|     Mechanical Engineering      Biomedical Engineering


H. Pajouhi, A.Y. Jou, R. Jain, A. Shakouri, C.A. Savran and S. Mohammadi, “Flexible complementary metal oxide semiconductor microelectrode arrays with applications in single cell characterization,” Applied Physics Letters, vol. 107, 203103, 2015. PDF

W. Huang, C-L. Chang, B-D. Chan, S.I. Jalal, D.E. Matei, P.S. Low and C.A. Savran, “Concurrent detection of cellular and molecular cancer markers using an immunomagnetic flow system,” Analytical Chemistry, vol. 87, no. 20, pp. 10161-10656, 2015. (Front cover of issue 20) PDF

H-H Wang, L. Wang, T.J. Jerde, B-D. Chan, C.A. Savran, G.N. Burcham, S. Crist and T.L. Ratliff, “Characterization of autoimmune inflammation induced prostate stem cell expansion,” The Prostate, vol. 75, no. 14, pp. 1620-1631, 2015. PDF

C-L. Chang, W. Huang, S.I. Jalal, B-D. Chan, A. Mahmood, S. Shahda, B.H. O'Neil, D.E. Matei and C.A. Savran, “Circulating tumor cell detection using a parallel flow micro-aperture chip system,” Lab On a Chip, vol. 15, no. 7, pp. 1677-1688, 2015. (Back cover of issue 7) PDF

B-D. Chan, K. Icoz, W. Huang, C-L. Chang, and C.A. Savran, “On-demand Weighing of Single Dry Biological Particles over a 5-order-of-magnitude Dynamic Range,” Lab On a Chip, vol. 14, no. 21, pp. 4188-4196, 2014. (Front cover of issue 21, Lab On a Chip 2014 "HOT Article") PDF

C-L. Chang, S.I. Jalal, W. Huang, A. Mahmood, D.E. Matei and C.A. Savran, “High-Throughput Immunomagnetic Cell Detection Using a Microaperture Chip System,” IEEE Sensors Journal , vol. 14, no. 9, pp. 3008-3013, 2014. PDF

R.L. Gieseck, B-D. Chan, and C.A. Savran, “A humidity-sensitive hydrogel-Bacillus spore composite for micropatterning of bimolecular gradients,” Review of Scientific Instruments, 84,085003 2013. PDF

B-D. Chan, K. Icoz, R.L. Gieseck, and C.A. Savran, “Selective weighing of individual microparticles using a hybrid micromanipulator-nanomechanical resonator system,” IEEE Sensors Journal, vol. 13, no. 8, pp. 2857-2862, 2013. PDF

C-L. Chang, Z. Ding, V. Patchigolla, B. Ziaie and C.A. Savran, “Reflective Diffraction Gratings from Hydrogels as Biochemical Sensors,” IEEE Sensors Journal, vol. 12, no. 7, pp. 2374-2379, 2012. PDF

B-D. Chan, F. Mateen, C-L. Chang, K. Icoz, and C.A. Savran, “A Compact Manually Actuated Micromanipulator,” Journal of Microelectromechanical Systems, vol. 21, no. 1, pp. 7-9, 2012. PDF

G. Chitnis, Z. Ding, C-L. Chang, C.A. Savran and B. Ziaie, “Laser-treated hydrophobic paper: an inexpensive microfluidic platform”, Lab On a Chip, DOI: 10.1039/C0LC00512F, 2011 PDF

K. Icoz, and C.A. Savran, “Nanomechanical Biosensing with Immunomagnetic Separation”, Applied Physics Letters, vol. 97, 123701, 2010. PDF

J. Lee, K. Icoz, A. Roberts, A.D. Ellington and C.A. Savran, “Diffractometric Detection of Proteins Using Microbead-Based Rolling Circle Amplification”, Analytical Chemistry, vol. 82, no 1, pp. 197-202, 2010. PDF

