New Grad Course, BME 658

To:             Faculty of the Schools of Engineering

From:         Department of Biomedical Engineering

Subject:      New Graduate Level Course

The Department of Biomedical Engineering has approved the following new course in BME to cross list with existing course BMS 635.  This action is now submitted to the Engineering Faculty with a recommendation for approval.

BME 658 Cell and Tissue Culture:  Techniques and Application Module (BMS 635) Sem. 2, Class 3, Lab 8, cr. 2 (5 weeks) Prerequisite:  Permission of the Instructor Required

This intensive laboratory module is designed to provide students from various disciplines (e.g., life science and engineering) with practical, hands-on experiences in the area of cell and tissue culture.  Students are taught the principles of culturing cells and tissues in vitro and have the opportunity to apply state-of-the-art culturing techniques to both 2-dimensional and 3-dimensional culture systems.  Specific methodologies focus on both qualitative and quantitative analysis of fundamental cell behavior, including proliferation, differentiation, migration, and adhesion.

Reason

This course provides students with the opportunity to learn the biophysics and engineering basis of state-of-the-art bioinstrumentation, such as flow cytometry, that is used for both qualitative and quantitative analyses of cellular and physiological systems.  At the same time students gain an understanding of and practical experience with the fundamental cellular properties (phenotype and function) and how they can be exploited for such analyses in both clinical and research settings.   This course is currently offered as BMS 635.

George R. Wodicka

Professor and Head

Supporting Documentation

Instructor:  Sherry L. Voytik-Harbin

Technical Assistant:  Beverly Waisner

Offered:  Spring

Credit:  2

Course Objectives:

            This intensive laboratory module is designed to provide students from various disciplines (e.g., life science and engineering) with practical, hands-on experiences in the area of cell and tissue culture.  Students will be taught the principles of culturing cells and tissues in vitro and will have the opportunity to apply state-of-the-art culturing techniques to both 2-dimensional and 3-dimensional culture systems.  Specific methodologies will focus on both qualitative and quantitative analysis of fundamental cell behavior, including proliferation, differentiation, migration, and adhesion.

Course Content:

Week 1:  Introduction to Cell and Tissue Culture

Week 2:  Cell Cycle and Growth Curve

Week 3:  Cell Proliferation

Week 4:  3D Cell Culture

Week 5:  Cell Differentiation