... to lead in the research, development, and translation of implantable medical devices

 

Journal Publications


  1. 1.S. Raghunathan, A. Jaitli, P.P. Irazoqui, “Multi-Stage Seizure Detection Techniques Optimized for Low-Power Hardware Platforms,” Epilepsy & Behavior,  Vol. 22, 2011, pp. 561-568.                                                                 2011RaghunathanE&BHumanPublished.pdf


  1. 2.A. W. Conovaloff, B. L. Beier, P. P. Irazoqui, A. Panitch, “Effects of a synthetic bioactive peptide on neurite growth and nerve growth factor release in chondroitin sulfate hydrogels,” Biomatter,  Vol. 1, No. 2, 2011.


  1. 3.D. Ha, W.N. de Vries, S.W. John, P.P. Irazoqui, W.J. Chappell, “Polymer-Based Miniature Flexible Capacitive Pressure Sensor for Intraocular Pressure (IOP) Monitoring Inside a Mouse Eye,” Biomedical Microdevices, Published online, Oct. 2011.    2011HaIOPSensorPublished.pdf


  1. 4.E.Y. Chow, C.L. Yang, A. Chlebowski, S. Moon, P.P. Irazoqui, W.J. Chappell, “RF Powering for Miniature Implantable Biomedical Devices,” Institute of Electronics and Electrical Engineers Transactions on Antennas & Propagations, Vol. 59, No. 6, Jun. 2011, pp. 2379-2387.                                                                                                                             2011ChowTA&PRFPoweringPublished.pdf


  1. 5.S. Raghunathan, S. Gupta, H. Markandeya, P.P. Irazoqui, Kaushik Roy, “Ultra Low-Power Algorithm Design for Implantable Devices: Application to Epilepsy Prostheses,” Journal of Low Power Electronics and Applications,  Vol. 1, May 2011, pp. 175-203. 2011RagunathanJLPEAUltraLowPowerPublished.pdf


  1. 6.P. Rajdev, M.P. Ward, and P.P. Irazoqui, “Effect of Stimulus Parameters in the Treatment of Seizures by Electrical Stimulation in the Kainate Animal Model,” International Journal of Neural Systems, Vol. 21, No. 2, Apr. 2011, pp. 151–162. 2011RajdevIJNSStimParamPublished.pdf


  1. 7.M.S. Graves, T. Hassell, B.L. Beier, G.O. Albors, and P.P. Irazoqui, “Electrically Mediated Neuronal Guidance with Applied Alternating Current Electric Fields,” Annals of Biomedical Engineering, Vol. 39, No. 2, Feb. 2011, pp. 1759-1767. 2011GravesABMEFieldsPublished.pdf


  1. 8.E.Y. Chow, A. Chlebowski, P.P. Irazoqui, “A Miniature Implantable RF-Wireless Active Glaucoma Intraocular Pressure Monitor,” Institute of Electronics and Electrical Engineers Transactions on Biomedical Circuits and Systems, Vol. 4, No. 6, Dec. 2010, pp. 340-349.                                                                                                                     2010ChowTBioCASGlaucomaSystemPublished.pdf


  1. 9.B.L. Beier, K.M. Musick, A. Matsumoto, A. Panitch, E.A. Nauman, and P.P. Irazoqui, “Toward a Continuous Intravascular Glucose Monitoring System,” Sensors, Special Issue on Biodevices and Materials, Vol. 11, Dec. 2010, pp. 409-424. 2010BeierGlucosePublished.pdf


  1. 10.A.R. Kahn, E.Y. Chow, O. Abdel-Latief, P.P. Irazoqui, “Low-Power, High Data Rate Transceiver System for Implantable Prostheses,” International Journal of Telemedicine and Applications, Vol. 2010, Nov. 2010, doi:10.1155/2010/563903.    2010KahnTelemedecinePublished.pdf


  1. 11.K.M. Musick, A.C. Coffey, and P.P. Irazoqui, “Sensor to Detect Endothelialization on an Active Coronary Stent,” BioMedical Engineering OnLine, Vol. 9, No. 67, Nov. 2010.                                                                                 2010MusickRestenosisBMEOL.pdf


  1. 12.S. Raghunathan, S.K. Gupta, H. Markandeya, K. Roy and P.P. Irazoqui, “A Critical Comparison of Seizure Detection Features for an Implantable Epilepsy Prosthesis,” Journal of Neuroscience Methods, Vol. 193, 2010, pp. 106-117. 2010RaghunathanJNMDetectionPublished.pdf


