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Recent News
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October 2, 2025 Congratulations to Baggie Nyande, Samir Diab, Helen Yao, Richard Lakerveld, and Zoltan Nagy on their paper "Crystallization in the presence of impurities: mechanisms, models and controls," which has been selected as an Editor's Choice in Chemical Engineering Research and Design!
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October 1, 2025 A select group of Purdue engineering and pharmacy graduate students are advancing Indiana's biopharmaceutical workforce training opportunities through the BioTrain Fellows program. Nate Michael from our research group, who is among the fellows working to strengthen the region's biopharmaceutical manufacturing workforce.
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September 17, 2025 Hemalatha Kilari was recently highlighted during Purdue's National Postdoctoral Appreciation Week. Hema serves as Vice President of the Purdue Postdoctoral Association. Her dedication to both research excellence and postdoctoral community leadership continues to distinguish her work.
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June 17, 2025 "Prof. Nagy has been elected as an External Member of the Hungarian Academy of Sciences (MTA) - one of the highest scholarly honors bestowed by Hungary's permier scientific institution!
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May 15, 2025 "Hybrid rule-based and optimization-driven framework for the synthesis of end-to-end optimal pharmaceutical processes"
was published by Yash Barhate, Daniel J. Laky, Daniel Casas-Orozco, Gintaras V. Reklaitis, and Zoltan K. Nagy in AIChE Journal.
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May 14, 2025 "A hybrid system for design space estimation in a rotary tablet press"
was published by Mohammad Shahab, Sunidhi Bachawala, Marcial Gonzalez, Zoltan Nagy, and Gintaras Reklaitis in International Journal of Pharmaceutics.
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April 07, 2025 Congratulations to Yash Barhate for winning the prestigious Magoon Award for Research excellence awarded by Purdue University College of Engineering and Davidson School of Chemical Engineering.
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April 18, 2025 Congratulations to all the authors of the paper 'Using PharmaPy with Jupyter Notebook to teach digital design in pharmaceutical manufacturing' ,
whose work has been recognized as one of the top-viewed articles in the Computer Applications in Engineering Education Journal.
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April 18, 2025 Congratulations to all the authors of the paper 'Techno-economic analysis of dynamic, end-to-end optimal pharmaceutical campaign manufacturing using PharmaPy' ,
whose work has been recognized as one of the top-viewed articles in the AIChE Journal.
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April 10, 2025 Attila Csathy presented his research at the 'Spring Undergraduate Research Conference - 2025', Purdue University!
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February 25, 2025 Prof. Nagy's startup Crystallization Systems Technology Inc. (CrySyst)
was recently featured on
Purdue University's Newsletter. The startup offers innovative crystallization monitoring, modeling and control software solutions to address process development challenges
across industries. The framework's foundation has been based on the innovative research done within the group in the last decade.
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January 27, 2025 "Digital Design of an Integrated Continuous Crystallization,
Wet Milling and Classification System with Recycle for Purity and Crystal Size Distribution Control"
was published by Rojan Parvaresh and Zoltan K Nagy in Industrial & Engineering Chemistry Research.
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December 20, 2024 Congratulations to Yash Barhate for receiving the prestigious Bilsland Dissertation Fellowship!
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October 29, 2024 Current and alumni members of the CryPTSys group
at
AIChE 2024 in San Diego, California!
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October 29, 2024 Congratulations to Yash Barhate for winning a PD2M Student Award at AIChE!
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October 29, 2024 Congratulations to Montgomery Laky for winning a Separations Division Graduate Student Award at AIChE!
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October 7, 2024 Congratulations to Prof. Zoltan Nagy for winning the prestigious "2024 Excellence and Impact Award (Manufacturing)", announced by
AIChE's PD2M Forum!
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September 26, 2024 Congratulations to Montgomery Laky for recognition as a MIT Chemical Engineering Rising Star!
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September 17, 2024 Congratulations to Megha Das for winning the prestigious centennial award for exceptional
performance in her first-year of Graduate School!
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August 15, 2024 Congratulations to Monika Neal for winning 1st best
Overall Poster at the 33rd annual Purdue GSO Symposium!
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August 15, 2024 Congratulations to Montgomery Laky for winning 1st best
Presentations in Biotech & Pharmaceuticals at the 33rd annual Purdue GSO Symposium!
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August 2, 2024: Inyoung Hur successfully defended her thesis:
"Model-based design and control of an integrated purification platform for continuous pharmaceutical manufacturing". She was advised by Prof.
Zoltan K. Nagy.
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July 25, 2024 Aishwarya Menon (left) and Urvi Mathur (right)
presented their summer work at SURF!
 
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June 20, 2024 "Process Intensification via End-to-End Continuous
Manufacturing of Atorvastatin Calcium Using an Integrated, Modular
Reaction-Crystallization-Spherical Agglomeration-Filtration-Drying Process"
was published by Rojan Parvaresh and Zoltan K Nagy in Organic Process Research &
Development.
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June 17, 2024: Rojan Parvaresh successfully defended her thesis:
"Process Intensification of Integrated Continuous Crystallization Systems with
Recycle". She was advised by Prof.
