{"id":365,"date":"2017-10-31T19:30:22","date_gmt":"2017-10-31T19:30:22","guid":{"rendered":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/?p=365"},"modified":"2017-11-08T00:23:37","modified_gmt":"2017-11-08T00:23:37","slug":"application-of-a-high-throughput-bioluminescence-based-method-and-mathematical-model-for-the-quantitative-comparison-of-polymer-microbicide-efficiency","status":"publish","type":"post","link":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/2017\/10\/31\/application-of-a-high-throughput-bioluminescence-based-method-and-mathematical-model-for-the-quantitative-comparison-of-polymer-microbicide-efficiency\/","title":{"rendered":"TR Stratton, RE Garc\u00eda, BM Applegate, JP Youngblood &#8220;Application of a High Throughput Bioluminescence-Based Method and Mathematical Model for the Quantitative Comparison of Polymer Microbicide Efficiency.&#8221;\u00a0\u00a0Biomacromolecules. 10(5):1173-1180, 2009."},"content":{"rendered":"<p>TR Stratton, RE Garc\u00eda, BM Applegate, JP Youngblood &#8220;<a class=\"gsc_vcd_title_link\" href=\"http:\/\/pubs.acs.org\/doi\/abs\/10.1021\/bm801416u\" target=\"_blank\" rel=\"noopener\" data-clk=\"hl=en&amp;sa=T&amp;ei=7eD4WZf7Jsq5mAHPuaXICQ\">Application of a High Throughput Bioluminescence-Based Method and Mathematical Model for the Quantitative Comparison of Polymer Microbicide Efficiency<\/a>.&#8221;\u00a0\u00a0<strong>Biomacromolecules<\/strong>. 10(5):1173-1180, 2009.<\/p>\n<h3>Abstract<\/h3>\n<div class=\"hlFld-Abstract\">\n<div id=\"abstractBox\">\n<p class=\"articleBody_abstractText\">Quaternized poly(4-vinyl pyridine)-based copolymers are known to be effective against a wide range of bacteria and possess biocompatible properties. Extensive testing of a wide range of copolymers is necessary to further explore and enhance the biocidal properties. However, testing is hampered by labor-intensive bacteria testing techniques. The present paper presents a new testing method, based on bioluminescent reporter strains to enable fast evaluation of bactericidal properties. The reported method enables us to create real-time characterization of bacteria behavior with far less labor than required through traditional testing methods. A mathematical model was also developed to characterize the change in bacteria populations exposed to biocides and to enable the quantitative comparison of minimum bactericidal concentrations.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p class=\"post-excerpt\" class=\"post-excerpt\">TR Stratton, RE Garc\u00eda, BM Applegate, JP Youngblood &#8220;Application of a High&hellip;<\/p>\n<div class=\"link-more\"><a href=\"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/2017\/10\/31\/application-of-a-high-throughput-bioluminescence-based-method-and-mathematical-model-for-the-quantitative-comparison-of-polymer-microbicide-efficiency\/\">Continue reading<span class=\"screen-reader-text\"> &#8220;TR Stratton, RE Garc\u00eda, BM Applegate, JP Youngblood &#8220;Application of a High Throughput Bioluminescence-Based Method and Mathematical Model for the Quantitative Comparison of Polymer Microbicide Efficiency.&#8221;\u00a0\u00a0Biomacromolecules. 10(5):1173-1180, 2009.&#8221;<\/span>&hellip;<\/a><\/div>\n<div class=\"link-more\"><a href=\"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/2017\/10\/31\/application-of-a-high-throughput-bioluminescence-based-method-and-mathematical-model-for-the-quantitative-comparison-of-polymer-microbicide-efficiency\/\">Continue reading<span class=\"screen-reader-text\"> \"TR Stratton, RE Garc\u00eda, BM Applegate, JP Youngblood &#8220;Application of a High Throughput Bioluminescence-Based Method and Mathematical Model for the Quantitative Comparison of Polymer Microbicide Efficiency.&#8221;\u00a0\u00a0Biomacromolecules. 10(5):1173-1180, 2009.\"<\/span>&hellip;<\/a><\/div>","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"advanced_seo_description":"","jetpack_publicize_message":"","jetpack_is_tweetstorm":false,"jetpack_publicize_feature_enabled":true},"categories":[45],"tags":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/peeeSR-5T","jetpack_likes_enabled":true,"jetpack-related-posts":[{"id":342,"url":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/2017\/10\/31\/challenges-and-results-for-quantitative-piezoelectric-hysteresis-measurements-by-piezo-force-microscopy\/","url_meta":{"origin":365,"position":0},"title":"BD Huey, R Nath, RE Garcia, JE Blendell &#8220;Challenges and results for quantitative piezoelectric hysteresis measurements by piezo force microscopy.&#8221; \u00a0Microscopy and Microanalysis. 11:6, 2005.","date":"10\/31\/2017","format":false,"excerpt":"BD Huey, R Nath, RE Garcia, JE Blendell \"Challenges and results for quantitative piezoelectric hysteresis measurements by piezo force microscopy.\" \u00a0Microscopy and Microanalysis. 11:6, 2005. Abstract Atomic Force Microscopy (AFM) has become a ubiquitous tool for analyzing the topography of a wide variety of materials, especially as nanoscale features become\u2026","rel":"","context":"In &quot;Papers&quot;","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":464,"url":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/2017\/11\/04\/bj-kim-re-garcia-ea-stach-kinetics-of-congruent-vaporization-of-zno-islands-physical-review-letters-10714146101-2011\/","url_meta":{"origin":365,"position":1},"title":"BJ Kim, RE Garc\u00eda, EA Stach &#8220;Kinetics of Congruent Vaporization of ZnO Islands.