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Permanent Course: BME 541 Biomedical Fluid DynamicsTO: The Engineering Faculty FROM: Department of Biomedical Engineering RE: Permanent Dual Level Course Number The Department of Biomedical Engineering has approved the following new course. This action is now submitted to the Engineering Faculty with a recommendation for approval. BME 541 Biomedical Fluid Dynamics A.
Course Description Sem. 2. Class 3, cr. 3. (Offered in alternate years.) Prerequisites:
Senior or Graduate standing; must have taken at least one undergraduate course in fluid dynamics. Course description: Course discusses advanced principles of convective diffusion of fluids pertaining to the body, particularly vascular circulation. Topics include: blood flow in arteries, convective and diffusion boundary layers in internal flows with reactive and/or permeable walls, Brownian motion, blood rheology, transport in blood, mass transport to the arterial wall, and fluid dynamics of vasculature in physiological and pathological conditions. Reason: The second time this course was taught was in the Fall of 2002. No courses currently exist at Purdue that specifically addresses Biomedical Fluid Dynamics. George R. Wodicka Professor and Head
1. COURSE TITLE: Biomedical Fluid Dynamics 2. COURSE DESCRIPTION: Offered: fall
semester (odd years) Level: Graduate level Prerequisites: Graduate standing or permission of the instructor required Credits: 3 Course discusses advanced principles of convective diffusion of fluids pertaining to the body, particularly vascular circulation. Topics include: blood flow in arteries, convective and diffusion boundary layers in internal flows with reactive and/or permeable walls, Brownian motion, blood rheology, transport in blood, mass transport to the arterial wall, and fluid dynamics of vasculature in physiological and pathological conditions. 3. SYLLABUS: Topics No.
of Lectures Introduction to course 1 Biology of the circulatory system 4 Physical properties of the circulatory system 3 Blood flow in arteries 4 Blood rheology, constitutive equation of blood Blood flow in veins 3 Elastic instability, steady flow in collapsible tubes Blood flow in microcirculation 3 Pressure distribution in microvessels, mechanics of flow at low Reynolds numbers Mid-term Exam 1 Mechanics of blood cells 4 Erythrocytes, leukocytes, deformability of red blood cells Interaction of red cells with vascular walls 4 The Fahraeus – Linqvist effect Blood flow in lung 4 Pressure-flow relationship of pulmonary alveolar blood flow Examples of vascular research (group discussions) 3 Mass transport to the arterial wall Interactions between particles and conduit wall Debate 1 Flow signal transduction and vascular cell communication in arteries Blood flow in skeletal muscle 4 Resistance to flow in capillaries Student Presentations 4 Final Exam 1 Total 44 4. SUGGESTED REFERENCES AND/OR TEXTBOOKS: 1. Batchelor
GK: An Introduction to Fluid Dynamics. 2. Happel J and
Brenner H: Low Reynolds Number Hydrodynamics. Martinus Nijhoff
Publishers, 3. Fung YC:
Biomechanics: Circulation. 4. Fung YC: Biomechanics: Motion, Flow, Stress, and Growth. 5. Fung YC: Biomechanics: Mechanical Properties of Living
Tissues. 6. Guyton AC and Hall
JE: Textbook of Medical Physiology. W.B. Saunders Company, 5. PREVIOUS EVALUATIONS
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