Zoltan K. Nagy.
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June 11, 2024 "Integrated Continuous Crystallization–-Spherical
Agglomeration (CCSA) Process for the Intensified Manufacturing of Atorvastatin
Calcium"
was published by Rojan Parvaresh, Shumaiya Ferdoush, Shivani Kshirsagar, Marcial
Gonzalez, and Zoltan K Nagy in Crystal Growth and Design.
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June 2, 2024 CryPTSys group delivers a workhop on "Digital design
of pharmaceutical processes using PharmaPy" at the joint ESCAPE34-PSE24 conference
in Florence, Italy!
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May 16, 2024 Congratulations to Montgomery Laky for winning the
2024 Marilyn Forney Trailblazer Award!
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May 15, 2024 Congratulations to Aishwarya Menon and Urvi Mathur for
getting the Summer Undergraduate Research Fellowhip (SURF)!
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April 16, 2024 Congratulations to Inyoung and Montgomery for
winning the Graduate Student Recognition Award!
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April 15, 2024 CryptSys Group celebrates the union of Dr. Dan and
Montgomery, and bids a fond farewell to Aybala, whose remarkable journey with us has
inspired us all. Wishing them joy and success on their new journeys!
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April 4, 2024 "OpenCrystalData: An open-access particle image
database to facilitate learning, experimentation, and development of image analysis
models for crystallization processes"
was published by Yash Barhate, Christopher Boyle, Hossein Salami, Wei-Lee Wu, Nina
Taherimakhsousi, Charlie Rabinowitz, Andreas Bommarius, Javier Cardona, Zoltan K.
Nagy, Ronald Rousseau, Martha Grover in
Digital Chemical Engineering.
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March 29, 2024 "Semicontinuous Blending of Pharmaceutical
Ingredients and the Impact of Process Parameters on the Blending Performance of an
Integrated Feeder Blender Operating Semicontinuously"
was published by Sumit Kumar, Yan-Shu Huang, Zoltan Nagy, Gintaras V Reklaitis,
Marcial Gonzalez, Paul Mort in
Advances in Materials Science and Engineering.
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March 11, 2024 "Process Development and Kinetic Analysis in the
Green Synthesis of Lomustine"
was published by Giulia Murbach-Oliveira, Ilke Akturk, Zoltan Nagy, David H Thompson
in
Organic Process Research & Development.
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February 16, 2024 Congratulations to Ilke for Being Selected as one
of the five Finalist in the Dauch Center Digital Transformation Competition!
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February 13, 2024 Monika, Montgomery, Ilke, Megha, Meng-Hua at the
2024 GWEN
Symposium.
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February 9, 2024 "Data‐driven identification of crystallization
kinetics" was published by Baggie W Nyande, Zoltan K Nagy, Richard Lakerveld in
AIChE Journal.
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January 23, 2024 "Digital Design of an Agrochemical Crystallization
Process via Two-Dimensional Population Balance Modeling" was published by Wei-Lee
Wu, Christopher Chappelow, Navraj Hanspal, Paul A Larsen, Jasson Patton, Aaron
Shinkle, Zoltan K Nagy in Organic Process Research & Development.
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January 10, 2024 "Hybrid model development and nonlinear model
predictive control implementation for continuous dry granulation process" was
published by Yan-Shu Huang, Rexonni B Lagare, Phoebe Bailey, David Sixon, Marcial
Gonzalez, Zoltan K Nagy, Gintaras V Reklaitis in Computers & Chemical Engineering.
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December 29, 2023 "Population balance model enabled digital design
and uncertainty analysis framework for continuous crystallization of pharmaceuticals
using an automated platform with full recycle and minimal material use" was
published by Yash Barhate, Hemalatha Kilari, Wei-Lee Wu, and Zoltan K. Nagy in
Chemical Engineering Science.
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November 23, 2023 "Digital design of an integrated purification
system for continuous pharmaceutical manufacturing" was published by Inyoung Hur,
Daniel Casas-Orozco, Daniel Laky, Francesco Destro, and Zoltan K. Nagy in Chemical
Engineering Science.
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November 8, 2023 Current and alumni members of the CryPTSys group
at
AIChE
2023
in Orlando, Florida!
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October 1, 2023 "Developing a Modular Continuous Drug Product
Manufacturing System with Real Time Quality Assurance for Producing Pharmaceutical
Mini-Tablets" was published by Varun Sundarkumar, Wanning Wang, Madeline Mills,
Zoltan K. Nagy, and Gintaras Reklaitis in Journal of Pharmaceutical Sciences.
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September 25, 2023 "Manufacturing pharmaceutical mini-tablets for
pediatric patients using drop-on-demand printing" was published by Varun
Sundarkumar, Wanning Wang, Zoltan K. Nagy, and Gintaras Reklaitis in International
Journal of Pharmaceutics.
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September 19, 2023 "Sensor Fusion and Calibration-Based Adaptive
Image Analysis Procedure for In Situ Crystal Size Measurement" was published by
Wei-Lee Wu, Madeline M Mills, and Zoltan K. Nagy in Crystal Growth & Design.
