Graduate Program in Musculoskeletal and Orthopaedic Innovation (MOI)

Orthopaedics has long been an integral part of biomedical research and education and one of the driving forces in the medical devices industry. The graduate program in Musculoskeletal and Orthopaedic Innovation (MOI) will produce academically well-trained graduate level biomedical engineers in the fields of orthopaedics and musculoskeletal research. Students trained through the program will be equipped with the fundamental and holistic understanding specific to orthopaedics which will render them more competitive and efficient as leaders in the industry, research institutions, academia, health care institutions and other related professional organizations.

This program will:

  • prepare outstanding graduate students with strong backgrounds in the fundamentals of engineering and significant cross-disciplinary expertise in the areas of musculoskeletal materials, mechanics, devices and disease processes
  • promote excellence and diversity in biomedical engineering education through enhancing the interaction of Purdue and Indiana University School of Medicine faculty in the diverse fields of engineering, veterinary clinical sciences, basic medical sciences, and nutrition, around the integrated discipline of Orthopaedics
  • uphold and advance the field's standards, ethics, and integrity
  • enhance the career development of students in this emerging field through engagement with the industry, entrepreneurs and clinicians

Admissions Requirements:

Applicants should have at least a Bachelor of Science (BS) degree in engineering or in a field such as chemistry, biophysics or physics or in life science fields such as biology, veterinary sciences or biochemistry with significant quantitative components. Scores from the GRE, TOEFL (non-native English speakers), and at least three (3) letters of recommendation will be required. Evidence of a strong foundation of research or research potential will be required.

Research Opportunities:

The diversity of faculty members participating provides a wealth of research opportunities that span the field of orthopaedic implants, advanced biomaterials for replacement of hard and soft tissues, orthobiologics, stem cells within a musculoskeletal context, nanobiomechanics, imaging and biosensors. Research areas will include, but not be limited to:

  • The study of musculoskeletal tissues: tissue engineering of tendon, ligament and bone; understanding the interactions between extracellular matrices and cells, mechanobiological responses of cells/tissues, micro and nanoscale failure mechanics of skeletal tissues, assessment of in-service tissue loading via dynamic motion analysis, development of non-invasive sensing systems for assessment of tissue integrity
  • The study of orthopaedic implants: Biomechanics, design, biocompatibility, pre-clinical evaluation of implants, development of next generation smart/instrumented implants
  • The study of musculoskeletal biomaterials: The development of bioactive, biomimetic advanced biological materials for replacement of aged and diseased musculoskeletal tissues

Research opportunities will range from fundamental studies of biological structures to applied medical device design and evaluation. Many of the projects will be collaborative in nature, involving researchers from various Purdue Colleges and Schools as well as the Indiana University School of Medicine.

In addition, participants can learn about entrepreneurship through the Biomedship program. The Weldon School of Biomedical Engineering has teamed with the Krannert School of Management and the Indiana University School of Medicine to create this unique graduate experience that is designed to provide the next generation of leaders in biomedical innovation, commercialization, and management.

Students will receive stipends from funding sources including assistantships (both teaching and research) and fellowships (both internal and external) for the length of their tenure as long as they are making sufficient progress toward graduation.

The MOI Team


Weldon School of Engineering
206 S. Martin Jischke Drive
West Lafayette, IN 47907-2032

Associate Directors

Eric Nauman
Associate Professor of Biomedical Engineering
Associate Professor of Mechanical Engineering
Department of Mechanical Engineering
575 Stadium Mall Drive
West Lafayette, IN 47907-2091

Gert Breur
Professor of Veterinary Clinical Sciences
School of Veterinary Medicine
575 Stadium Mall Drive
West Lafayette, IN 47907-2091

Executive Committee

Eric Nauman
Gert Breur
Stacey Mobley
Hiroki Yokota
Riyi Shi
George Wodicka (ex-oficio)

Participating members

Eric Nauman Biomedical Engineering, Mechanical Engineering
David Burr IUPUI, Orthopaedic Surgery
Tien-Min Gabriel Chu IUPUI, Orthopaedic Surgery and Restorative Dentistry
Lynetta Freeman Veterinary Medicine
Kevin Hannon Basic Medical Sciences
Klod Kokini Mechanical Engineering
Tim Lescun Veterinary Medicine
Stacey Mobley Nutrition
Corey Neu Biomedical Engineering
Alyssa Panitch Biomedical Engineering
Bill Peine Mechanical Engineering
Amber Pond Basic Medical Sciences
Masa Rao Mechanical Engineering
Shirley Rietdyk Biomechanics
Mark Seifert IUPUI
Thomas Siegmund Mechanical Engineering
Riyi Shi Biomedical Engineering, Basic Medical Sciences
Sherry Voytik-Harbin Biomedical Engineering
Bruce Watkins Basic Medical Sciences
Connie Weaver Nutrition
Hiroki Yokota IUPUI, Anatomy and Cell Biology
Dong Xie IUPUI, Surgery