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ZADD - Zoonotic and Animal Disease Defense

Name:ZADD - Zoonotic and Animal Disease Defense
Project TitleDuration
Rift Valley Fever Modeling and Vulnerability Analysis2005-2007
Characterization of Avian Influenza Viruses in Live Bird Market Settings2005-2007
Evaluation of Mass-Scale Robotic ELISA Tests for Foot-and-Mouth Disease Using Sub-Genomic Replicons2005-2007
Development of New Targets for Antiviral Intervention and New Diagnostics to Detect Foot-and-Mouth Disease Virus Infection2005-2007
Innate Resistance as an Evolving Paradigm Against Select Agents of Livestock Species2005-2007
Development of a Rapid and Inexpensive Diagnostic Kit for Foot-and-Mouth Disease and Rift Valley Fever2005-2007
Evaluation of Immunogenicity of Candidate Rift Valley Fever Vaccines in Sheep2005-2007
Diagnosis of and Protection Against Infectious Brucella Aerosols2005-2007
UC Davis Wildlife Health Center: Avian Influenza Response Instructor Training Program2005-2007
Analysis and Utilization of CpG-Motif Oligonucleotides as Potential Poultry Immunostimulatory Agents Against Avian Influenza Challenge2005-2007
Candidate Rift Valley Fever Vaccines2005-2007
Development of Highly Sensitive Immunoassays and Reagents for Detection of Avian Influenza2005-2007
Role of Natural Killer Cells in FMDV in cattle-characterization and identification of modulation strategies2005-2007
Training to Heighten Awareness, Improve Surveillance, Sample Submission and Testing, and Encourage Reporting Compliance Among Producers2005-2007
Courseware Library on Foreign Animal & Zoonotic Disease High-Priority Agents and Issues2005-2007
Undergraduate/Professional and Graduate Student Fellowships to Enhance Capacity Consistent with DHS Mission2005-2007
Master's of Preventive Veterinary Medicine Student Fellowships2005-2007
Postgraduate Train-the-Trainers Program to Provide Credible Local Expertise Capable of Delivering Educational Programs to Improve Biosecurity, Surveillance, Sample Submission, Testing and Reporting Co2005-2007
Assessment of Key Projects2005-2007
Modify Existing Biosecurity Systems to Improve Resistance to Foreign Animal Threats While Improving Endemic Disease Control2005-2007
Commodity-Specific Educational Materials to Effectively Communicate Risks, Benefits and Approaches to Reducing Vulnerability to Foreign Animal & Zoonotic Diseases2005-2007
A Conference on the Science and Policies Associated with Carcass Disposal2005-2007
Review and Report on Current Disinfectants and Disinfection Procedures as They Relate to Foreign Animal & Zoonotic Disease, and Create a Web-Based Reference Manager for Updating and Reporting the Find2005-2007
Create a System to Identify Underserved Communities in the Four Border States and to Define Key Social Communication Systems Capable of Fostering Effective Communication about Foreign Animal and Zoono2005-2007
Improve Crisis Management and Media Interface Relevant to Foreign Animal and Zoonotic Disease Incursions2005-2007
Risk Communication/Outreach: Develop a System of Communication Between County Advisors and Local Media Outlets in Preparation of an Accidental or Introduced Foreign and Zoonotic Disease2005-2007
Spatial Epidemiologic Modeling of Foot-and-Mouth Disease in the United States2005-2005
Middleware and Grid Computing2005-2007
Spatial Data Acquisition and Analysis2005-2007
Integrated Modeling and Transportation Modeling2005-2007
Improving the Epidemilogic Engine of Current Foot-and-Mouth Disease Models2005-2007
A Simulation Supported Exercise Environment to Support Foreign Animal and Zoonotic Disease Defense Strategic Planning and Training Needs2005-2007
Vulnerability Assessment of Foot-and-Mouth Disease and Rift Valley Fever2005-2007
Gap Analysis to Support Animal Biodefense Strategic Planning2005-2007
Economic and Environmental Consequences of Carcass Disposal2005-2007
Developing a Scalable and Generic Epidemiologic Model2005-2007
Economic Studies Regarding Comprehensive Decision Making for Agricultural Biosecurity2005-2007
Economic Analysis of Foreign Animal and Zoonotic Disease Policies2005-2007
Risk Assessment and Analysis for Improved Planning for Foreign Animal and Zoonotic Disease Defense2005-2007
Systems Design Requirements for an Integrated Modeling Environment2005-2007
Refinement of Livestock Transportation Modeling and Improved Middleware for Linkage with Epidemiologic Models2005-2007
Epidemic Models of FMD Introduction and Spread in the High Plains2005-2007
Avian Influenza Economic Modeling2005-2007
TEST-Rift Valley Fever: Develop modern detection systems, animal vaccines, and innate genetic resistance markers.
