Dr. Jacqueline Linnes

Areas of Research

point-of-care diagnostics, wearable devices, nucleic acid amplification, antigen-antibody binding, molecular diagnostics, health disparities


The Linnes Lab at Purdue University is driven by the pressing need for real-time detection technologies to prevent, diagnose, and better understand the pathogenesis of diseases. We focus on non-invasive sample collection, microfluidic sample preparation, and automated detection of biomolecules and electrophysiologic signals to efficiently diagnose and monitor both infectious and non-communicable diseases. Applications of this work range from global health to biodefense to personalized medicine.

By cultivating curiosity, creativity, and resourceful engineering, we use fundamental science to develop inspired solutions to difficult diagnostic challenges with immediate health applications. These technologies are tested against rigorous engineering standards with real biological samples and in actual use settings. We with work open access networks, startups and large companies on a variety of grant, foundation, and industry-funded research to enable translation into the real world. Devices in the lab are co-developed with end-users to ensure that these technologies are robust and accessible to the clinicians, technicians, and patients who need them.

The Linnes Lab is part of the Global Engineering Program's Shah Family Global Innovation Lab, the Regenstrief Center for Healthcare Engineering, Purdue Autism Research Center (PARC), SMART Films Consortium, and the Purdue Institute of Inflammation, Immunology, and Infectious Disease (Pi4D). These programs facilitate collaborations across campus and around the world. Dr. Linnes strongly encourages local and international travel and exchanges to clinical partner sites and active participation at research conferences each year.

Recruitment Needs

Collaborative, resourceful PhD students to work on:

1) Developing paper-based molecular diagnostics for scalable reel-to-reel manufacturing.
2) Wearable vital signs monitoring of opioid-exposed infants and children with autism to support collaborators developing new behavioral interventions.

Please feel free to contact Dr. Linnes directly.

Email: jlinnes@purdue.edu

Lab Website: https://engineering.purdue.edu/LinnesLab/