New Course: BME 202. Biomaterials

Engineering Faculty Document No. 15-03

September18, 2003

Page 1 of 3

TO: The Engineering Faculty

FROM: The Faculty of the Department of Biomedical Engineering

RE: New Undergraduate-Level Course

The faculty of the Department of Biomedical Engineering has approved the following new course. This action is now submitted to the Engineering Faculty with a recommendation for approval.

BME 202 Biomaterials

 

Sem. 2. Class 3, cr. 3.

 

Prerequisite: BME 205, ME 270

Corequisite: BME 206, BME 204

 

 

Covers the fundamentals of materials science and engineering concepts in a biological application context. Crystal structure, deformation of materials, characterization of materials, and performance of materials as implants. Integrated biological topics include bone physiology/anatomy, cells of bone, cell structure, and protein-mediated cell attachment. Emphasizes the unique biological criteria which must be considered when designing synthetic materials for implants.

 

 

Reason: Introducing students to the wide range of materials and properties which can be used to interact with physiological systems in a biomedical engineering context is important to understand and to develop implantable medical devices.

 

 

George Wodicka

Professor and Head

Engineering Faculty Document No. 15-03

September 18, 2003

Page 2 of 3

Supporting Documentation:

1. Level: Undergraduate – sophomore year

2. Course Instructor: Thomas J. Webster

3. Course Outline:

Topics in order Lectures

Structure (10 lectures):

– Atomic bonding (1 lecture) / Crystal structure (2 lectures) 3

– Atoms of the same size / different size (1 lecture each) 2

– Imperfections in crystalline structures 3

– Definition of metals / ceramics / long-chain molecular

compounds / polymers / Composite material structure 2

 

Processing (6 lectures):

– Forging, rolling, extrusion, drawing, cold-working /

Strengthening grain boundaries 3

– Strain aging / Fiber and Martensite strengthening / Annealing

and sintering / Strengthening of polymers and elastomers 3

 

Characterization (16 lectures):

– Stress-strain behavior / Mechanical failure / Tension,

compression, and bending tests 3

– Hardness, Torsion, Fracture toughness, and Fatigue testing 2

– Viscoelasticity 2

– Phase diagrams, Surface and Thermal Properties 3

– Electrical and Optical properties, X-ray absorption 3

– Density, Porosity, Acoustic and ultrasonic properties,

and Diffusion 3

 

Biological Applications (9 lectures):

– Bone biology/physiology, Tissue response to implants 3

– Tissue response to implants (cont.), Metallic and Ceramic

implant materials 3

– Polymeric implant materials, Biological (natural) and

Composite materials 3

 

EXAMS 3

Total 44

 

Engineering Faculty Document No. 15-03

September18, 2003

Page 3 of 3

 

 

4. Text:

 

Ratner BD, Hoffman AS, Schoen FJ, Lemons JE: Biomaterials Science:

An Introduction to Materials in Medicine. Academic Press, New York, 1996.

 

 

5. Grading: based on exams, homework, quizzes, and computational assignments.