  1. 13.E.Y. Chow, A. Chlebowski, S. Chakraborty, W.J. Chappell, and P.P. Irazoqui, “Fully Wireless Implantable Cardiovascular Pressure Monitor Integrated with a Medical Stent,” Institute of Electronics and Electrical Engineers Transactions on Biomedical Engineering, Vol. 57, No. 6, Jun. 2010, pp. 1487-1496.                                                                                     2010ChowTBMECardiacPublished.pdf


  1. 14.M.P. Ward and P.P. Irazoqui, “Evolving Refractory Major Depressive Disorder Diagnostic and Treatment Paradigms: Toward Closed-Loop Therapeutics,” Frontiers in Neuroengineering, Vol. 3, May 2010, doi: 10.3389/fneng.2010.00007.                                                                                                                                                                   2010WardDepressionPublished.pdf


  1. 15.P. Rajdev, M.P. Ward, R.M. Worth, J.L. Rickus, and P.P. Irazoqui, “Real-Time Seizure Prediction from Local Field Potentials using an Adaptive Wiener Algorithm,” Computers in Biology and Medicine, Vol. 40, No. 1, Jan. 2010, pp. 97-108.         2010RajdevPredictionPublished.pdf


  1. 16.E.Y. Chow, Y. Ouyang, B. Beier, P.P. Irazoqui, W.J. Chappell, “Evaluation of Cardiovascular Stents as Antennas for Implantable Wireless Applications,” Institute of Electronics and Electrical Engineers Transactions on Microwave Theory and Techniques, Vol. 57, No. 10, Oct. 2009, pp. 2523-2532.                                                                                                             2009ChowCardiacStentPublished.pdf


  1. 17.D.B. Jaroch, M.P. Ward, E.Y. Chow, J.L. Rickus, P.P. Irazoqui, “Magnetic Insertion System for Flexible Electrode Implantation,” Journal of Neuroscience Methods, Vol. 183, No. 2, Oct. 2009, pp. 213-222.                                                20009JarochMagElectrodePublished.pdf


  1. 18.E.Y. Chow, B. Beier, W.J. Chappell, P.P. Irazoqui, “Towards an Implantable Wireless Cardiac Monitoring Platform Integrated With an FDA Approved Cardiovascular Stent,” Journal of Interventional Cardiology, Vol. 22, No. 5, Oct. 2009, pp. 479-487.  2009ChowCardiacSystemPublished.pdf


  1. 19.S.C. Schachter, J. Guttag, S. Schiff, D.L. Schomer, P.P. Irazoqui, et al., “Advances in the Application of Technology to Epilepsy: The CIMIT/NIO Epilepsy Innovation Summit,” Epilepsy & Behavior, Vol. 16, No. 1, Sep. 2009, pp. 3-46.  20009SchachterEpilepsyReviewPublished.pdf


  1. 20.S. Raghunathan, S.K. Gupta, M.P. Ward, R.M. Worth, K. Roy, P.P. Irazoqui, “The Design and Hardware Implementation of a Low-Power Real-Time Seizure Detection Algorithm,” Journal of Neural Engineering, Vol. 6, Aug. 2009, p. 056005.     20009RaghunathanDetectionPublished.pdf


  1. 21.M.P. Ward, P. Rajdev, C. Ellison, P.P. Irazoqui, “Toward a Comparison of Microelectrodes for Acute and Chronic Recordings,” Brain Research, Vol. 1282, Jul. 2009, pp. 183-200.                                                                                         20009WardElectrodeComparoPublished.pdf


  1. 22.S.S. Jedlicka, M. Dadarlat, T. Hassell, Y. Lin, A. Young, M. Zhang, P.P. Irazoqui, J.L. Rickus, “Calibration of Neurotransmitter Release from Neural Cells for Therapeutic Implants,” International Journal of Neural Systems, Vol. 19, No. 3, Jun. 2009, pp. 197-212.                                                                                                                                     2009JedlickaHybridElectrodePublished.pdf


  1. 23.E.Y. Chow, C.L. Yang, A. Chlebowski, S. Moon, W.J. Chappell, P.P. Irazoqui, “Implantable Wireless Telemetry Boards for in-vivo Transocular Transmission,” Institute of Electrical and Electronics Engineers Transactions on Microwave Theory & Techniques, Vol. 56, No. 12, Dec. 2008, pp. 3200-3208.                                                                                                         2009ChowIOPPublished.pdf