T.J. Lee, H. Zhang, C-L. Chang, C.A. Savran, and P. Guo “Engineering of the Fluorescent-Energy-Conversion Arm of Phi29 DNA Packaging Motor for Single-Molecule Studies”, Small, vol. 5, no 21, pp. 2453-2459, 2009. PDF

C-L. Chang, H. Zhang, D. Shu, P. Guo, and C. A. Savran, "Bright-field analysis of phi29 DNA packaging motor using a magnetomechanical system", Applied Physics Letters, vol. 93, 153902, 2008. PDF | Supporting information

K. Icoz, B. D. Iverson, and C.A. Savran, “Noise analysis and sensitivity enhancement in immunomagnetic nanomechanical biosensors”, Applied Physics Letters, vol. 93, pp. 013902, 2008. PDF

J. Lee, J. Jang, D. Akin, C.A. Savran, R. Bashir, “Real-time detection of airborne viruses on a mass-sensitive device”, Applied Physics Letters, vol. 93, pp. 013901, 2008. PDF

G. Acharya, C-L. Chang, D. Holland, D.H. Thompson, C.A. Savran, “Rapid Detection of S-Adenosyl Homocysteine Using Self-Assembled Optical Diffraction Gratings”, Angewandte Chemie International Edition, vol 47, no 6, pp 1051-1053, 2008. PDF

G. Acharya, C-L. Chang, D.D. Doorneweerd, E. Vlashi, W.A. Henne, L.C. Hartmann, P.S. Low, C.A. Savran, “Immunomagnetic Diffractometry for diagnostic serum markers”, Journal of the American Chemical Society vol 129, pp 15824-9, 2007. PDF

C-L. Chang, G. Acharya and C.A. Savran, “In situ fabricated diffraction grating for biomolecular detection”, Applied Physics Letters, vol. 90, pp. 233901-3, 2007. PDF

G. Acharya, D.D. Doorneweerd, C-L. Chang, W.A. Henne, P.S Low and C.A. Savran, “Label-Free Optical Detection of Anthrax-Causing Spores”, Journal of American Chemical Society, vol. 129, no. 4, pp. 732 -733, 2007. PDF

S. M. Knudsen, J. Lee, A.D. Ellington and C.A. Savran, “Ribozyme-Mediated Signal Augmentation on a Mass-Sensitive Biosensor”, Journal of American Chemical Society, vol. 128, no. 50, pp. 15936-15937, 2006. PDF

W.A. Henne, D.D. Doorneweerd, J. Lee, P.S. Low and C.A. Savran, “Detection of Folate Binding Protein with Enhanced Sensitivity Using a Functionalized Quartz Crystal Microbalance Sensor”,  Analytical Chemistry, vol. 78, no. 14, pp. 4880-4884, Jul. 2006 PDF

G. Acharya, C-L. Chang, C.A. Savran, "An optical biosensor for rapid and label-free detection of cells," Journal of American Chemical Society, vol. 128, pp 3862-3863, March 2006 PDF

C.A. Savran, S.M. Knudsen, A.D. Ellington and S.R. Manalis, “Micromechanical detection of proteins using aptamer-based receptor molecules”, Analytical Chemistry, vol. 76, no. 11, pp. 3194-3198, Jul. 2004 PDF

C.A. Savran, T.P. Burg, J. Fritz, and S.R. Manalis, “Microfabricated mechanical biosensor with inherently differential readout, Applied Physics Letters, vol. 83, no. 8, pp. 1659-1661, Aug. 2003 PDF

C.A. Savran, A.W. Sparks, J. Sihler, J. Li, W-C. Wu, D.E. Berlin, T.P. Burg, J. Fritz, M.A. Schmidt, S.R. Manalis, “Fabrication and Characterization of a micromechanical sensor for differential detection of nanoscale motions,” Journal of Microelectromechanical Systems, vol. 11, no. 6, pp. 703-708, Dec. 2002 PDF