TEST-Develop modern, knowledge-based diagnostic reagents for incorporation in to a spectrum of assays from high-throughput surge-capacity robotic diagnostic tests to inexpensive, rapid, and accurate d
Y6 BIO 1-4- Identify candidate genes for host resistance to RVF using a laboratory animal model to develop livestock genomic tools
TEST-Evaluate the Economic implications various policy and management options have on the preventions, management, and recovery of a FAZD outbreak.
Y6 BIO 2-3- Screen genomic variations in bovine toll-like receptor and Cathlecidin (CATHL) genes as candidates for host resistance to FMD and RVF
TEST-Develop and pilot test a zoonotic public health curriculum and outreach program for minority operators and underserved populations.
BIO 1-1a- Develop effective and rapidly acting Rift Valley fever vaccine candidates2007-present
BIO 3-3- Define relevant chicken B lymphocyte epitopes in avian influenza viruses2007-present
Foot-and-mouth disease: Develop novel technologies to enhance detection of and protection against foot-and-mouth disease virus.2007-2008
BIO 4-1- Develop molecular platforms for mobilizing rapid antibody and NK cell responses to threat agents2007-present
IAS 5-2- Develop and deliver the national avian influenza model2007-present
IAS 7-2- Evaluate economic implication of policy and management options for preventing, managing, and recovering from foreign animal and zoonotic disease2007-present
IAS 8-1- Develop and evaluate the integrated DSS software linking related models through functional middleware and a user-friendly interface for utility2007-present
EOS 9-1- Increase the federal and private sector workforce pool of expertise with awareness and experience with foreign animal and zoonotic disease control, including preparing students from minority 2007-present
EOS 10-1- Develop education and outreach programs on foreign animal and zoonotic diseases, including distance education and training for physicians and health workers2007-2009
EOS 11-1- To deliver to national audiences the Train-the-Trainer programs on risk communication developed in the first triennium2007-present
IAS 8-2- Develop and organize relevant databases required as inputs for the Decision Support System2007-present
BIO 1-1b- Develop effective and rapidly acting Rift Valley fever vaccine candidates2007-2009
BIO 1-3- Develop a rapid and inexpensive diagnostic kit for Rift Valley fever2007-2009
BIO 2-1- Develop immune system modulation strategies to contribute to the development of next-generation effective and rapidly acting FMD vaccine technologies.2007-present
BIO 2-2a- Develop modern, knowledge-based diagnostic reagents for incorporation into a spectrum of assays from high-throughput surge-capacity robotic diagnostic tests to inexpensive, rapid, and accura2007-2009
BIO 3-4- Improve influenza A diagnostic testing methodologies for free-flying birds2007-present
BIO 3-5- Derive comprehensive and informative molecular signatures of avian influenza viral infection in chickens using genomics platforms2007-present
BIO 4-2b- Create integrated biomarker-specific biosignature, multiple select agent specific and/or universal biosignature detection arrays2007-present
BIO 2-2b Develop method to produce new foot-and-mouth vaccines based on replication of defective genomes2007-2008
IAS 5-3- Rift Valley fever modeling and vulnerability analysis2007-present
IAS 5-4- Develop a multiple scenario evaluation model for foot-and-mouth disease2007-present
IAS 5-5- Assess impact of wildlife reservoirs in outbreaks of foreign animal and zoonotic disease in animal populations using quantitative modeling2007-present
IAS 6-1- To develop a prototype Dynamic Preparedness System for training and operational for use in emergency response incident command centers2007-present
career development
