Potential projects proposed by Purdue Engineering faculty

Project proposals are grouped by interdisciplinary area, and projects can appear under multiple areas.

Autonomous and Connected Systems

Beyond Model-Free: Leveraging Model-Based Reinforcement Learning for Software Systems and Computer Networks Optimization

AI-Enabled Resilient Freight Optimization and Responsive Network for Hazardous and Time-Sensitive Materials

Accelerating Piezotronic Material Discovery Using AI

Algorithm-Hardware Co-design of Robotic Vision-Language-Action Models

Can AI Agents Learn to Collude? Emergence, Detection, and Mitigation

Computational Optics for Near Field Imaging

Contextual AI for Materials: Integrating PINNs, Generative Models, and NLP for Data-Scarce Discovery

Cybersecurity in Space Domain Awareness and Exploration

FLEX: Facilitating Lean and Efficient X-operations in Multi-Robot and Multi-Human Collaborative Manufacturing

Generative AI Models and LLMs for Transportation Cybersecurity

Integrated Microscopy – Simulation Data Analytics for AI-Guided Advanced Materials and Devices

Learning and Control for Intelligent Interaction Between Humans and Autonomous Systems

Realizing Safe and Robust Autonomy through Exploitable Compliance

Worker-AI Teaming in the Construction Industry of the Future

CISLunar (Space science and Engineering)

Bioremediating Lunar Regolith through Controlled Environment Agriculture

Cybersecurity in Space Domain Awareness and Exploration

In-Space Robotic Assembly of Large Composite Structures

Micro-, Nano-, and Quantum Engineering

AI Driven Autonomous Synthesis of Sustainable Semiconductors for 3D-HI for High Performance Computing

AI-Guided Processing of Advanced Materials and Devices

Accelerated Fabrication of Meso-Structured Materials: Enabling Novel Properties for Impactful Engineering Application

Accelerated Neural Network Quantum States with Probabilistic Computing

Accelerating Piezotronic Material Discovery Using AI

Additive Manufacturing of Advanced High Strength Al Alloys

Computational Optics for Near Field Imaging

Contextual AI for Materials: Integrating PINNs, Generative Models, and NLP for Data-Scarce Discovery

Electrohydrodynamics of Nonequilibrium Patterns and Emergence of Organized States in Confined Liquids

First Principles and Machine Learning Guided Search for Extreme Thermal Conductivity Materials

Imposing Constraints on Quantum Machine Learning Models

Integrated Microscopy – Simulation Data Analytics for AI-Guided Advanced Materials and Devices

Large-Scale Atomistic Simulations of Cavitation-Induced Plasma and Sonoluminescence

Machine Learning-Guided Development of Advanced Radiative Cooling Coatings

Navigating Tortuous Energy Landscape Topographies using Atomistic Simulations, AI Models, and Targeted Experiments

Next Generation Biomanufacturing of Therapeutics

Next-Generation Interconnect Materials for 3D Heterogeneous Integration

Particles, Polymers, and Compliant Boundaries at the Intersection of Fluid Mechanics and Soft Matter

Photonic Integrated Circuits from Hybrid Metamaterial Thin Films

Transparent Radiative Cooling Coatings

Understanding Selective Membranes for Resource Recovery and Water Safety

mRNA Stability and Structural Hierarchy

Innovation and Making

A Networked Dynamical Systems Approach to Enable Optimal Design for Product Evolution (DfPE)

AI-Guided Processing of Advanced Materials and Devices

Accelerating Piezotronic Material Discovery Using AI

Electrohydrodynamics of Nonequilibrium Patterns and Emergence of Organized States in Confined Liquids

Transparent Radiative Cooling Coatings

Defense related projects (for US citizens only)

Computational Optics for Near Field Imaging

Multiphase Detonation Physics for Next-Generation Propulsion

Redictive Science for Group Combustion in High-Speed Multiphase Flows

Human-Machine/Computer Interaction, Human Factors, Human-Centered Design

AI, Ethics, and Education

Accelerating Piezotronic Material Discovery Using AI

Dissecting the Impacts of PFOA Exposure on the Gut-Brain Axis

Integrated Microscopy – Simulation Data Analytics for AI-Guided Advanced Materials and Devices

Worker-AI Teaming in the Construction Industry of the Future

Power, Energy, and the Environment

AI-Guided Processing of Advanced Materials and Devices

Accelerating Piezotronic Material Discovery Using AI

Bioremediating Lunar Regolith through Controlled Environment Agriculture

Can AI Agents Learn to Collude? Emergence, Detection, and Mitigation

Contextual AI for Materials: Integrating PINNs, Generative Models, and NLP for Data-Scarce Discovery

