Pharma LPRC - Immunoengineering Inmmunotherapies: Immunoengineering for next-generation immunotherapies
This project aims to advance next-generation immunotherapies for difficult-to-treat diseases, including cancer and neurological disorders, by combining immunoengineering with advanced manipulation of the immune system for therapeutic use. Through the design and analysis of cellular and tissue systems and models, including immune cells and their interactions with tissues and diseases, the research seeks to deepen understanding of immune function and enhance therapeutic efficacy. In parallel, the project develops physiologically relevant organoid systems, including brain-like tissues, to study interactions between engineered immune cells and complex disease microenvironments. Together, these complementary approaches provide a robust framework for uncovering disease mechanisms, optimizing immune-based strategies, and accelerating the translation of innovative therapies.
Faculty Mentor:
Description:
This project aims to advance next-generation immunotherapies for difficult-to-treat diseases, including cancer and neurological disorders, by combining immunoengineering with advanced manipulation of the immune system for therapeutic use. Through the design and analysis of cellular and tissue systems and models, including immune cells and their interactions with tissues and diseases, the research seeks to deepen understanding of immune function and enhance therapeutic efficacy. In parallel, the project develops physiologically relevant organoid systems, including brain-like tissues, to study interactions between engineered immune cells and complex disease microenvironments. Together, these complementary approaches provide a robust framework for uncovering disease mechanisms, optimizing immune-based strategies, and accelerating the translation of innovative therapies.
The student will participate in the experimental components of the project and conduct studies across one or more areas, including the evaluation of immune-engineering strategies to improve immune cell function, the development and assembly of organoid systems, and the functional and analytical assessment of molecular, engineering, and therapeutic aspects of immune–disease interactions. In addition to data collection, the student will analyze and visualize data and present their research findings.
Prerequisites:
No required prerequisites but understanding of biology, biochemistry, genetics, immunology is a plus.