IAS 7-1- Evaluate the economic implications various policy and management options have on the prevention, management, and recovery of a FAZD outbreak2007-present
IAS 8-3a- Develop, test, evaluate, and implement multi-purpose analytic platforms for modeling families of threats2007-present
IAS 8-3b- Develop, test, evaluate, and implement multi-purpose analytic platforms for modeling families of threats2007-present
IAS 8-4- Information and Analysis Systems theme leader2007-2009
New and Emerging Issues- Visual Analytics: Create pilot visual analytic environments for both Rift Valley fever modelers and for policy makers 2009-present
EOS 9-2- Implement a DHS Scholars and Fellows Program to include minorities2007-present
EOS 10-2a- Develop education and outreach programs for minority operations through collaboration with minority-serving institutions2007-2009
EOS 10-2b- Develop and pilot test a zoonotic public health curriculum and outreach program for minority operators and underserved populations2007-present
EOS 10-3- Maintain and expand the FAZD Center Core Resources Library2007-2009
EOS 11-2- Develop and deliver educational materials on risk communication for professional organizations, governmental agencies, and first responders for foreign animal and zoonotic disease2007-present
EOS 11-3- Host an Animal Health Network (formerly County Animal Security and Health Network - CASHN) technology transfer conference as a method used to solve the practical problem of reaching non-comm2007-present
EOS 11-4- Develop Hispanic educational curriculum and workshops targeted at agriculture workers providing animal health care on a routine basis. The workshops will focus on defending against accident2009-present
Y6 BIO 1-1- Develop livestock RVF vaccines with DIVA capability for commercialization
Y6- BIO- Finding a novel mammalian gene for resistance to Rift Valley fever virus2010-present
Y6- EOS- K-12 Zoonotic Disease Curriculum Development2010-present
Y6- IAS- Impact of Climate on the Introduction of a Zoonotic Disease in the United States: A Focus on Rift Valley Fever2010-present
Y6- BIO- Differentiation of foot-and-mouth disease virus in infected and vaccinated animals using a competitive ELISA based on an immunodominant linear B-cell isotope of the 3B protein2010-present
Y6- IAS- Livestock-wildlife interactions in a western rangeland setting: impacts on epidemiologic models of FMD2010-present
Y6- IAS- Critical comparison of contact assumptions in spatially explicit disease models2010-present
Y6- EOS- Increasing Public Awareness of Emerging Vector-Borne Diseases2010-present
Y6 BIO 1-2- Evaluate the immunogenicity of candidate Rift Valley fever vaccines in sheep2009-present
Y6 BIO 4-2- Create integrated biomarker-specific biosignature, multiple select agent specific arrays, and/or universal biosignature detection arrays2009-present
Y6 BIO 2-1- Test novel vaccines and biotherapeutics cytokine adjuvants to optimize the induction of protective mucosal immunity against FMD in swine and cattle2009-present
Y6 BIO 4-1- Create integrated biomarker-specific biosignature, multiple select agent-specific and/or universal biosignature detection arrays2009-present
Y6 IAS 5-1a- Consequences of Zoonotic Diseases on Public Health: Develop and Deliver the National Avian Influenza Model2009-present
Y6 IAS 7-1a- Analysis of Decisions, Options, and Risks: Develop FMD-based multiple scenario evaluation models2009-present
Y6 IAS 7-1b- Analysis of Decisions, Options, and Risks: Assess impact of wildlife reservoirs in outbreaks of foreign animal disease populations in FAZD outbreaks using quantitative modeling2009-present
Y6 IAS 7-1f- Analysis of Decisions, Options, and Risks: Develop and organize relevant databases as inputs for the DSS2009-present
Y6 BIO 3-1- Develop improved H5 ELISA and fluorescent microsphere-based multiplex diagnostics for chickens and turkeys2009-present
Y6 EOS 10-4- Develop a web-based national curriculum for train-the-trainers in FAZDs2009-present
