[BNC-all] Seminar: Hur Koser, Assistant Professor of Electrical Engineering, Yale University, 9/25/06 @ 2 PM in BRK 2001

[Annie Cheever]

Magnetic Liquids for Lab-on-a-Chip and Rapid Diagnostics Applications

Hür Köser
Assistant Professor of Electrical Engineering, Yale University

Monday, September 25, 2006
2:00 PM in the Birck Building, Room 2001

Ferrofluids are stable colloidal suspensions of 
nanosize ferromagnetic particles in either 
aqueous or oil-based media. They have found their 
way into a variety of applications, such as 
sealing, damping and blood separation; in dilute, 
functionalized forms, they have also been used as 
drug delivery and MRI contrast agents. These 
complex liquids offer attractive alternatives to 
moving mechanical components in miniaturized 
cooling, pumping and integrated 
micro-total-analysis-systems for chip-scale 
chemistry and biology. Water-based ferrofluids 
can also be made bio-compatible, rendering them 
useful in novel cell manipulation and sorting 
schemes. We have recently proposed, modeled and 
experimentally confirmed that ferrofluids can be 
actuated and pumped in closed-loop geometries, 
even within geometries of micro-scale devices. 
The pumping dynamics depend on the average 
nanoparticle size within the ferrofluid. If 
particles are functionalized with a receptor 
molecule, the entire volume of the ferrofluid 
becomes a pathogen sensor that can detect minute 
quantities of target antigens efficiently and 
effectively. We are working on creating portable, 
disposable, cheap and miniaturized sensor and 
diagnostic devices based on this dynamic effect. 
We also briefly report on the development of a 
novel, ferrofluid-based assay to study a large 
quantity of ligand-receptor interactions quickly 
and simultaneously, without the need for any wash 
cycles.

Dr. Koser obtained double B.S. degrees in 
Electrical Engineering and Physics from the 
Massachusetts Institute of Technology (MIT), a 
Master's of Engineering degree for his work on 
magnetic random access memory devices at IBM T. 
J. Watson Research Laboratory. He stayed at MIT's 
Electrical Engineering Department the get a Ph.D. 
in the field of Microsystems (2002). After a post 
doctoral work in microfluidics at the Research 
Laboratory of Electronics at MIT, he joined the 
Electrical Engineering Department at Yale 
University as an Assistant Professor in 2003, 
where he currently conducts research in micro and 
nanotechnology applications to biomedical 
engineering and power devices. Dr. Koser has 
recently received the NSF Career Award for his 
work on ferrofluid dynamics and will be on a 
prestigious Junior Faculty Fellowship (awarded by 
Yale University) during the next academic year to 
expand his work on ferrofluids. He is also the 
receipient of the 2003 Yale Information 
Technology Systems (ITS) Instructional Innovation 
Award and the Moore Award for the development of 
a microfluidics-based teaching laboratory.

Host:  Cagri Savran, Mechanical Engineering 
Department, (48601, savran at purdue.edu)
-- 

------------------------------------------------------------------------
Annie Cheever, Area Secretary                      
School of Electrical and Computer Engineering 
	                                                                 
 
acheever at purdue.edu
			  
Purdue University
Birck Nanotechnology Center, Room 2027
1205 West State Street
West Lafayette, IN  47907-1205

Phone: 765-496-8327     Fax: 765-496-6443
------------------------------------------------------------------------
-------------- next part --------------
An HTML attachment was scrubbed...
URL: /ECN/mailman/archives/bnc-all/attachments/20060922/654f7792/attachment-0001.html 
-------------- next part --------------
A non-text attachment was scrubbed...
Name: %Koser_FerrofluidsSemina#104
Type: application/applefile
Size: 137 bytes
Desc: not available
Url : /ECN/mailman/archives/bnc-all/attachments/20060922/654f7792/attachment-0001.bin 
-------------- next part --------------
A non-text attachment was scrubbed...
Name: Koser_FerrofluidsSemina#104
Type: application/octet-stream
Size: 1297583 bytes
Desc: not available
Url : /ECN/mailman/archives/bnc-all/attachments/20060922/654f7792/attachment-0001.obj