Other Personnel: Manager / Postdocs / Grad Students / Undergrads

Joseph M Wallace, Ph.D.

Joseph Wallace Associate Vice President for Research Development for Indianapolis (July 2024 - Current)
Purdue University

Professor and Indianapolis Site Director (July 2024 - Current)
Weldon School of Biomedical Engineering
Purdue University

Professor (adjunct, 2013 - Current)
Department of Orthopaedic Surgery
Indiana University School of Medicine

jwalla78@purdue.edu
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Overall Research Interests:
Professional Experience:
July 2024 - Associate Vice President for Research Development for Indianapolis, Purdue University
July 2024 - Professor and Indianapolis Site Director, Weldon School of Biomedical Engineering, Purdue University
2013 - Department of Orthopaedic Surgery, Indiana University School of Medicine
Professor (Adjunct, 2020-)
Associate Professor (Adjunct, 2016-2020)
Assistant Professor (Adjunct, 2013-2016)
July 2023 - July 2024 Acting Dean, Purdue School of Engineering and Technology, IUPUI
Jan 2020 - July 2024 Chair, Department of Biomedical Engineering, IUPUI
2010 - 2024 Department of Biomedical Engineering, IUPUI
Professor (2020-2024)
Associate Professor (2016-2020)
Assistant Professor (2010-2016)
Graduate Program Faculty, Weldon School of Biomedical Engineering, Purdue University
2007 - 2010 Postdoctoral Fellow, Department of Chemistry, University of Michigan
Michigan Nanotechnology Institute for Medicine and Biological Sciences
2004 - 2007 Ph.D., Department of Biomedical Engineering, University of Michigan
2002 - 2004 M.S., Department of Biomedical Engineering, University of Michigan
1997 - 2002 B.S., Department of Aerospace Engineering, Georgia Institute of Technology
Recent Honors and Awards:
2021 Fellow, American Society for Bone and Mineral Research (ASBMR)
2021 Abraham M. Max Distinguished Professor Award
2019 VA Intramural Non-Clinician Scientist Program
2019 Kathryn J. Wilson Award for Outstanding Leadership and Mentoring of Undergraduate Research
2019 IUPUI Digital Faculty Fellow, Inaugural Class
2018 IUPUI Trustees' Teaching Award
2015 Featured investigator in the 2014 IUPUI Research Report
Current Research Support:
NIH/NIDDK, R01 DK134101 (multi-PI; 1.5 academic months)
Uremic toxins and osteocyte dysfunction in CKD
12/01/2023 – 11/30/2027

NIH/NIAMS, R01 AR080118 (multi-PI; 1.35 academic months)
How Bisphosphonates Affect Bone Matrix and Remodeling: Implications for Atypical Femoral Fractures
05/12/2023 – 03/31/2028

VA Merit Award, I01 BX005990 (PI; 5/8th VA Appointment)
Improving bone mass and quality in comorbid diabetes and chronic kidney disease
01/01/2023 – 12/31/2026

NIH/NIAMS, R01 AR078914 (Co-I; 0.6 academic months)
Mechanisms of Bone Fragility in Autosomal Dominant Osteopetrosis Type II
09/01/2022 – 05/31/2027

NIH/NIDDK, R01 DK134101 (Co-I; 0.6 academic months)
Precision medicine approaches to renal osteodystrophy
09/01/2022 – 06/30/2027

NIH/NIAMS, R01 AR080076 (Co-I; 0.7 academic months)
Uncovering the dual anabolic and anti-catabolic effects of Pyk2 inhibition on bone mass
08/22/2022 – 07/31/2027

VA Merit Award, I01 BX005154 (Co-I; 0.50 academic months)
Skeletal complications to a TREM2 variant associated with Alzheimer's Disease
07/01/2021 – 06/30/2025

VA Merit Award, I01 BX003025 (Co-I; 1.2 academic months)
Treating bone deterioration associated with chronic kidney disease
01/01/2021 – 12/31/2024