  1. 24.M. Rokkam, M.R. Chatni, A. ul Haque, A.R. DeCarlo, B.F. Robinson, P.P. Irazoqui, D.M. Porterfield, “High-Density Data Acquisition System and Signal Preprocessor for Interfacing with Microelectromechanical System-Based Biosensor Arrays,” Review of Scientific Instruments, No. 78, Apr. 2007, pp. 44303-44312.                                                                                                                                                        2007DAQRokkamPublished.pdf


  1. 25.A. ul Haque, M. Rokkam, A.R. DeCarlo, S.T. Wereley, H.W. Wells, W.T. McLamb, S.J. Roux, P.P. Irazoqui, D.M. Porterfield, “A MEMS Fabricated Cell Electrophysiology Laboratory Biochip for In-silico Calcium Measurements,” Sensors and Actuators, Vol. 123, 2007, pp. 391-399.                                                                                                                                                                    2007MISAulHaquePublished.pdf


  1. 26.A. ul Haque, A.R. DeCarlo, M. Rokkam, S.T. Wereley, P.P. Irazoqui, H.W. Wells, W.T. McLamb, S.J. Roux, D.M. Porterfield, “Design, Fabrication and Characterization of an In Silico Cell Physiology Lab for Bio Sensing Applications,” Journal of Physics Conference Series, Vol. 34, 2006, pp. 740-746.                                                                                                                                                                      2006OptrodeulHaquePublished.pdf


  1. 27.P.P. Irazoqui, I. Mody, J.W. Judy, “Inductive Powering in Miniature Implantable Neural Recording Devices,” IEEE EMBS Magazine, Dec. 2005, pp. 48-54.                                                                                                                                                 2005IrazoquiEMBSPublished.pdf


Conference Proceedings


  1. 1.B.L. Beier, E.M. Brandner, K.M. Musick, A. Matsumoto, A. Panitch, E.A. Nauman, and P.P. Irazoqui, “Preliminary Characterization of a Glucose-Sensitive Hydrogel,” Proceedings of the IEEE Engineering in Medicine and Biology Conference, Buenos Aires, Argentina, Sep 2010.                                                                                                                                                      2010BeierEMBSHydrogel.pdf


  1. 2.E.Y. Chow, D.Ha, T. Lin, W.N. deVries, S.W.M. John, W.J. Chappell, and P.P. Irazoqui, “Sub-Cubic Millimeter Intraocular Pressure Monitoring Implant to Enable Genetic Studies on Pressure-Induced Neurodegeneration,” Proceedings of the IEEE Engineering in Medicine and Biology Conference, Buenos Aires, Argentina, Sep 2010.                                                 2010ChowEMBSHHMIIOP.pdf


  1. 3.H. Markandeya, G. Karakonstantis, S. Raghunathan, P.P. Irazoqui, and K. Roy ”Low-Power DWT-Based Quasi-Averaging Algorithm and Architecture for Epileptic Seizure Detection," International Symposium on Low-Power Electronics and Design (ISLPED), Aug 2010, pp. 301-306.                                                                                                                          2010MarkandeyaISLPEDPublished.pdf


  1. 4.D. Ha, B.G. Kim, T. Lin, Y. Ouyang, P.P. Irazoqui, and W.J. Chappell “3D Packaging Technique on Liquid Crystal Polymer (LCP) for Miniature Wireless Biomedical Sensor,” Proceedings of the Microwave Theory and Techniques Symposium, Anaheim, CA, May, 2010.                                                                                                                                                            2010DohyukMTTPublished.pdf


  1. 5.M.M. Grafton, M.D. Zordan, H.S. Chuang, P. Rajdev, P.P. Irazoqui, S.T. Wereley, A.L.. Jones, R. Byrnes, P.W. Todd, J.F. Leary ”Portable Microfluidic Cytometer for Whole Blood Cell Analysis," Proceedings of the SPIE, Vol. 7593, Feb 2010, pp. 75930M-75930M-8. 


  1. 6.E.Y. Chow, S. Chakraborty, W.J. Chappell, P.P. Irazoqui, “Mixed-Signal Integrated Circuits for Self-Contained Sub-Cubic Millimeter Biomedical Implants,” Proceedings of the International Solid State Circuits Conference (ISSCC), San Francisco, CA (Feb, 2010) 2010ChowISSCCPublished.pdf


  1. 2.E.Y. Chow, P.P. Irazoqui, "High-Frequency Transmitters for Implantable Applications," IEEE Circuits and Systems for Medical and Environmental Applications Workshop, Merida, Yucatan, Mexico (Dec 14-16, 2009)


  1. 3.P. Rajdev, B. Manola, P.P. Irazoqui; “A low power, high compliance neural stimulator” IEEE Circuits and Systems for Medical and Environmental Applications Workshop, Merida, Yucatan, Mexico (Dec 14-16, 2009)