&#8221;\u00a0Physical Review Letters. 107(14):146101, 2011.","date":"11\/04\/2017","format":false,"excerpt":"BJ Kim, RE Garc\u00eda, EA Stach \"Kinetics of Congruent Vaporization of ZnO Islands.\"\u00a0Physical Review Letters. 107(14):146101, 2011. Abstract We examine the congruent vaporization of ZnO islands using in\u00a0situ transmission electron microscopy. Correlating quantitative measurements with a theoretical model offers a comprehensive understanding of the equilibrium conditions of the system, including\u2026","rel":"","context":"In &quot;Papers&quot;","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":468,"url":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/2017\/11\/04\/468\/","url_meta":{"origin":365,"position":2},"title":"B Vijayaraghavan, DR Ely, Y-M Chiang, R Garc\u00eda-Garc\u00eda, RE Garc\u00eda &#8220;An Analytical Method to Determine Tortuosity in Rechargeable Battery Electrodes.&#8221;\u00a0Journal of The Electrochemical Society. 159(5):A548-A552, 2012.","date":"11\/04\/2017","format":false,"excerpt":"B Vijayaraghavan, DR Ely, Y-M Chiang, R Garc\u00eda-Garc\u00eda, RE Garc\u00eda \"An Analytical Method to Determine Tortuosity in Rechargeable Battery Electrodes.\"\u00a0Journal of The Electrochemical Society. 159(5):A548-A552, 2012. Abstract In high energy density, low porosity, lithium-ion battery electrodes, the underlying microstructural tortuosity controls the macroscopic charge capacity, average lithium-ion diffusivity, and macroscopic\u2026","rel":"","context":"In &quot;Papers&quot;","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":359,"url":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/2017\/10\/31\/modelling-microstructures-with-oof2\/","url_meta":{"origin":365,"position":3},"title":"ACE Reid, RC Lua, RE Garc\u00eda, VR Coffman &#8220;Modelling microstructures with oof2.&#8221;\u00a0International Journal of Materials and Product Technology. 35(3):361-373, 2009.","date":"10\/31\/2017","format":false,"excerpt":"ACE Reid, RC Lua, RE Garc\u00eda, VR Coffman \"Modelling microstructures with oof2.\"\u00a0International Journal of Materials and Product Technology. 35(3):361-373, 2009. Abstract OOF2 is a program designed to compute the properties and local behaviour of material microstructures, starting from a two-dimensional representation, an image, of arbitrary geometrical complexity. OOF2 uses the\u2026","rel":"","context":"In &quot;Papers&quot;","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":477,"url":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/2017\/11\/04\/y-wang-dr-ely-re-garcia-progress-towards-modeling-microstructure-evolution-in-polycrystalline-films-for-solar-cell-applications-ieee-39th-photovoltaic-specialists-conference-pvsc-2\/","url_meta":{"origin":365,"position":4},"title":"Y Wang, DR Ely, RE Garc\u00eda &#8220;Progress towards modeling microstructure evolution in polycrystalline films for solar cell applications.&#8221;\u00a0IEEE 39th\u00a0Photovoltaic Specialists Conference (PVSC). 2056-2059, 2013.","date":"11\/04\/2017","format":false,"excerpt":"Y Wang, DR Ely, RE Garc\u00eda \"Progress towards modeling microstructure evolution in polycrystalline films for solar cell applications.\"\u00a0IEEE 39th\u00a0Photovoltaic Specialists Conference (PVSC). 2056-2059, 2013. Abstract Grain morphology has been long considered to be a major factor in the performance and efficiency of photovoltaic devices. Experimental work has demonstrated the effect\u2026","rel":"","context":"In &quot;Papers&quot;","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]},{"id":340,"url":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/2017\/10\/31\/finite-element-implementation-of-a-thermodynamic-description-of-piezoelectric-microstructures\/","url_meta":{"origin":365,"position":5},"title":"RE Garc\u00eda, SA Langer, WC Carter &#8220;Finite element implementation of a thermodynamic description of piezoelectric microstructures&#8221;\u00a0Journal of the American Ceramic Society. 88(3):742-749, 2005.","date":"10\/31\/2017","format":false,"excerpt":"RE Garc\u00eda, SA Langer, WC Carter \"Finite element implementation of a thermodynamic description of piezoelectric microstructures\"\u00a0Journal of the American Ceramic Society. 88(3):742-749, 2005. Abstract A model and numerical framework is developed for piezoelectric materials. The model treats the piezoelectric and electrostrictive effects by incorporating orientation-dependent, single-crystal properties. The method is\u2026","rel":"","context":"In &quot;Papers&quot;","img":{"alt_text":"","src":"","width":0,"height":0},"classes":[]}],"_links":{"self":[{"href":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/wp-json\/wp\/v2\/posts\/365"}],"collection":[{"href":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/wp-json\/wp\/v2\/comments?post=365"}],"version-history":[{"count":2,"href":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/wp-json\/wp\/v2\/posts\/365\/revisions"}],"predecessor-version":[{"id":563,"href":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/wp-json\/wp\/v2\/posts\/365\/revisions\/563"}],"wp:attachment":[{"href":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/wp-json\/wp\/v2\/media?parent=365"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/wp-json\/wp\/v2\/categories?post=365"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/engineering.purdue.edu\/ComputationalMaterials\/index.php\/wp-json\/wp\/v2\/tags?post=365"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}