Postdoc position in Functional Genomics and Large Language Model
We are seeking applicants for a postdoc position that offers a unique and great opportunity of
interdisciplinary training in machine learning and functional genomics.
Interdisciplinary Research
This position is funded by the initiative of the Institute for Physical
Artificial Intelligence at Purdue University to support postdocs whose innovative projects in
artificial intelligence have the ability to make tangible impact on real-world problems. The project
combines cutting-edge computational approaches, especially state-of-the-art machine learning
techniques including deep neural networks and large language models (such as GPTs), with stateof-
the-art functional genomics approaches, including crop genomics, genome editing, and single
cell multiomics, to identify and characterize novel transcriptional regulatory mechanisms that
control traits of agronomic importance. This project thus offers a unique opportunity to train a
future leader in combining the strengths of modern biotechnology and computational tools to
address essential questions in life sciences including plant biology and crop sciences.
Cross-field Mentoring
The postdoc will partner with two advisors, who are from different
disciplines and have established collaborations, to apply artificial intelligence to improve
agriculture sustainability and productivity:
Prof. Ying Li's research program aims to advance the
basic understanding of genome-wide regulatory mechanisms controlling important crop
physiological traits, with the goal of providing a knowledgebase for modern crop breeding and
engineering efforts to improve agricultural productivity and crop resilience. Dr. Li's research
methodology is interdisciplinary and integrates functional genomics, systems biology, machine
learning, biochemistry, epigenetics, genetics, and plant physiology, using multiple experimental
systems ranging from the model plant Arabidopsis, horticultural crops (petunia, tomato, bean, and
grape), to row crops (maize). Dr. Li has become an internationally recognized expert in
chromatin regulation of plant metabolism, as evidenced by publications in high-ranking scientific
journals including Science, PNAS, and New phytologist and multiple million dollars support from
various federal agencies. The Li lab is located within the College of Agriculture, one of the
world's leading colleges of agricultural, food, life, and natural resource sciences. Purdue
Agriculture is ranked #3 in the U.S. and #5 in the world according to the 2023 QS World
University Rankings.
Dr. Li is dedicated to helping all her lab members to reach their full potential. She starts
with developing an understanding of the strengths and goals of each lab member and works with
them to achieve these goals. The success of Dr. Li's mentoring is evidenced by the many awards
won by the members in the Li Lab, multiple publications authored by Li lab members, and the
growth of Li lab academic tree by placing mentees into prestigious graduate programs (Yale,
Washington University in St. Louis, and Purdue), biotech industry, as well as tenure track faculty
position.
Prof. Jing Gao's research is in the general area of data and information analysis with a focus on data
mining and machine learning. In particular, she is interested in information veracity analysis, multisource
data analysis, knowledge graphs, text mining, generative AI, data and model efficiency,
fairness and interpretation, transfer learning, federated learning, crowdsourcing, data stream
mining, and anomaly detection. She is also interested in various data mining applications in
healthcare, social science, criminal justice, biology, transportation, and education. She has
published 1 book, 3 book chapters, and nearly 200 papers in prestigious scientific venues, including
KDD, SIGMOD, VLDB, NIPS, ICML, AAAI, IJCAI, EMNLP, WWW, WSDM, CIKM, SDM,
ICDM, ICDE, ECML/PKDD, and TKDE. Dr. Gao has a strong track record of mentoring
students. The PhD students who graduated from her lab have joined Pennsylvania State University,
Iowa State University, University of Georgia as faculty, Google Research, Alibaba DAMO
Academy, Tencent AI Lab, J.D. Research as research scientists, and Google, LinkedIn as software
engineers.
Dr. Gao's program is with Purdue Engineering College and ECE School. Purdue University hosts
one of the best Engineering Colleges in US. Its Engineering College is ranked #4 by U.S. News &
World Report. The ECE School is the largest academic unit at Purdue Engineering College and
also one of the largest ECE programs in the country. Purdue ECE has over 120 faculty members,
including 7 US National Academy of Engineering members, 42 IEEE Fellows, and a former IEEE
president. In U.S. News & World Report, Purdue ECE's Electrical Engineering program is ranked
#8 and its Computer Engineering program is ranked #10.
Competitve Support
The funded postdoc will be full-time staff and receive an annual salary of
$70,000 and benefits. Participating postdocs will also receive $2,500 for professional development
(e.g. attending conferences or workshops) and $50,000 to support their research. The position is
under yearly renewable contract, and the total funding is for two years and possible to be extended
for the 3rd year.
Required Qualifications
PhD degree in genetics, genomics, biology, plant sciences, computer
science, statistics or in any related field. Plant molecular biologists with prior experience in
molecular genomics and are interested in expanding skillset into machine learning, as well as
computational scientists who are looking to develop in-depth biological experimental skills, are
encouraged to apply.
Preferred Qualifications
We value demonstrated excellence in the following areas:
- Performing and/or analyzing functional genomics experiments
Competence with Unix environment, R, Python/perl, high performing cluster
3. Have taken coursework in calculus, linear algebra, probability and statistics, and possess
strong proficiency in mathematical thinking and abstract reasoning.
4. Cellular, biochemical, molecular experimental skills
5. Experience working with plant species in research settings
6. Excellent organization and communication skills
7. Curiosity that goes across disciplinary boundaries
8. Independence and leadership in research projects
- Competence with Unix environment, R, Python/perl, high performing cluster
- Have taken coursework in calculus, linear algebra, probability and statistics, and possess
strong proficiency in mathematical thinking and abstract reasoning.
- Cellular, biochemical, molecular experimental skills
- Experience working with plant species in research settings
- Excellent organization and communication skills
- Curiosity that goes across disciplinary boundaries
- Independence and leadership in research projects
How to apply:
This position is available in September 2024. Applications should be emailed to
lilabpurdue@gmail.com. . Please include a cover letter, an updated CV with skills and previous
education/research experience/publications, and the contacts of three references. Applications will
be reviewed on a rolling basis until the position is filled.