Y6 EOS 11-5- Develop youth education and job-training with public health and regulatory emphases of zoonotic and exotic diseases2009-present
Y6 EOS 10-2- Develop modern education materials and innovative delivery mechanisms for FAZD risk assessment and risk management for future industry and animal/public health officials2009-present
Y6 IAS 5-1b- Consequences of Zoonotic Diseases on Public Health: Develop and Deliver the National Rift Valley Fever Model
Y6 IAS 7-1e- Evaluate implication of policy and management options for preventing, managing, and recovering from a Rift Valley fever event2010-present
Y6 EOS 11-4- Develop Hispanic educational curriculum and workshops targeted at agricultural workers providing animal health care on a routine basis2010-2011
Y6 EOS 8-1- Increase the public and private sector homeland security professional workforce pool with effectively trained FAZD defense practitioners, researchers, and educators2009-present
Y6 EOS 8-2- Promote HS-STEM opportunities in FAZD critical disciplines for minorities and Minority Serving Institutions (MSIs) afforded by DHS Career Development Program funding and additional externa2009-present
Y6 IAS N&E- Effect of meteorological and environmental factors on the probability of avian influenza viruses (AIV) carriage by wild birds2009-present
Y6 IAS 7-1c- Evaluate the economic implications of policy and management options on the preventions, and management of FAZD outbreak plus recovery2009-present
Y6 IAS 6-2a- Develop and evaluate software linking disease and economic models through functional middleware and user friendly interface2009-present
Y6 IAS 6-2b- Develop multi-purpose analytic and decision-support platform2009-present
Y6 EOS 10-1- Present Train-the-Trainer programs on FAZD risk communication to national audiences2009-present
Y6 EOS 10-3- Establish a national emergency response network that includes MSIs and addresses underserved rural farmers and ranchers (Animal Health Network- AHN)2009-present
Y6 IAS 5-2- Web-based Bio-situational Common Operating Picture2009-present
Y6 IAS 14-N&E- Prevalence and Characterization of Influenza in Wild Mammals from the US2010-2011
Proj. 1a: Determine Safety and Efficacy of a Newcastle Disease Virus (NDV)-Vectored Avian Influenza Virus (AIV) in Poultry2010-2012
Proj. 1b: Novel Vaccine Platforms: H3N2 SIV Protection of Swine as a Proof-of-Concept2010-2012
Proj. 2: Rift Valley Fever (RVF)- Expression of RVF Virus Proteins as Subunit Vaccines and the Development of Reference Cellular and Humoral Immune Response Assays2010-2012
Proj. 3a: Pathogen Detection and Discovery2010-2012
Proj. 3b: Repository for Clinical Samples at Kansas State Veterinary Diagnostics Laboratory2010-2012
Proj. 4: Epidemiological Study of Persons with Intense Exposure to Ruminants for Rift Valley Fever Virus Infection2010-2012
Proj. 5: Wildlife Studies- Use of resident Canada Geese as a sentinel system to document and map avian influenza transmission within the United States2010-2012
Proj. 6: Data Collection for Developing a Rift Valley Fever Assessment Model2010-2012
Proj. 7a: Develop and Deliver Web Based Continuing Education Courses for Veterinarians and Graduate Students2010-2012
Proj. 7b: Coordination of Animal Emergency Response Materials with the Texas A&M FAZD Center2010-2012
Proj. 8a: Laboratory Animal Medicine Residency Program2010-2012
Proj. 8b: School of Journalism Program in Risk and Crisis Communication 2010-2012
Proj. AH1: Vectored Herpesvirus Vaccines2011-2012
Proj. AH2: Rapid Detection of Foreign, Emerging and Zoonotic Pathogens of Equines2011-2012
Proj. AH3: Risk Assessment Models for Emerging Infectious Diseases2011-2012
S1: CEEZAD Vaccine and Diagnostics Transboundary Animal Diseases Meeting2011-2012
S2: Lessons Learned Information Sharing (LLIS)/ Food, Agriculture and Veterinary Defense Project2011-2012