Permanent Course: BME 583 Biomaterials

 

 

TO:         The Engineering Faculty

FROM:   Department of Biomedical Engineering

RE:          Permanent Dual Level Course Number

 

            The Department of Biomedical Engineering has approved the following new course.  This action is now submitted to the Engineering Faculty with a recommendation for approval. 

 

BME 583  Biomaterials 

 

A.           Course Description

 

         Sem. 2. Class 3, cr. 3. (Offered in alternate years.)

 

Prerequisites:

Permission of the instructor required

 

 

Course description:

Course discusses principles of biomaterial design, synthesis, and evaluation for various tissues/organs of the body including orthopaedic/dental, cardiovascular, kidney, liver, lung, skin, nerve, and brain.  Topics include fundamentals of materials science and engineering integrated into biology for the better regeneration of tissue.

 

Reason:

The third time this course was taught was in the Fall of 2003. No courses currently exist at Purdue that specifically addresses Biomaterials Science and Engineering.

 

 

 

 

 

George R. Wodicka

Professor and Head

                                                           

                                                           

                                                           

 

 

Supporting Documentation:

 

Course Instructor:  Tom Webster

Offered:  fall semester (even years)

 

 

Course Objective:

To integrate materials science and engineering concepts with biology to educate students how to design successful biomaterials.

 

 

3. SYLLABUS:

 

                        Topics                                                              No. of Lectures

 

            Introduction to course                                                   1         

            Structure of solids                                                         3

                        Atomic bonding, crystal structure, imperfections

            Characterization of materials                                         4

                        Mechanical properties, stress-strain behavior

                        Viscoelasticity, thermal properties, phase diagrams

                        Strengthening mechanisms, surface properties                           

                        Metallic implant materials                                              3

            Ceramic implant materials                                             3

            Polymeric implant materials                                           4

                        Composites as biomaterials                                           2

                        Structure-property relationships in biology                     3

Proteins, polysaccharides, mineralized tissue: bone/dentin

                        Organ Transplants                                                        3

                        Tissue response to biomaterials                         7

Normal wound healing process, body response to implants

Cell response to biomaterials                                         8

                        Protein mediated cell adhesion                         

Student Presentations                                                    3

           

                                                                                    Total                44

 

4. SUGGESTED REFERENCE AND/OR TEXTBOOKS:

 

1.      Park JB and Lakes RS: Biomaterials an Introduction. Plenum Press, New York, 1992.

2.   Ratner BD, Hoffman AS, Schoen FJ, Lemons JE: Biomaterials Science: An Introduction to Materials in Medicine. Academic Press, New York, 1996.

3.   Hudson JB: Surface Science. Butterworth-Heinemann, Boston, 1992.

4.   Simon SR: Orthopaedic Basic Science. American Academy of Orthopaedic Surgeons, Rosemont, IL, 1994.    

5.      Fung YC: Biomechanics: Mechanical Properties of Living Tissues. Springer-Verlag, New York, 1993.

6.   Guyton  AC and Hall JE: Textbook of Medical Physiology. W.B. Saunders Company, Philadelphia, 1996.

 

 

5. DOCUMENTATION ON PREVIOUS COURSE OFFERINGS: