What is Biomechanics and Mechanobiology?

  • Investigate how mechanical forces affect biological systems. Apply engineering principles to understand how forces, motion, deformation, and fluid flow influence human health and disease.
  • Study biological mechanics across multiple scales. Examine how mechanics regulate cell behavior and tissue remodeling, organ function, and whole-body movement.
  • Integrate imaging, experiments, and computational modeling to address healthcare challenges. Quantify cardiovascular flow and transport, musculoskeletal movement, tissue loading, bone fracture, joint mechanics, and rehabilitation.

Impact on Engineering & Medicine

  • Improve clinical care through engineering solutions. Apply biomechanical insights to understand disease mechanisms, improve diagnosis, guide interventions, and optimize therapeutic outcomes.
  • Advance predictive and personalized medicine. Use patient-specific imaging and biomechanical modeling to predict disease progression, evaluate therapeutic strategies, and optimize interventions for individual patients.
  • Drive innovation in medical technologies. Inform the design and evaluation of medical devices, implants, and prostheses, including their interactions with the human body, and advance rehabilitation approaches and other engineering solutions for clinical applications.

Bone Biology and Mechanics Lab (BBML) - Joseph Wallace

The BBML is committed to improving our understanding of how the body works through innovative preclinical and clinical research. As our name implies, the lab focuses on bone mechanics (ability to effectively bear loads) and mechanobiology (how cells respond to mechanical stimuli to maintain and/or increase bone mass).

Cardiovascular Flow Modeling Laboratory - Vitaliy Rayz

The mission of the Cardiovascular Flow Modeling Laboratory (CFM Lab) is to improve diagnostics and treatment of cardiovascular disease by conducting engineering analysis of blood flow dynamics.

MCT Biomechanics Laboratory - Taeyoon Kim

The Molecular, Cellular and Tissue (MCT) Biometrics Laboratory uses cutting-edge computational models to focus on diverse mechanical behaviors of biological matter between cytoskeletal and tissue length scales.

Musculoskeletal Research and Innovation Lab - Deva Chan

The Chan Musculoskeletal Research and Innovation (MRI) Lab believes that understanding the early response to injury is critical to diagnosis, assessment, and intervention in life-altering diseases, including post-traumatic osteoarthritis and traumatic brain injury.