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Change in Semester offering BME 541TO: The Engineering Faculty FROM: Department of Biomedical Engineering RE: Permanent Dual Level Course Number The Department of Biomedical Engineering has approved the following course change. This action is now submitted to the Engineering Faculty with a recommendation for approval. From: BME 541 Biomedical Fluid Dynamics Sem. 2. Class 3, cr. 3. (Offered in alternate years.) Prerequisites: Senior or Graduate standing; ME309 or equivalent. Advanced principles of convective diffusion of fluids pertaining to the body, particularly vascular circulation. Topics include blood flow in arteries, convective and diffusion boundary layers in internal flows with reactive and/or permeable walls, Brownian motion, blood rheology, transport in blood, mass transport to the arterial wall, and fluid dynamics of vasculature in physiological and pathological conditions. To: BME 541 Biomedical Fluid Dynamics Sem. 1. Class 3, cr. 3. (Offered in alternate years.) Prerequisites: Senior or Graduate standing; ME309 or equivalent. Advanced principles of convective diffusion of fluids pertaining to the body, particularly vascular circulation. Topics include blood flow in arteries, convective and diffusion boundary layers in internal flows with reactive and/or permeable walls, Brownian motion, blood rheology, transport in blood, mass transport to the arterial wall, and fluid dynamics of vasculature in physiological and pathological conditions. Reason: Biomedical Engineering is beginning to offer undergraduate courses and due to the distribution of the teaching load we request a change of semester for this course offering. George R. Wodicka Professor and Head
Biomedical Fluid
Dynamics Instructor: Tom Webster Offered: fall semester (odd years) Level: Graduate level Prerequisites: Senior or Graduate standing; ME 309 or equivalent. Credits: 3 Advanced principles of convective diffusion of fluids pertaining to the body, particularly vascular circulation. Topics include blood flow in arteries, convective and diffusion boundary layers in internal flows with reactive and/or permeable walls, Brownian motion, blood rheology, transport in blood, mass transport to the arterial wall, and fluid dynamics of vasculature in physiological and pathological conditions. 3. SYLLABUS: Topics No. of Lectures Introduction to course 1 Biology of the circulatory system 4 Physical properties of the circulatory system 3 Blood flow in arteries 4 Blood rheology, constitutive equation of blood flow Blood flow in veins 3 Elastic instability, steady flow in collapsible tubes Blood flow in microcirculation 3 Pressure distribution in microvessels, mechanics of flow at low Reynolds numbers Mid-term Exam 1 Mechanics of blood cells 4 Erythrocytes, leukocytes, deformability of red blood cells Interaction of red cells with vascular walls 4 The Fahraeus – Linqvist effect Blood flow in lung 4 Pressure-flow relationship of pulmonary alveolar blood flow Examples of vascular research (group discussions) 3 Mass transport to the arterial wall Interactions between particles and conduit wall Debate 1 Flow signal transduction and vascular cell communication in arteries Blood flow in skeletal muscle 4 Resistance to flow in capillaries Student Presentations 5 Total 44 4. SUGGESTED REFERENCES AND/OR TEXTBOOKS: 1. Batchelor
GK: An Introduction to Fluid Dynamics. 2. Happel J and Brenner H: Low Reynolds Number
Hydrodynamics. Martinus Nijhoff Publishers, 3. Fung YC: Biomechanics: Circulation. 4. Fung
YC: Biomechanics: Motion, Flow, Stress, and Growth. 5. Fung
YC: Biomechanics: Mechanical Properties of Living Tissues. 6. Guyton AC and Hall JE: Textbook of Medical
Physiology. W.B. Saunders Company, 5. PREVIOUS EVALUATIONS
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