistry, 2 from ECE, 1 from ME. The result of the student evaluation is as follows
Fall semester of 2004
The total number of the registered students is 16, 6 of which from BME, 8 from Chemistry, 2 from ME. The result of the student evaluation is as follows
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