Professional Experience

• Postdoctoral Research Associate, Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, 5/2006 - 7/2009

Awards and Honors

• Annual Reviews Award, Biomedical Engineering Society, 10/2004
• Fred J. Benson Graduate Fellowship, Texas A&M University, 8/2001

Selected Publications

• Wan Q, Xu W, Yan J-l, Yokota H, Na S (2014) Distinctive subcellular inhibition of cytokine-induced Src by salubrinal and fluid flow. PLoS One 9(8) e105699., 8/2014
• Hamamura K, Minami K, Tanjung N, Wan Q, Koizumi M, Matsuura N, Na S, Yokota H (2014) Attenuation of malignant phenotypes of breast cancer cells through eIF2α-mediated Rac1 signaling. International Journal of Oncology 44(6):1980-1988., 4/2014
• Kim SJ, Wan Q, Cho E, Han B, Yoder MC, Voytik-Harbin SL, Na S (2014) Matrix rigidity regulates spatiotemporal dynamics of Cdc42 activity and vacuole formation kinetics of endothelial colony forming cells. Biochemical and Biophysical Research Communications 443(4):1280-1285., 1/2014
• Hamamura K, Zhang P, Zhao L, Shim JW, Chen A, Dodge TR, Wan Q, Shih H, Na S, Lin C-C, Sun HB, Yokota H (2013) Knee loading reduces MMP13 activity in the mouse cartilage. BMC Musculoskeletal Disorders. 14(1:312):1-11., 11/2013
• Shim JW, Hamamura K, Chen A, Wan Q, Na S, Yokota H (2013) Rac1 mediates load-driven attenuation of mRNA expression of mRNA expression of nerve growth factor beta in cartilage and chondrocytes. Journal of Musculoskeletal and Neuronal interactions. 13(3):372-379., 9/2013
• Wan Q, Cho E, Yokota H, Na S (2013) RhoA GTPase interacts with beta-catenin signaling in clinorotated osteoblasts. Journal of Bone and Mineral Metabolism. 31(5):520-532., 9/2013
• Wan Q, Kim SJ, Yokota H, Na S (2013) Differential activation and inhibition of RhoA by fluid flow induced shear stress in chondrocytes. Cell Biology International 37(6):568-576., 6/2013
• Wan Q, Cho E, Yokota H, Na S (2013) Rac1 and Cdc42 GTPases regulate shear stress-driven beta-catenin signaling in osteoblasts. Biochemical and Biophysical Research Communications 433(4):502-507., 4/2013
• Poh Y-C, Chowdhury F, Wu D, Ns S, Dundr M, Wang N (2012) Dynamic force-induced direct dissociation of protein complexes in a nuclear body in living cells. Nature Communications 3(866):1-10., 12/2012
• Chowdhury F, Na S, Li D, Poh Y-C, Tanaka TS, Wang F, Wang N (2010) Material properties of the cell dictate stress-induced spreading and differentiation in embryonic stem cells. Nature Materials 9(1):82-88., 10/2009
• Na S, Wang N (2008) Application of fluorescence resonance energy transfer and magnetic twisting cytometry to quantify mechanochemical signaling activities in a living cell. Science Signaling 1(34:pl1):1-9., 8/2008
• Na S, Collin O, Chowdhury F, Tay B, Ouyang M, Wang Y, Wang N (2008) Rapid signal transduction in living cells is a unique feature of mechanotransduction. Proceedings of the National Academy of Sciences of the USA 105(18):6626-6631., 5/2008

Expertise

cellular mechanotransduction, bone/cartilage disease and mechanobiology

Interests

in vitro/ex vivo/in vivo imaging, fluorescence resonance energy transfer (FRET), integration of microscopy and mechanical loading systmes