Research | LIMR

RESEARCH

Actuators

Magnetic microactuator enabled self-clearing catheters

Yang, Q., Park, H., Nguyen, T. N. H., Rhoads, J. F., Lee, A., Bentley, R. T., Judy, J. W., and Lee, H. Anti-biofouling implantable catheter using thin-film magnetic microactuators. Sensors and Actuators B: Chemical, 273, pp. 1694-1704, 2018.

Yang, Q., Lee, A., Bentley, R. T., and Lee, H. Piezoeresistor-embedded multifunctional magnetic microactuators for implantable self-clearing catheter. IEEE Sensors Journal, 19, 4, pp. 1373-1378, 2019.

Smart glaucoma drainage devices

Park, H., Raffiee, A. H., John, S. W. M., Ardekani, A. M., and Lee, H. Towards smart self-clearing glaucoma drainage device. Microsytems and Nanoengineering, 4, 35, 2018.

Automatic antidote delivery system for treatment of opioid overdose

Dhowan, B., Lim, J., MacLean, M. D., Berman, A. G., Kim, M. K,, Yang, Q., Linnes, J., Lee, C. H., Goergen, C. J., Lee, H. Simple minimally-invasive automatic antidote delivery device (A2D2) towards closed-loop reversal of opioid overdose. Journal of Controlled Release, 306, pp. 130-137, 2019.

Magnetic actuator-enabled 3D cell culture system for cancer research

Enríquez, Á, Libring, A., Field, T. C., Jimenez, J., Lee, T., Park, H., Satoski, D., Wendt, M. K., Calve, S., Tepole, A. B., Solorio, L., and Lee, H., High‐Throughput Magnetic Actuation Platform for Evaluating the Effect of Mechanical Force on 3D Tumor Microenvironment, Advanced Functional Materials, 2005021, 2020.

Sensors

Printable implantable glutamate biosensor using conductive Pt nanoparticle composite ink

Nguyen, T. N. H., Nolan, J. K., Park, H., Lam, S., Fattah, M., Joe, H-E, Lee, H., Kim, S. J., Jun, M. B. G., Shi, R., and Lee, H. Facile fabrication of glutamate biosensor using direct writing of platinum nanoparticle-based nanocomposite ink. Biosensors and Bioelectronics, 135, 15, pp. 257-266, 2019.

Activated carbon-Pt based printable glutamate biosensor

Nguyen, T. N. H., Nolan, J. K., Cheng, X., Park, H., Wang, Y., Lam, S., Lee, H., Kim, S. J., Shi, R., Chubykin, A. A. and Lee, H., Fabrication and ex vivo evaluation of activated carbon-Pt microparticle based glutamate biosensor. Journal of Electroanalytical Chemistry, 114136, 2020.

Multi-analyate biosensor array

Nolan, J.K., Nguyen, T.N., Le, K.V.H., DeLong, L.E. and Lee, H., Simple Fabrication of Flexible Biosensor Arrays Using Direct Writing for Multianalyte Measurement from Human Astrocytes. SLAS TECHNOLOGY: Translating Life Sciences Innovation, p.2472630319888442, 2019.

CNT-PtNP based non-enzymatic glucose biosensor and the non-linear modeling

Nguyen, T. N. H., Jin, X., Nolan, J. K., Xu, J., Le, K. V. H., Lam, S., Wang, Y., Alam, M. A., Lee, H. Printable Nonenzymatic Glucose Biosensors Using Carbon Nanotube-PtNP Nanocomposites Modified with AuRu for Improved Selectivity, ACS Biomaterials Science & Engineering, 6, 9, 5315–5325, 2020.

Perovskite-based implantable glutamate biosensor for in vivo cortical monitoring

Nguyen, T. N. H., Nolan, J. K., Park, H., Lam, S., Fattah, M., Joe, H-E, Lee, H., Kim, S. J., Jun, M. B. G., Shi, R., and Lee, H. Facile fabrication of glutamate biosensor using direct writing of platinum nanoparticle-based nanocomposite ink. Biosensors and Bioelectronics, 135, 15, pp. 257-266, 2019.

Anti-biofouling strategies

Simple fabrication technique to create a large-scale, anti-inflammatory biomimetic nanotexture

Xu, J., Moon, H., Xu, J., Lim, J., Fischer, T., Mcnally, H. A., Sintim, S. O., and Lee, H. One-step Large-scale Nanotexturing of Non-planar PTFE Surfaces to Induce Bactericidal and Anti-inflammatory Properties, ACS Applied Materials and Interfaces, 26893–26904, 2020.

Novel conductive material towards fabrication of anti-biofouling implantable sensors and actuators

Xu, J., Xu, J., Moon, H., Sintim, H.O. and Lee, H., Zwitterionic Porous Conjugated Polymers as a Versatile Platform for Antibiofouling Implantable Bioelectronics. ACS Applied Polymer Materials, 9b00950, 2020.

Xu, J., Xu. J., Moon, H., Sintim, H. O., and Lee, H., Zwitterionic liquid crystalline polythiophene as an antibiofouling biomaterial, Journal of Materials Chemistry B, 2021.

Xu, J., and Lee, H. Anti-Biofouling Strategies for Long-Term Continuous Use of Implantable Biosensors, Chemosensors, 8(3), 66, 2020.

Neural interface

Development of fractal-based neurostimulation micro electrodes

Park, H, Takmakov, P., and Lee, H. Electrochemical evaluations of fractal microelectrodes for energy efficient neurostimulation. Scientific Reports, 8, 4375, 2018.

Prevention of Pt-corrosion of micro electrodes using a graphene monolayer

Park, H., Zhang, S., Steinman, A., Chen, Z., and Lee, H., Graphene prevents neurostimulation-induced platinum dissolution in fractal microelectrodes. 2D Materials, 6,035037, 2019.

In vivo evaluation of novel neural interfaces

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