Joseph Wallace Teaching Responsibilites
Professor Wallace joined the Department of Biomedical Engineering at IUPUI in the Fall semester of 2010. Since that time, he has taught undergraduate and graduate courses in the cirriculum associated with general mechanical principles applied to biomedical applications, and more specific course in bone mechanics and mechanobiology. Below is a list of courses taught with general information about each.BME 24101 and BME 24300: Introductory Biomechanics Lecture and Lab (note: this was a single course, BME24100, prior to Fall 2019), Courses taught each Fall semester.:
The lecture portion of this course uses didactic lecture material to introduce students to the principles of mechanics and how these concepts apply to musculoskeletal tissues. General course topics for BME 24101 include:
- Newton’s Laws
- Forces and moments
- Analysis of systems at equilibrium and free body diagrams
- Analysis of structures
- Concepts of stress: axial loading, torsional loading, bending, and combined loading
- Introduction to skeletal tissues
BME 24300 uses laboratory experiments to introduce students to the principles of mechanics and how these concepts apply to musculoskeletal tissues. Students will also explore ethical issues associated with animal use in biomedical research. Experiments include:
- Calculating three dimensional force vectors using a force plate
- Harvesting and storing biological tissues for mechanical characterization
- Applying single element strain gauges and measuring strain
- Mechanical testing of engineering and biological materials in tension, compression, and bending
- Basic finite element modeling and design
- Ethical considerations in animal-based biomedical research
BME 54400: Musculoskeletal Biology and Mechanics (Course taught every other Spring semester):
This course covers topics relevant to skeletal tissues (bone, tendon, ligament, cartilage and meniscus) including skeletal morphology, physiology, cell biology, development, adult osteogenesis, tissue mechanics, mechanical adaptation, failure (fracture), and fracture fixation. General topics include:
- Tensors, small strains and linear elasticity
- General musculoskeletal anatomy and important molecules of connective tissues
- Bone morphology, physiology, and hierarchical organization
- Bone cells, embryonic skeletal development (IO and EO), growth, modeling, remodeling, histomorphometry
- General bone mechanics and mechanical testing; Characterizing bone material properties
- Bone fracture toughness
- Bone adaptation to mechanical environment, general mechanotransduction
- Bone fatigue and damage, fracture, fracture healing, mechanical stabilization; Implant mechanics
- Large deformation theory
- Mechanical properties of tendons and ligaments
- Synovial joint mechanics (cartilage, meniscus, the growth plate)
BME 59500: Engineering Analysis of Tissues (Course taught every other Spring semester):
This course will cover the principles of a number of characterization methods used to assess the quantity and quality of tissues. The course will primarily focus on musculoskeletal tissues, although techniques are relevant to other tissues as well. General topics include:
- Large scale mechanical testing
- Fracture toughness testing and fatigue
- DMA, viscoelasticity
- X ray, microCT, pQCT, Synchrotron, DEXA
- SAXS/WAXS/XRD
- TEM/SEM/qBSEM
- Raman/FTIR
- Polarized light and SHG – tissue organization
- Contact based indentation (Nanoindentation, Biodent)
- AFM-based imaging and mechanical testing (indentation, bending, pulling, friction)
- Histology and histomorphometry
- In vitro cell techniques (culturing, qPCR, etc.)
- In vitro and in vivo mechanical loading (techniques, strain gage theory)