by _not_Exist_ | May 16, 2009 | 2009, HUMAN SHAPE INTERACTION, Karthik Ramani, Shape Understanding
Abstract: Background: The conventional superposition methods use an ordinary least squares (LS) fit for structural comparison of two different conformations of the same protein. The main problem of the LS fit that it is sensitive to outliers, i.e. large...
by _not_Exist_ | May 16, 2009 | 2009, HUMAN SHAPE INTERACTION, Karthik Ramani, Shape Understanding
Abstract: Background: Many molecules of interest are flexible and undergo significant shape deformation as part of their function, but most existing methods of molecular shape comparison (MSC) treat them as rigid bodies, which may lead to incorrect measure of...
by _not_Exist_ | Apr 16, 2009 | 2009, HUMAN SHAPE INTERACTION, Karthik Ramani, Shape Understanding
Abstract:A robust technique for determining the principal axes of a 3D shape represented by a point set, possibly with noise, is presented. We use techniques from robust statistics to guide the classical principal component analysis (PCA) computation. Our algorithm is...