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New Course: BME 306. Biotransport LaboratoryEngineering Faculty Document No. 24-03 Page 1 of 3 TO: The Engineering Faculty FROM: The Faculty of the Department of Biomedical Engineering RE: New Undergraduate-Level Course The faculty of the Department of Biomedical Engineering has approved the following new course. This action is now submitted to the Engineering Faculty with a recommendation for approval. BME 306 Biotransport Laboratory Sem. 2. Lab 3, cr. 1. Prerequisite: ME 309 or equivalent Corequisite: BME
304 Practical experience with fluid, mass,
and heat transport principles and dimensional analysis relevant to biomedical
applications. Experiments include
simulations of normal and pathological
conditions of blood flow with vessel constructs, mass transfer in unique
boundary layers and molecular
diffusion in cell and tissues, heat generation and transfer in biomaterials emphasizing tissue-tissue and tissue-cell
interfaces. Reason: Providing students with practical experience with the transport phenomena (mass, heat, and fluid) of physiological processes is important for reinforcing fundamental engineering principles within a biomedical context. George Wodicka Professor and Head Engineering Faculty Document No. 24-03 Page 2 of 3 Supporting Documentation:
1. Level: Undergraduate – junior year 2. Course
Instructor: Thomas J. Webster 3. Course Outline: Fluid Transport (8 labs): Lab 1: Low (capillary blood flow) and high (arterial blood
flow) Reynolds number flow demonstration under normal and pathological
conditions Lab 2: Effect of wave propagation effects on fluid motion
in the body (specifically, heart
pumping frequency on blood, and eating/drinking frequency on food/fluid
movement in digestive tract) Lab 3: Use of dimensional analysis in laboratory
(experimental) models for simulating in vivo capillary blood flow Lab 4: Turbulent blood flow
conditions on physiological and pathological responses of cells that line the
vasculature (endothelial cells) Lab 5: Development of arterioscelerosis due to flow separation at boundary layer
flow in arteries. Lab 6: Inviscid, incompressible blood flow
around red blood cells in arteries, veins, and capillaries Lab 7: Fluid mechanics of air flow
in physiological and pathological conditions of the lung Lab 8: Roughness effects on blood flow across vessel
constructs Mass Transport (4 labs): Lab 9: Importance of mass transfer
in unique boundary layers – biofilm and the
foreign-body response layers Lab 10: Mass
transfer in the body independent of chemical reactions (lungs) Lab 11: Mass
transfer in the body dependent on chemical reactions (Na+ and K+
exchange) Lab 12: Unsteady-state
molecular diffusion such as in drug delivery mechanisms and effects on cell and
tissues Heat Transport (3 labs): Lab 13: Heat generation and its
effects through use of biomaterials (specifically, PMMA for bone prostheses,
etc.) Lab 14: Unsteady-state generation of heat during
pathological conditions (such as fever conditions) Lab 15: Heat transfer in arteriosclerosis (turbulent flow)
conditions emphasizing tissue-tissue and tissue-cell interfaces Week 16: Finals
week – no laboratory Engineering
Faculty Document No. 24-03 Page 3 of 3 4. Text: laboratory
manual to be prepared by the instructors and technical staff. 5. Grading: based on pre-laboratory assignments and weekly laboratory reports. |
