LPRC Microfluidic System: Microfluidic system for studying the transport of therapeutics.
This student team will focus on cutting-edge pharmaceutical research in the discovery/development areas, aiming to advance global healthcare and to benefit patients worldwide. The team will have access to advanced research technologies and will develop tools and protocols to address critical research inquiries
Faculty Advisor:
Description:
The development of a microfluidic model for various therapeutics, ranging from various sizes and concentrations, will be explored. Transport within the hydrogels will be analyzed to generate correlations with the various aspects of the therapeutic solutions. Microfluidic models have been recognized as an interesting alternative to animal models for drug screening. These models can mimic some of the physiological characteristics across solid tumors to the physiological barriers. The therapeutic solution will be injected into one of the microchannels, while the other microchannel wells will have the hydrogel formulations in them. The transport of the therapeutic solution in the hydrogel will be measured by fluorescence microscopy or other techniques.
Prerequisites:
Biomaterial synthesis and fluorescence microscopy techniques are a plus, but not a requirement.