NSF, 1952993 (multi-PI; 1.0 summer months)
LEAP-HI: Engineering New Solutions to Reduce the Burden of Skeletal Fracture
06/01/2020 – 05/31/2026 (NCE)

Pending:
NIH/NIAMS, R01 AR072609 Renewal (PI; 1 academic, 1 summer month); Submitted March 2023 (Scored at 45%, resubmission expected Feb 2024)
Targeting collagen as an interventional approach to improve bone material properties
12/01/2023 – 11/30/2028

NIH/NIAMS, R01 ARXXXXXX (Co-I; 0.45 academic months); Submitted Mar 2024
Modifiers of Down Syndrome Co-occurring Phenotypes
04/01/2025 – 03/31/2030

Completed Research Support:
NIH/NIDDK, F30 DK121399 (Mentor; 0.0 academic months)
The Effect of Etelcalcetide on Bone-tissue Properties in End Stage Kidney Disease
06/01/2019 – 05/31/2024

NIH/NIAMS, R01 AR072609 (PI; 1 academic, 2 summer months)
Targeting collagen as an interventional approach to improve bone material properties
07/05/2018 – 05/31/2024 (NCE)

NIH/NIAMS, R21 AG078861 (Co-I; 0.45 academic months)
Contribution of chromosome versus gonadal sex to bone mass and strength
07/15/2022 – 03/31/2024

NIH/NIAMS, R01 AR073739 (Co-I; 1.35 academic months)
The Nmp4 Anti-Anabolic Bone Axis
08/15/2018 – 07/31/2023

IUPUI Office of Academic Affairs Department Enhancement Grant (multi-PI; 0.0 academic months)
Building Toward the Recruitment, Retention and Advancement of a Diverse Biomedical Engineering Faculty at IUPUI
11/01/2020 - 10/31/2022

Indiana Center for Musculoskeletal Health Pilot Grant (multi-PI; 0.0 academic months)
Regulation of osteocyte connectivity and bone health by Kalirin
10/01/2021 - 09/30/2022

Indiana CTSI Grant Linking University-wide Expertise (GLUE) (multi-PI; 0.0 academic months)
Studies of Raloxifene Analogs for Improved Properties of Bone Health
05/01/2019 – 04/30/2022 (NCE)

IUPUI Office of the Vice Chancellor for Research, Research Support Funds Grant (PI; 0.0 academic months)
Developing a Combined Model of Diabetes and Chronic Kidney Disease
06/01/2019 – 05/30/2021 (NCE)

Ralph W. and Grace M. Showalter Research Trust Fund (Co-I; 0.0 academic months)
Mechanisms underlying tendon dysfunction associated with diabetes
07/01/2019 – 06/30/2021 (NCE)

NIH/NICHD, R15 HD090603 (Co-I; 0.0 academic months)
Development and Treatment of Skeletal Deficits in a Down Syndrome Mouse Model
07/01/2017 – 06/30/2020

NIH/NIDDK, R01 DK110871 (Co-I; 0.45 academic months, years 3-4)
Pathogenesis of compromised bone quality and mechanics in chronic kidney disease
07/01/2016 – 06/30/2020

VA Merit Award, I01 BX003025 (Co-I; 1.2 academic months, years 3-4)
Treating bone deterioration associated with chronic kidney disease
07/01/2016 – 06/30/2020

IUPUI Biomechanics and Biomaterials Research Center Pilot Grant (PI; 0.0 academic months)
Enhancing collagen hydration as a novel way to improve bone mechanics
09/01/2017 – 8/30/2018

NIH/NIAMS, K25 AR067221 (PI; 7 academic, 2 summer months)
Mechanical Protection of Pathological Collagen Synthesis
07/01/2015 – 06/30/2018

NSF EAGER 1643116 (Co-I; 0.0 academic months)
EAGER: Mechanical size effects and bone failure
07/01/2016 – 06/30/2018

