BME Seminar - Wed., February 19th

Event Date: February 19, 2014
Hosted By: Weldon School of Biomedical Engineering
Time: 9:30 a.m.
Location: MJIS 1001, WL campus
Dr. Hyowon Lee, Senior Advanced Process Development Engineer in the Neuromodulation Division of St. Jude Medical will present a seminar on Wednesday, February 19th, at 9:30 a.m. in MJIS 1001.

His seminar, entitled "Development of Implantable Microdevices to Improve Hydrocephalus Treatment" will be part of his candidacy for a faculty position in the Weldon School, and will be presented as part of the BME seminar series.


Hydrocephalus is a debilitating neurological disorder for which there is no cure. The treatment of hydrocephalus typically requires chronic implantation of a shunt system to manage intracranial pressure. Unfortunately, these shunt systems suffer from a high failure rate (>40%) within the initial year of implantation due to progressive cellular occlusion at the inlet pores of the catheter. The estimated annual cost for treating hydrocephalus in the US exceed $1 billion.

To combat the cellular obstruction, I have designed, fabricated, and evaluated novel magnetic microactuators to be integrated into ventricular catheters. Device evaluation included static and dynamic mechanical responses; MRI compatibility issues due to ferromagnetic elements; and static and dynamic in vitro functional evaluation. The results to date indicate good control of fabricated devices, minimum MRI concerns, and strong cell-clearing capabilities of microdevices to maintain pore patency.

~Faculty Candidate~

~BME Faculty Host: Pedro Irazoqui~

***Coffee and juice will be provided at West Lafayette***