Designing Scalable and Resilient Closed-Loop Future Battery Manufacturing Networks

Dissecting the Impacts of PFOA Exposure on the Gut-Brain Axis

Electrohydrodynamics of Nonequilibrium Patterns and Emergence of Organized States in Confined Liquids

First Principles and Machine Learning Guided Search for Extreme Thermal Conductivity Materials

Large-Scale Atomistic Simulations of Cavitation-Induced Plasma and Sonoluminescence

Machine Learning-Guided Development of Advanced Radiative Cooling Coatings

Mechanics of Mixed Ionic–Electronic Conductors

Model-Based Deep Learning Accelerated Cosmic Ray Muon Tomography for Real-Time Automated Monitoring of Advanced Microreactors

Modeling and Control of Dynamic Electric Load Demands from Data Centers

Navigating Tortuous Energy Landscape Topographies using Atomistic Simulations, AI Models, and Targeted Experiments

Rheology of Concentrated Particle Suspensions

Sulfur‑Rich Polymer/2D Composites for Stable Solid–Electrolyte Interfaces in Li Metal Batteries

Transparent Radiative Cooling Coatings

Understanding Selective Membranes for Resource Recovery and Water Safety

Data and Engineering Applications

Beyond Model-Free: Leveraging Model-Based Reinforcement Learning for Software Systems and Computer Networks Optimization

A Hybrid Mechanistic Agent-Based Modeling and Machine Learning Approach for Epidemic Mitigation Design

A Networked Dynamical Systems Approach to Enable Optimal Design for Product Evolution (DfPE)

AI-Enabled Resilient Freight Optimization and Responsive Network for Hazardous and Time-Sensitive Materials

AI-Guided Processing of Advanced Materials and Devices

Accelerating Piezotronic Material Discovery Using AI

Advanced Analytics in Precision Health

Can AI Agents Learn to Collude? Emergence, Detection, and Mitigation

Computational Optics for Near Field Imaging

Computer Vision and Machine Learning Enabled Prediction of Two-Phase Flow and Heat Transfer

Contextual AI for Materials: Integrating PINNs, Generative Models, and NLP for Data-Scarce Discovery

Cross-Layer Resilience and Security for Autonomous Transportation Networks

Data-Driven Compact Thermal Propulsion Systems for High-Energy-Density Fuels

Designing Scalable and Resilient Closed-Loop Future Battery Manufacturing Networks

Electrohydrodynamics of Nonequilibrium Patterns and Emergence of Organized States in Confined Liquids

FLEX: Facilitating Lean and Efficient X-operations in Multi-Robot and Multi-Human Collaborative Manufacturing

First Principles and Machine Learning Guided Search for Extreme Thermal Conductivity Materials

Impacts of Social Determinants of Health on Infectious Diseases: Multi-Scale Modeling and Control

Imposing Constraints on Quantum Machine Learning Models

Integrated Microscopy – Simulation Data Analytics for AI-Guided Advanced Materials and Devices

Machine Learning-Guided Development of Advanced Radiative Cooling Coatings

Machine Learning-Mediated Whole-Body Mouse Imaging of Therapeutic Cells/Drugs

Machine-Learning Based Molecular Dynamics of Biotherapeutics

Model-Based Deep Learning Accelerated Cosmic Ray Muon Tomography for Real-Time Automated Monitoring of Advanced Microreactors

Multi-Scale Computational Modeling of Cerebrospinal Fluid Flow and Transport

Navigating Tortuous Energy Landscape Topographies using Atomistic Simulations, AI Models, and Targeted Experiments

Particles, Polymers, and Compliant Boundaries at the Intersection of Fluid Mechanics and Soft Matter

Rheology of Concentrated Particle Suspensions

Sensor Design for Pharmaceutical and Biomedical Applications

Security and Privacy

Computational Optics for Near Field Imaging

Cross-Layer Resilience and Security for Autonomous Transportation Networks

Cybersecurity in Space Domain Awareness and Exploration

Generative AI Models and LLMs for Transportation Cybersecurity

Engineering-Medicine

A Hybrid Mechanistic Agent-Based Modeling and Machine Learning Approach for Epidemic Mitigation Design

Addressing Fertility by Probing Mechanics and Mechanobiology of Mammalian Eggs

Advanced Analytics in Precision Health

Bioinspired Materials for Surgical Adhesive or Sealant Applications

Dissecting the Impacts of PFOA Exposure on the Gut-Brain Axis

Drug Transport in In Vitro Subcutaneous Tissues

Electrohydrodynamics of Nonequilibrium Patterns and Emergence of Organized States in Confined Liquids

Impacts of Social Determinants of Health on Infectious Diseases: Multi-Scale Modeling and Control

Machine Learning-Mediated Whole-Body Mouse Imaging of Therapeutic Cells/Drugs

Machine-Learning Based Molecular Dynamics of Biotherapeutics

Multi-Scale Computational Modeling of Cerebrospinal Fluid Flow and Transport

Nanotechnology Platform for Combined Radio-Photodynamic and Immunotherapy of Cancer

Next Generation Biomanufacturing of Therapeutics

Particles, Polymers, and Compliant Boundaries at the Intersection of Fluid Mechanics and Soft Matter

Sensor Design for Pharmaceutical and Biomedical Applications

mRNA Stability and Structural Hierarchy

Others

Beyond Model-Free: Leveraging Model-Based Reinforcement Learning for Software Systems and Computer Networks Optimization

A Hybrid Mechanistic Agent-Based Modeling and Machine Learning Approach for Epidemic Mitigation Design

AI, Ethics, and Education

Accelerated Fabrication of Meso-Structured Materials: Enabling Novel Properties for Impactful Engineering Application

Accelerated Neural Network Quantum States with Probabilistic Computing

Addressing Fertility by Probing Mechanics and Mechanobiology of Mammalian Eggs

Biomechanics of Plant Growth

Computational Optics for Near Field Imaging

Data-Driven Compact Thermal Propulsion Systems for High-Energy-Density Fuels

Impacts of Social Determinants of Health on Infectious Diseases: Multi-Scale Modeling and Control

Insects and Bioinspiration: Learning from Cicadas and Honey bees

Integrated Microscopy – Simulation Data Analytics for AI-Guided Advanced Materials and Devices

Large-Scale Atomistic Simulations of Cavitation-Induced Plasma and Sonoluminescence

Future Manufacturing

A Networked Dynamical Systems Approach to Enable Optimal Design for Product Evolution (DfPE)

AI and Advanced 3D Imaging for Real-Time Anomaly Detection

AI-Guided Processing of Advanced Materials and Devices

Accelerated Fabrication of Meso-Structured Materials: Enabling Novel Properties for Impactful Engineering Application

Accelerating Piezotronic Material Discovery Using AI

Additive Manufacturing of Advanced High Strength Al Alloys

Computational Optics for Near Field Imaging

Contextual AI for Materials: Integrating PINNs, Generative Models, and NLP for Data-Scarce Discovery

Designing Scalable and Resilient Closed-Loop Future Battery Manufacturing Networks

Electrohydrodynamics of Nonequilibrium Patterns and Emergence of Organized States in Confined Liquids

FLEX: Facilitating Lean and Efficient X-operations in Multi-Robot and Multi-Human Collaborative Manufacturing

In-Space Robotic Assembly of Large Composite Structures

Integrated Microscopy – Simulation Data Analytics for AI-Guided Advanced Materials and Devices

Next Generation Biomanufacturing of Therapeutics

Next-Generation Interconnect Materials for 3D Heterogeneous Integration

Rheology of Concentrated Particle Suspensions

Understanding Selective Membranes for Resource Recovery and Water Safety

Worker-AI Teaming in the Construction Industry of the Future

Smart City, Infrastructure, Transportation

AI-Enabled Resilient Freight Optimization and Responsive Network for Hazardous and Time-Sensitive Materials

Accelerating Piezotronic Material Discovery Using AI

Cross-Layer Resilience and Security for Autonomous Transportation Networks

Generative AI Models and LLMs for Transportation Cybersecurity

Mechanics of Mixed Ionic–Electronic Conductors

Worker-AI Teaming in the Construction Industry of the Future

Integrated Neuroscience and Engineering

Dissecting the Impacts of PFOA Exposure on the Gut-Brain Axis

Mechanics of Mixed Ionic–Electronic Conductors

Multi-Scale Computational Modeling of Cerebrospinal Fluid Flow and Transport

Protein Aggregation and Neurocircuit Dysfunction in Central Nervous System Diseases

Worker-AI Teaming in the Construction Industry of the Future