Indiana CTSI Core Facility Pilot Proposal (PI; 0.0 academic months)
Second Harmonic Generation Imaging of Collagen Structure in Bone
09/01/2015 – 08/31/2016

Ralph W. and Grace M. Showalter Research Trust Fund (Co-I; 0.0 academic months)
Enhancing skeletal mechanical properties in Osteogenesis Imperfecta
07/01/2015 – 06/30/2016

NIH/NHLBI, R01 HL126705 (Collaborator, 0.9 academic months)
Analysis of TGFbeta Ligands Function in Heart Development and Disease
04/01/2015 – 01/01/2016

Indiana CTSI Research Invention and Scientific Commercialization (RISC) grant (Co-I; 0.0 academic months)
Novel Pharmacological Treatment of Osteogenesis Imperfecta
09/01/2014 – 08/30/2015

IUPUI Office of the Vice Chancellor for Research, Research Support Funds Grant (Co-I; 0.0 academic months)
High-Performance Liquid Chromatography Fluorescence Detector for Biological Assays
06/2014 - 05/2015

IUPUI Biomechanics and Biomaterials Research Center Pilot Grant (Co-PI; 0.0 academic months)
Enhancing bone mechanical properties in osteogenesis imperfecta through combination drug treatment
02/01/2014 – 01/31/2015

IUPUI Biomechanics and Biomaterials Research Center Pilot Grant (Co-I; 0.0 academic months)
Biomechanical effects of low-intensity, multi-directional loading on bone and muscle growth
01/01/2014 – 12/31/2014

IUPUI Office of the Vice Chancellor for Research, Research Support Funds Grant (PI; 0.0 academic months)
Effects of in vivo and ex vivo tibial compression on bone damage accrual and fracture toughness in normal and osteolathyritic mice
01/01/2014 – 12/31/2014

IUPUI Biomechanics and Biomaterials Research Center Pilot Grant (PI; 0.0 academic months)
Mechanical Stimulation, Fracture Resistance and Fracture Healing in Bone
01/01/2014 – 12/31/2014

IUPUI Office of the Vice Chancellor for Research, Research Support Funds Grant (PI; 0.0 academic months)
Nanoscale Structure/Function Relationships in Osteogenesis Imperfecta
07/01/2011 – 06/30/2012

NIH/NIDCR, F32 DE018840 (PI; 12 calendar months)
Investigating Ultrastructural Collagen Changes in Osteogenesis Imperfecta
08/01/2008 – 07/31/2010


Current Professional Memberships:
  • Orthopaedic Research Society (ORS) 2008-current:
  • The American Society for Bone and Mineral Research (ASBMR) 2009-current:
  • Biomedical Engineering Society (BMES) 2009-2015, 2020-current
  • American Society of Mechanical Engineers (ASME) 2021-current



    • Journal Editorial Boards:

    Ad Hoc Journal Reviewer:
    Acta Biomaterialia, ACS Applied Materials & Interfaces, Advances in Manufacturing, Biomedicine and Pharmacotherapy, Bone, Bone Reports, Calcified Tissue International and Musculoskeletal Research, Cell and Tissue Banking, Clinical Reviews in Bone and Mineral Metabolism, Connective Tissue Research, Heliyon, Journal of American Aging Association, Journal of Biomechanical Engineering, Journal of Biomechanics, Journal of Biophotonics, Journal of Bone and Mineral Metabolism, Journal of Bone and Mineral Research, Journal of Dental Research, Journal of Mechanical Behavior of Biological Materials, Journal of Orthopaedic Research, Materials Research Society, Matrix Biology, Micron, Nature, Osteoporosis International, Pediatric Research, Plos One, Proceedings of the National Academy of Sciences, Scanning, Scientific Reports, Stem Cell Research & Therapy, Tissue Engineering, Ultrasonics – Sonochemistry


    Teaching: Note: for more details on these courses, please see my Teaching page.

    How to connect with the BBML: