Engineering Faculty Document No. 31-04
March 21, 2005
Page 1 of 4
TO: The Engineering Faculty
FROM: The Faculty of the Department of Biomedical Engineering
RE: New Dual Level Course
The faculty of the Department of Biomedical Engineering has approved the following new course. This action is now submitted to the Engineering Faculty with a recommendation for approval.
BME 553 Biomedical Optics
Sem. 1, Class 3,
cr. 3.
Prerequisite: PHYS 241 or equivalent, BIOL 295E or
equivalent
Course description: Optical methods applied to address biological and biomedical problems. Course includes two parts: fundamentals of optical microscopy and advanced techniques that are currently used to probe and/or manipulate cell and tissue samples.
Reasons: This course introduces biophotonics, a frontier area of biomedical engineering. A variety of advanced optical methods and their applications to biomedical research are presented. By taking this course, students will learn physical principles and practical methods of optical imaging. Students will also be able to incorporate what they learn in class to their research. This course has been taught twice on an experimental basis with an enrollment of 15 and 16 students.
George Wodicka
Professor and Head
Engineering Faculty Document No. 31-04
March 21, 2005
Page 2 of 4
1. Level: Graduate and Undergraduate
2. Course
Instructor: Ji-Xin Cheng
3. Course Outline:
Syllabus
Class 1 Basics of light
Class 2 Light matter interactions
Class 3 Principle of lasers and current laser technology
Class 4 Interactions of cells and tissues with light
Class 5 Principles of optical microscopy
Class 6 Diagnostic detection with optical spectroscopy and imaging
Class 7 Labor Day
Class 8 Confocal microscopy
Class 9 Exam 1
Class 10 Total internal reflection fluorescence microscopy
Class 11 Fluorescence energy transfer and lifetime imaging
Class 12 Literature review
Class 13 Two-photon fluorescence microscopy
Class 14 Nonlinear optics and second harmonic generation imaging
Class 15 Literature review
Class 16 Single molecule fluorescence detection and spectroscopy
Class 17 High-resolution imaging by near field optical microscopy
Class 18 Literature review
Class 19 Exam 2
Class 20 FTIR spectroscopy and imaging
Class 21 Spontaneous Raman microscopy and applications to diagnostic detection
Class 22 Literature review
Class 23 Coherent anti-Stokes Raman scattering microscopy
Class 24 Third harmonic generation microscopy
Engineering Faculty Document No. 31-04
March 21, 2005
Page 3 of 4
Class 25 Literature review
Class 26 Light fluctuation correlation spectroscopy
Class 27 Fluorescence recovery after photo bleaching and single particle tracking
Class 27 Literature review
Class 28 Methods for deep tissue imaging
Class 29 Literature review
Class 30 Optical and magnetic tweezers
Class 31 Literature review
Class 32 Light fluctuation correlation spectroscopy
Class 33 Literature review
Class 34 Biomedical imaging with nano materials
Class 35 Teraherz spectroscopy and imaging
Class 36 Optical biosensors
Class 37 Photodynamic therapy
Class 38 Exam 3
Class 39 Course review
Class 40 Student presentation of original proposals (final project)
Class 41 Student presentation of original proposals (final project)
Class 42 Student presentation of original proposals (final project)
Class 43 Student presentation of original proposals (final project)
Class 44 Student presentation of original proposals (final project)
Class 45 Final exam
Note for literature review: For each specific topic, two or three students will present in class a few recently published papers. Each student will submit a short paper that summarizes their comments on the significance, methods and results, strength and weakness of the papers.
Textbook: Introduction to Biophotonics (John Wiley & Sons, Inc. 2003)
Grading: Three exams 45%
Literature review 15%
Homework 20%
Final project 20%
Engineering Faculty Document No.31-04
March 21, 2005
Page 4 of 4
Documentation on
previous teaching
Fall semester of 2003
The total number of the registered students is 15, 4 of which from BME, 8 from Chemistry, 2 from ECE, 1 from ME. The result of the student evaluation is as follows
|
BME595Z
/ CHM 599Z |
From BME
|
From Chemistry |
|
Ave.
rate for the course |
4.6 |
4.8 |
|
Ave.
rate for the instructor |
4.2 |
4.8 |
Fall semester of 2004
The total number of the registered students is 16, 6 of which from BME, 8 from Chemistry, 2 from ME. The result of the student evaluation is as follows
|
BME595Z
/ CHM 599Z |
From BME
|
From
Chemistry |
|
Ave.
rate for the course |
3.7 |
3.8 |
|
Ave.
rate for the instructor |
3.3 |
3.6 |