LPRC Fluidic Device: Fluidic device for studying the transport of therapeutics during pregnancy
This student team will focus on cutting-edge pharmaceutical research in the discovery/development areas, aiming to advance global healthcare and to benefit patients worldwide. The team will have access to advanced research technologies and will develop tools and protocols to address critical research inquiries. Student teams will be formed based on interests and expertise to work on the following projects.
Faculty Advisors:
Professor Arezoo M. Ardekani and Professor Ryan Wagner
Description:
Fluidic devices that mimic selected physiological conditions can be used to better understand the transport physics of therapeutics. Pregnant women are often excluded from clinical trials leading to a lack of data on the performance of drugs during pregnancy. To help address this gap we will develop, characterize, and test fluidic devices that mimic aspects of the transport phenomena linking the mother and fetus at different stages of pregnancy. Transport of therapeutics within the device will be measured with fluorescence microscopy. Mechanical testing will be used to understand the deformation of the device in response to expected forces. If successful, we will improve the access to and understanding of therapeutic treatments for pregnant women.
Prerequisites:
N/A