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September 6, 2023 Montgomery, Ilke, Prof. Nagy, Yash, and Yung-Shun
at ISIC 2023 in Glascow, United Kingdom!
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August 21, 2023 "Techno‐economic analysis of dynamic, end‐to‐end
optimal pharmaceutical campaign manufacturing using PharmaPy," authored by Daniel
Casas‐Orozco et al., has been featured on the front cover of
AIChE journal,
Volume 69, No. 9
. Congratulations to all the authors!
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August 17, 2023 Congratulations to Montgomery Smith for winning 1st
best Overall Poster at the 32nd annual Purdue GSO Symposium!
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August 17, 2023 Congratulations to Yash Barhate for winning 5th
best Overall Poster at the 32nd annual Purdue GSO Symposium!
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July 6, 2023 Varun Sundarkumar successfully defended his thesis:
" Advancing Dropwise Additive Manufacturing of Pharmaceuticals by Incorporating
Continuous Processing, Novel Dosage Forms, and Industry 4.0 Capabilities ". He
was advised by Prof. Gintaras Reklaitis and Prof. Zoltan K. Nagy.
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July 5, 2023 Yan-Shu Huang successfully defended his thesis: "
Advanced Process Control and Digital Twin Development for Continuous Pharmaceutical
Manufacturing ". He was advised by Prof. Gintaras Reklaitis and Prof. Zoltan K.
Nagy.
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June 20, 2023 Hema, Inyoung, Prof. Reklaitis, Prof. Nagy, Varun,
and Daniel at ESCAPE 2023 in Athens, Greece!
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April 27, 2023 Congratulations to Yash Barhate for winning the
Purdue Chemical Engineering Centennial Award!
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April 27, 2023 Congratulations to Montgomery Smith for winning the
Purdue Chemical Engineering Outstanding Teaching Assistant Award 2023!
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April 3, 2023 Congratulations to Monika Neal for winning the
College of Engineering Magoon Teaching Award 2023!
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March 26, 2023 "Reaction kinetics determination and uncertainty
analysis for the synthesis of the cancer drug lomustine" was published by Daniel
Casas-Orozco, Daniel Laky, Jaron Mackey, Gintaras Reklaitis, and Zoltan K. Nagy in
Chemical Engineering Science.
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March 10, 2023 Sumit Kumar successfully defended his thesis:
"Improving Blend Uniformity and Process Monitoring to Achieve Robust Oral
Solids Manufacturing Processes ". He was advised by Prof. Gintaras Reklaitis
and Prof. Zoltan K. Nagy.
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February 16, 2023 "Considerations in Raman Spectroscopy for
Real-Time API Concentration Measurement at Tablet Press Feed Frame" was published by
Sumit Kumar, Zoltan K. Nagy, Gintaras V Reklaitis, Marcial Gonzalez in Journal of
Spectroscopy.
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February 7, 2023 Hema, Aybala, Montgomery, Ilke and Rojan at the
2023 GWEN Symposium. Congratulations to Montgomery for winning an international
travel grant!
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February 1, 2023 "Experimental Design for the Efficient
Determination of the Crystallization Kinetics of a Polymorphic System in Combined
Cooling and Antisolvent Crystallization" was published by Shivani Kshirsagar, Botond
Szilagyi, and Zoltan K. Nagy in Crystal Growth & Design.
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January 14, 2023 "Developing a virtual flowability sensor for
monitoring a pharmaceutical dry granulation line" was published by Rexonni Lagare,
Yan-Shu Huang, Zoltan K. Nagy, Gintaras Reklaitis, et al. in the Journal of
Pharmaceutical Sciences.
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January 1, 2023: "Continuous extraction of 2-chloroethyl isocyanate
for 1-(2-chloroethyl)-3-cyclohexylurea purification" was published by Jaron Mackey,
Zoltan K. Nagy, et al. in the Chemical Engineering and Processing - Process
Intensification journal.
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November 3, 2022: Prof. Zoltan Nagy received the
Named
Professorship
honor for his accomplishments and successes at Purdue.
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October 12, 2022: Shivani Kshirsagar successfully defended her
thesis: "Process Intensification Techniques for Combined Cooling and
Antisolvent Crystallization of Drug Substances". She was advised by Prof.
Zoltan K. Nagy.
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October 7, 2022: Wei-Lee Wu successfully defended his thesis:
"Process intensification through control, optimization, and digitalization of
crystallization systems". He was advised by Prof. Zoltan K. Nagy.
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August 1, 2022: Jaron Mackey successfully defended his thesis:
"MiniPharm: A Miniaturized Pharmaceutical Platform for Process
Development". He was advised by Prof. Zoltan K. Nagy.
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July 6, 2022: Daniel Laky successfully defended his thesis:
"Optimization Techniques for Pharmaceutical Manufacturing and Design Space
Analysis". He was advised by Prof. Gintaras Reklaitis, Prof. Carl Laird, and
Prof. Zoltan K. Nagy.
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