[BNC-all] Cancer Nanotech seminar Dec 14 MRGN 121 11:30

Deborah Starewich dstarewi at exchange.purdue.edu
Wed Nov 29 11:47:08 EST 2006


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Oncological Sciences Center.
 
 
 
ONCOLOGICAL SCIENCES CENTER
Cancer Prevention Seminar Series
Building a community interested in cancer prevention and control research.


Plasmon-resonant Nanorods as Multifunctional Imaging Agents
 
Presented by
Alexander Wei
Associate Professor of Chemistry
 
December 14, 2006 
11:30 am
MRGN 121

Gold nanorods have several outstanding characteristics as optical contrast
agents for biomedical imaging. Their strong optical absorption at
near-infrared (NIR) frequencies can be used to generate contrast for optical
coherence tomography (OCT) imaging, and is well matched for detection
modalities based on differential albedo. Nanorods can also be imaged
directly by two-photon luminescence (TPL) with single-particle sensitivity,
and are sufficiently bright to support in vivo imaging applications. TPL
imaging has been used to study the uptake of ligand-functionalized nanorods
by tumor cells. Lastly, nanorods are excellent converters of light energy
into heat, with direct application in photothermal therapy.


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