  1. 4.E.Y. Chow, B.L. Beier, Y. Ouyang, W.J. Chappell, P.P. Irazoqui “High Frequency Transcutaneous Transmission Using Stents Configured as a  Dipole Radiator for Cardiovascular Implantable Devices,” Proceedings of the Microwave Theory and Techniques Conference, Boston, MA (Jun, 2009).                                                                                                                                                 2009ChowMTTPublished.pdf


  1. 5.S. Raghunathan, M.P. Ward, K. Roy, P.P. Irazoqui “A Low-power Implantable Event-based Seizure Detection Algorithm,” 3rd International IEEE EMBS Conference on Neural Engineering, Antalya, Turkey (Apr, 2009).


6.C.L. Yang, E.Y. Chow, P.P. Irazoqui, W. Chappell, “RF Powering for Embedded

Glaucoma Sensors in Miniature Packages,” Proceedings of the URSI General Assembly, Chicago, IL (Aug, 2008).


  1. 7.E.Y. Chow, C.L. Yang, W. Chappell, P.P. Irazoqui “Miniature Antenna for RF Telemetry through Ocular Tissue,” Proceedings of the Microwave Theory and Techniques Conference, Atlanta, GA (Jun, 2008).                                                                                         2008ChowMTTPublished.pdf


  1. 8.J.L. Rickus, P.P. Irazoqui, “Controlled GABA Release from a Hybrid Cell Silicon Neural Prosthetic,” American Epilepsy Society, Philadelphia, PA (Dec 2007).


  1. 9.E.Y. Chow, A. Kahn, P.P. Irazoqui, “High Data Rate 6.7 GHz Wireless ASIC Transmitter for Neural Prostheses,” Proceedings of the IEEE Engineering in Medicine and Biology Conference, Lyon, France (Aug 22-26, 2007).


  1. 10.R.P. Dresher, P.P. Irazoqui, “A Compact Nanopower Low Output Impedance CMOS Operational Amplifier for Wireless Intraocular Pressure Recordings,” Proceedings of the IEEE Engineering in Medicine and Biology Conference, Lyon, France (Aug 22-26, 2007).


  1. 11.T.J. Hassell, S.S. Jedlicka, J.L. Rickus, P.P. Irazoqui, “Constant-Current Adjustable Waveform Microstimulator for an Implantable Bi-Modal Output Hybrid Neural Prosthesis,” Proceedings of the IEEE Engineering in Medicine and Biology Conference, Lyon, France (Aug 22-26, 2007).


  1. 12.E.Y. Chow, J.L. Rickus, P.P. Irazoqui, “RF Telemetry ASICS Enabling Neural Prosthetics for Epilepsy,” American Epilepsy Society, San Diego, CA (Dec 2006).


  1. 13.P.P. Irazoqui, “Clinical Neural Prosthetic Devices for Epilepsy and Spinal-Cord Injury Repair,” National Academies Keck Futures Initiative, Irvine, CA (Nov 8-12, 2006).


  1. 14.A.R. De Carlo, M. Rokkam, A. ul Haque, S.T. Wereley, P.P. Irazoqui, H.W. Wells, W.T. McLamb, S.J. Roux, D.M. Porterfield, “Development of a Microfluidic Ion Sensor Array (MISA) to Monitor Gravity-Dependent Calcium Fluxes in Ceratopteris Spores,” Gravit. and Space Biol. Bull. 2006.


  1. 15.J.L. Rickus, P.P. Irazoqui, “Hybrid Cellular-Silicon Engineered Devices for Neural Prosthetics,” NIH Neural Interfaces Workshop, Bethesda, MD (Sep 2005).


  1. 16.J. Morizio, P.P. Irazoqui, V.L. Go, J. Parmentier, “Wireless Headstage for Neural Prosthetics,” 2nd International IEEE EMBS Conference on Neural Engineering, Washington, D.C. (Mar, 2005).


  1. 17.P.P. Irazoqui, I. Mody, J.W. Judy, “In-Vivo EEG Recording Using a Wireless Implantable Neural Transceiver,” 1st International IEEE EMBS Conference on Neural Engineering, Capri Island, Italy (Mar 20-22, 2003).


  1. 18.P.P. Irazoqui, I. Mody, J.W. Judy, “Transcutaneous RF-Powered Neural Recording Device,” 24th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Houston, TX (Oct 23-26, 2002), pp. 325.


  1. 19.D.L. Ringach, C.E. Bredfeldt, J.D. Dorn, D. Spriggs, P.P. Irazoqui (2000) “Dynamics of spatial frequency selectivity in macaque primary visual cortex,” Invest Ophthal & Vis Sci 41(4): 1749.


  1. 20.J.W. Judy, H. Yang, P.P. Irazoqui, K. Yang, N. Myung, M. Schwartz, K. Nobe, “Ferromagnetic Micromechanical Magnetometers,” Late News Tech. Dig. Solid-State Sensor and Actuator Workshop (Hilton Head 2000), Hilton Head Island, SC (Jun 4-8, 2000), pp. 15-16.


  1. 21.P.P. Irazoqui, J.T. Bernhard, “Examining the Performance Benefits of Antenna Diversity Systems in Portable Wireless Environments,” IEEE Allerton Conference, Sep 1999.


  1. 22.P.P. Irazoqui, J.T. Bernhard, C. Short, E. Swanson, “An Analysis and Design Tool for Evaluation of Integrated Antenna Diversity Systems in Portable Wireless Devices,” IEEE Symposium on Antennas and Propagation, Jun 1999.


  1. 23.J.C. Jalbert, P.P. Irazoqui, S. Miles, D.R. Blidberg, and D. James, "Solar AUV Technology Evaluation and Development Project,” International Symposium on Unmanned Untethered Submersible Technology, Sep 7-10, 1997, pp. 69-75.



Theses


  1. 1.B. Bercich, “Robotic Arm for Testing and Demonstration of Targeted Muscle Reinnervation with Implications for Low-Cost Upper-Limb Prostheses,” M.S. Thesis, Weldon School of BME, Purdue University, West Lafayette,  (Apr 2011).


  1. 2.S. Sadaria, “Wireless Single Channel Sensor for Targeted Muscle reinnervation,” M.S. Thesis, Weldon School of BME, Purdue University, West Lafayette,  (Apr 2011).


  1. 3.P. Rajdev, “Seizure Prediction and Optimized Control Algorithms for Epilepsy Prostheses,” Ph.D. Dissertation, Weldon School of BME, (Feb 2011).


  1. 4.T. Hassell, “A Wireless Implantable System For The Real-Time Surveillance And Modulation of Central Nervous System Recovery Following Spinal Cord Injury,” Ph.D. Dissertation, Weldon School of BME, (Dec 2010).


  1. 5.S. Raghunathan, “Low-power seizure detection hardware on integrated neural recording platforms for closed-loop epilepsy prostheses,” Ph.D. Dissertation, Weldon School of BME, (Nov 2010).


  1. 6.B.L. Beier, “Toward a Continuous Intravascular Glucose Monitoring System,” M.S. Thesis, Weldon School of BME, Purdue University, West Lafayette,  (Apr 2010).


  1. 7.A.R. Kahn, “A High Data-Rate Wireless Receiver for Implantable Biomedical Devices,” M.S. Thesis, Weldon School of BME, Purdue University, West Lafayette,  (Apr 2010).


  1. 8.G.O. Albors, “A Programmable Wireless Oscillating Field Stimulator,” M.S. Thesis, Weldon School of BME, Purdue University, West Lafayette, (Dec 2009).


  1. 9.A.L. Chlebowski, “Advanced Radio Frequency Materials for Packaging of Implantable Biomedical Devices,” M.S. Thesis, Weldon School of BME, Purdue University, West Lafayette, (Jul 2009).


  1. 10.M.S. Graves, “High Duty-Cycle AC Stimulation for Electrically-Mediated Spinal Cord Therapy,” M.S. Thesis, Weldon School of BME, Purdue University, West Lafayette, (Jul 2009).


  1. 11.E.Y. Chow, “Wireless Miniature Implantable Devices and ASICS for Monitoring Treatment and Studty of Glaucoma and Cardiac Disease,” Ph.D. Dissertation, School of ECE, Purdue University, West Lafayette, (May 2009).


  1. 12.E.Y. Chow, “High Data-Rate Wireless Transcutaneous-Telemetry using High-Frequency ASICs for Neural Prostheses,” M.S. Thesis, School of ECE, Purdue University, West Lafayette, (May 2007).


  1. 13.P.P. Irazoqui, “Transcutaneous Inductively-Powered Neural Recording System,” Ph.D. Thesis, BME Department, University of California, Los Angeles, (May 2003).


  1. 14.P.P. Irazoqui, “Evaluation of Integrated Antenna Diversity Systems,” M.S. Thesis, ECE Department, University of New Hampshire, Durham, (May 1999).

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